KEGG ENZYME: 3.2.1.70

ENZYME: 3.2.1.70

Entry

EC 3.2.1.70                 Enzyme

Name

glucan 1,6-alpha-glucosidase;
exo-1,6-beta-glucosidase;
glucodextrinase;
glucan alpha-1,6-D-glucohydrolase

Class

Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

Sysname

glucan 6-alpha-D-glucohydrolase

Reaction(IUBMB)

Hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides

Comment

Hydrolysis is accompanied by inversion at C-1, so that new reducing ends are released in the beta-configuration. Dextrans and isomaltosaccharides are hydrolysed, as is isomaltose, but very slowly. The enzyme from some sources also possesses the activity of EC 3.2.1.59 (glucan endo-1,3-alpha-glucosidase).

History

EC 3.2.1.70 created 1972, modified 2001

Orthology

K01215

glucan 1,6-alpha-glucosidase

Genes

VFI:	VF_A0731(treC)

AHA:

AHA_3172

AHY:	AHML_17010

AHD:	AI20_03515

AHR:	V428_17665

AHP:	V429_17700

AHJ:	V469_05595

AHH:	RY45_16360

AHI:	VU14_05795

AAJ:	BOQ57_16250

ASA:

ASA_1144

AEO:	O23A_p0318

AVR:

B565_0987

AVO:	AMS64_06675

ADH:	CK627_09905

AEM:	CK911_11965

ARV:	C7N77_19230

AALL:

I6G90_10545 I6G90_11145

AJD:	I6H43_16220

AEJ:	E5E97_21500

ABES:

IU367_05620

BACQ:

DOE78_12190

BCIR:

C2I06_02105

LGZ:	NCTC10812_00437(malL_2)

PPOL:

X809_29080

PPQ:	PPSQR21_025180

PSAB:

PSAB_07125 PSAB_11490

PDU:	PDUR_08170 PDUR_13125

PBD:	PBOR_08180

PGM:	PGRAT_08015

PAEN:

P40081_08210

PAEF:

R50345_07305

PAEQ:

R50912_07465

PSTE:

PSTEL_21505

PSON:

JI735_16605

PPEO:

ABE82_13130

PXL:	BS614_19650

PBAC:

HUB98_02215

PSOP:

KP014_10845 KP014_16340

PTRI:

KDC22_06915

PTJ:	JRJ22_06405

PMAH:

PTQ21_19860

PAMY:

P9222_21690

PPAB:

KET34_15830

LLA:	L124628(dexB) L128693(dexA)

LLK:	LLKF_1606(dexB) LLKF_1840(dexA)

LLT:	CVCAS_1398(dexB) CVCAS_1590(dexA)

LLS:	lilo_1410(dexB) lilo_1660(dexA)

LLD:	P620_08180 P620_09460

LLX:	NCDO2118_1507(dexB) NCDO2118_1781(dexA)

LLJ:	LG36_0884(dexB) LG36_1631(dexA)

LLM:	llmg_0741(dexA)

LLC:

LACR_1851

LLR:

llh_4030

LLN:	LLNZ_03860

LLI:	uc509_1633(dexA)

LLW:	kw2_1440 kw2_1648

LGR:

LCGT_1258

LGV:

LCGL_1279

LPK:	LACPI_1446(dexB)

LRN:	CMV25_09095

LACT:

D7I46_02490 D7I46_06265

LACK:

FLP15_11420

LTI:	JW886_07995

LCAR:

BHS00_03910

LPAA:

BHS01_04110

LPET:

lgb_01287(dexB)

LFO:	LMK00_07535

SPY:	SPy_1973(dexB)

SPZ:	M5005_Spy1681(dexB)

SPYM:

M1GAS476_0255(dexB)

SPYA:

A20_1728c(dexB)

SPM:	spyM18_2039

SPG:	SpyM3_1695(dexB)

SPS:

SPs1697

SPH:	MGAS10270_Spy1750(dexB)

