| Entry |
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| Name |
farnesyl diphosphatase;
FPP phosphatase
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| Class |
Hydrolases;
Acting on ester bonds;
Diphosphoric-monoester hydrolases
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| Sysname |
(2E,6E)-farnesyl-diphosphate diphosphohydrolase
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| Reaction(IUBMB) |
(2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-farnesol + diphosphate [RN: R08697]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme is involved in the biosynthesis of acyclic sesquiterpenoids [1].
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| History |
EC 3.1.7.6 created 2010
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| Pathway |
| ec00900 | Terpenoid backbone biosynthesis |
| ec00909 | Sesquiterpenoid and triterpenoid biosynthesis |
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| Orthology |
| K15793 | acyclic sesquiterpene synthase |
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| Genes |
| TDC: | 119356231 119356232 119365401 119365402 |
| TAES: | 100873133 123041882 123041883 123054327 123190213 123191849 |
| PVIR: | 120640652 120683675 |
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| Reference |
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| Authors |
Song L |
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| Title |
A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol. |
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| Journal |
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| Reference |
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| Authors |
Tsai SC, Gaylor JL. |
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| Title |
Testicular sterols. V. Preparation and partial purification of a microsomal prenol pyrophosphate pyrophosphohydrolase. |
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| Journal |
J Biol Chem 241:4043-50 (1966) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.1.7.6 |
| ExPASy - ENZYME nomenclature database: | 3.1.7.6 |
| BRENDA, the Enzyme Database: | 3.1.7.6 |
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