SPI:	MGAS10750_Spy1775(dexB)

SPJ:	MGAS2096_Spy1704(dexB)

SPK:	MGAS9429_Spy1684(dexB)

SPF:	SpyM51652(dexB)

SPA:	M6_Spy1689

SPB:	M28_Spy1669(dexB)

STG:	MGAS15252_1526(dexB)

STX:	MGAS1882_1587(dexB)

SOZ:	Spy49_1627c(dexB)

STZ:	SPYALAB49_001667(dexB)

SPYH:

L897_08420

SPN:	SP_0342(dexB)

SPD:	SPD_0311(dexB)

SPR:	spr0310(dexB)

SPW:	SPCG_0345(dexB)

SJJ:

SPJ_0334

SNV:	SPNINV200_03080(dexB)

SPX:	SPG_0311(dexB)

SNT:

SPT_0391

SND:

MYY_0424

SPNN:

T308_01725

SNE:	SPN23F03150(dexB)

SPV:

SPH_0452

SNC:	HMPREF0837_10644

SNM:	SP70585_0406

SPP:

SPP_0377

SNI:	INV104_02940(dexB)

SPNG:

HMPREF1038_00390(dexB)

SNB:	SP670_0411

SNP:

SPAP_0372

SNX:	SPNOXC03500(dexB)

SNU:	SPNA45_01694(dexB)

SPNE:

SPN034156_14070(dexB)

SPNU:

SPN034183_03570(dexB)

SPNM:

SPN994038_03450(dexB)

SPNO:

SPN994039_03460(dexB)

SAG:	SAG1924(dexB)

SAN:

gbs1911

SAK:	SAK_1883(dexB)

SGC:	A964_1783(dexB)

SAGS:

SaSA20_1580(dexB)

SAGM:

BSA_19410

SAGI:

MSA_20100

SAGR:

SAIL_19430

SAGT:

GBSCOH1_1717

SAGE:

EN72_10095

SAGG:

EN73_09185

SAGN:

W903_1860(dexB)

SAGJ:

ID870_00320

SMU:	SMU_883(dexB)

SMC:	SmuNN2025_1131(dexB)

SMUT:

SMUGS5_03935

SMJ:	SMULJ23_1129(dexB)

SMUA:

SMUFR_0771(dexB)

STC:

str1886

SSB:	SSUBM407_1445(dexB)

SSU:	SSU05_1554

SSV:	SSU98_1562

SSI:	SSU1368(dexB)

SSS:	SSUSC84_1398(dexB)

SSF:	SSUA7_1385

SSW:	SSGZ1_1385

SUP:

YYK_06505

SSUS:

NJAUSS_1435

SST:	SSUST3_1395(dexB)

SSUY:

YB51_6870

SSK:	SSUD12_1508

SSQ:	SSUD9_1542

SUI:	SSUJS14_1520

SUO:	SSU12_1498

SRP:	SSUST1_1433

SSUT:

TL13_1360(dexB)

SSUI:

T15_1553(dexB)

SEZ:	Sez_1771(dexB)

SEQ:

SZO_01960

SEZO:

SeseC_02406(dexB)

SEQU:

Q426_10285

SEU:

SEQ_2011

SUB:	SUB0246(dexB)

SDS:

SDEG_0236

SDG:	SDE12394_01030

SDA:	GGS_0219(dexB)

SDC:	SDSE_0242(dexB)

SDQ:	SDSE167_0245

SGA:	GALLO_0196

SGG:	SGGBAA2069_c02140(dexB)

SGT:	SGGB_0240(dexB)

SMB:	smi_1761(dexB)

SOR:

SOR_1664

STK:	STP_1493(dexB)

STB:	SGPB_0183(dexB.1) SGPB_1524(dexB.2)

SCP:	HMPREF0833_11160(dexB)

SCF:	Spaf_1727(dexB)

SSR:	SALIVB_0714(dexB)

STF:	Ssal_00770(dexB)

STJ:	SALIVA_1406(dexB)

STRS:

SSAL8618_06900

SSAH:

HSISS4_01244

STD:	SPPN_02365

SMN:	SMA_0221(dexB)

SIE:	SCIM_0234(amyA)

SIB:	SIR_0292(dexB)

SIU:	SII_0272(dexB)

SCG:	SCI_0286(dexB)

SCON:

SCRE_0266(dexB)

SCOS:

SCR2_0266(dexB)

SIK:

K710_0290

SIQ:	DQ08_01395

SIO:	DW64_01390

SIZ:	SI82_01680

SLU:

KE3_0151

SIG:	N596_01565 N596_05580

SIP:	N597_03255 N597_07435

STV:	V470_08155

STRA:

ATM98_05210

STRN:

SNAG_1607(dexB)

SSOB:

DK181_06630

SRQ:	SR187_3115

SKI:	D7D50_05025 D7D50_08915

SRAT:

FY406_01230

SGW:	D7D53_00565

SPLR:

C0J00_01255

STRG:

SRT_12640

SVB:	NCTC12167_01301(dexB)

SMEN:

SAMEA4412692_1786(dexB)

SFER:

NCTC12278_00348(dexB.1)

SCAI:

NCTC12191_00308(dexB)

SPSU:

NCTC13786_00912(dexB)

SPOC:

NCTC10925_00310(dexB)

SPAB:

KQ224_10280

SAUP:

NCTC3168_01100(dexB)

SURN:

NCTC13766_01904(dexB)

SACO:

SAME_02132(dexB)

SVF:	NCTC3166_01648(dexB)

SOS:	INT76_03030

STOY:

STYK_16480(dexB)

SRUM:

GPZ88_05525

SACY:

O6R09_00915

SRUN:

LPB404_08825

FPEN:

KIW23_02365

LJO:

LJ_0220

LJF:	FI9785_295

LJH:

LJP_0224

LJN:	T285_01215

LAC:

LBA0264

LAD:

LA14_0257

LAF:

SD55_0255

LDE:	LDBND_0166

LGA:

LGAS_0222

LCR:	LCRIS_00267(dexB)

LAI:	LAC30SC_01225

LAY:	LAB52_01300

LAE:

LBAT_0324

LJE:	BUE77_01150

LAMY:

B1745_07680

LPW:	LpgJCM5343_02230

LKL:	DKL58_08705

LTA:	H1A07_01185

LUU:	H4B44_01655

LPAI:

GYM71_09605

LIQ:	KBW87_04550

LMUL:

PUW59_08730

LCZ:	LCAZH_0927

LCS:

LCBD_1127

LCE:

LC2W_1135

LCW:	BN194_11190(dexB)

LCL:	LOCK919_1132

LPI:	LBPG_00158

LCB:	LCABL_11470(dexB)

LCX:	LCA12A_2271 LCA12A_2272

LPL:	lp_3641(dexB)

LPJ:	JDM1_2910(dexB)

LPS:	LPST_C2972(dexB)

LPB:	SH83_15105

LPG:	BB562_16130

LRM:	LRC_04560(amyA)

LAGL:

BEN83_00700

LMUR:

CPS94_00640

PDM:	ADU72_1435

PIO:	PI20285_07980

LALW:

BTM29_09420

LALI:

LA20249_03575

LSA:	LCA_1791(dexB)

LCV:	FBA2_00790

LAH:	LA20533_04410

LHB:	D1010_04035

LDX:	LH506_08165

LGC:	A9176_05765

LPSE:

FGL85_08960

EFA:

EF1348

EFL:	EF62_1800(dexA)

EFI:	OG1RF_11137(dexB)

EFD:	EFD32_1161

EFS:	EFS1_1168(dexB)

EFN:	DENG_01508(dexB)

EFQ:

DR75_423

ENE:

ENT_07910

EFC:	EFAU004_00367(dexB)

EFAU:

EFAU085_00303(dexB)

EFU:	HMPREF0351_10376(dexB)

EFM:

M7W_543

EFT:	M395_01720

EHR:

EHR_06255

EMU:

EMQU_0344

EDU:

LIU_13295

ESS:	ATZ33_14910

ETH:	CK496_01500 CK496_06870

EAV:	EH197_08405

ESG:	EsVE80_00510(dexB) EsVE80_19590

ELAC:

I4Q40_01635 I4Q40_01940

ECEC:

NCTC12421_01718(dexB)

ERAF:

J9537_01865 J9537_15420

EDS:	PML78_07390 PML78_10690

EMS:	P3T75_02890 P3T75_13315

THL:	TEH_10110(dexB) TEH_12170(dexB)

TEY:	GLW17_00105 GLW17_03385

VPI:	BW732_03140

VAC:	E4Z98_01880

VAO:	FA707_01675

VCP:	H9L18_10315

VHY:	G7082_10495

VFV:	K5K99_02875 K5K99_07305

VLU:	M2919_01575

AUI:	APT62_04880

AVS:	AWM76_05355

GSG:	CYJ72_002955

CRN:	CAR_c13890(dexB)

CML:	BN424_2537(malL)

CAW:	Q783_06435

CARC:

NY10_742

CDJ:	BFC22_00250 BFC22_05115

CARN:

FPV25_00875

CVD:	LHA31_12070

MARR:

BKP56_11790

JEP:	BW721_09810 BW721_10440

JEH:	EJN90_04350 EJN90_04855

JAR:	G7057_03530 G7057_04085

JPO:	G7058_03970

DPM:	FNV33_08865

DINC:

QNK01_10230

CBZ:

Cbs_0735

CBEI:

LF65_00808

CSR:	Cspa_c49840(malL2)

CLT:	CM240_0329(dexB)

CDY:	F3K33_04015

CNN:	CNEO_1183(malL)

CGEL:

psyc5s11_06510(dexB)

FSA:	C5Q98_04770 C5Q98_04775

CCOM:

I6K69_08480

CSH:	Closa_0945

RTO:

RTO_13830

RGN:	RGna_08505

DLO:	K5I24_08830

ERE:	EUBREC_0892

ERT:

EUR_19490

ERA:

ERE_22030

VGU:	HYG85_08200

APR:

Apre_0243

MHG:

MHY_17140

MFUN:

GXM21_03345

EHN:	H9Q80_07620

MAMP:

MAMA39_02260

MMAH:

O3I44_00980

SHJ:	SHELI_v1c09330(dexB)

STAB:

STABA_v1c04770

MOB:	NCTC10112_00220

MBJ:	KQ51_01502(dexB)

TBZ:	BK011_02260

ACIT:

HPK19_08880

» show all

Reference

Authors

Ohya, T., Sawai, T., Uemura, S. and Abe, K.

Title

Some catalytic properties of an exo-1,6-alpha-glucosidase (glucodextranase) from Arthrobacter globiformis I42.

Journal

Agric Biol Chem 42:571-577 (1978)

Reference

Authors

Sawai, T., Yamaki, T. and Ohya, T.

Title

Preparation and some properties of Arthrobacter globiformis exo-1,6-alpha-glucosidase.

Journal

Agric Biol Chem 40:1293-1299 (1976)

Reference

3 [PMID:4356399]

Authors

Walker GJ, Pulkownik A.

Title

Degradation of dextrans by an alpha-1,6-glucan glucohydrolase from Streptococcus mitis.

Journal

Carbohydr Res 29:1-14 (1973)
DOI:10.1016/S0008-6215(00)82066-2

Other DBs

ExplorEnz - The Enzyme Database:

3.2.1.70

IUBMB Enzyme Nomenclature:

3.2.1.70

ExPASy - ENZYME nomenclature database:

3.2.1.70

BRENDA, the Enzyme Database:

3.2.1.70

CAS:	37288-48-5

DBGET integrated database retrieval system