KEGG ENZYME: 3.4.19.11

ENZYME: 3.4.19.11

Entry

EC 3.4.19.11                Enzyme

Name

gamma-D-glutamyl-meso-diaminopimelate peptidase;
endopeptidase I;
gamma-D-glutamyldiaminopimelate endopeptidase;
gamma-D-glutamyl-L-meso-diaminopimelate peptidoglycan hydrolase;
gamma-glutamyl-L-meso-diaminopimelyl endopeptidase;
gamma-D-glutamyl-meso-diaminopimelate endopeptidase;
gamma-D-glutamyl-meso-diaminopimelic peptidoglycan hydrolase;
gamma-D-glutamyl-meso-diaminopimelic endopeptidase;
gamma-D-glutamyl-meso-D-aminopimelic endopeptidase

Class

Hydrolases;
Acting on peptide bonds (peptidases);
Omega peptidases

Reaction(IUBMB)

Hydrolysis of gamma-D-glutamyl bonds to the L-terminus (position 7) of meso-diaminopimelic acid (meso-A2pm) in 7-(L-Ala-gamma-D-Glu)-meso-A2pm and 7-(L-Ala-gamma-D-Glu)-7-(D-Ala)-meso-A2pm. It is required that the D-terminal amino and carboxy groups of meso-A2pm are unsubstituted

Comment

A 45-kDa metallopeptidase from Bacillus sphaericus, the substrates being components of the bacterial spore wall. A member of peptidase family M14 (carboxypeptidase A family). Endopeptidase II has similar activity, but differs in cellular location, molecular mass and catalytic mechanism [3]

History

EC 3.4.19.11 created 1996

Orthology

K01308

g-D-glutamyl-meso-diaminopimelate peptidase

Genes

SMUC:

JL100_032840

BSU:	BSU24830(yqgT)

BSR:

I33_2565

BSL:

A7A1_3558

BSH:	BSU6051_24830(yqgT)

BSY:	I653_11935

BSUT:

BSUB_02660(yqgT)

BSUL:

BSUA_02660(yqgT)

BSUS:

Q433_13590

BSO:	BSNT_08925(yqgT)

BSN:	BSn5_02970

BSQ:	B657_24830(yqgT)

BSX:	C663_2367(yqgT)

BSP:	U712_12130

BSS:	BSUW23_12300(yqgT)

BST:

GYO_2747

BIT:	BIS30_02155

BLI:	BL01578(yqgT)

BLD:	BLi02657(yqgT)

BLH:	BaLi_c27390(yqgT)

BAY:	RBAM_023160

BAQ:	BACAU_2329(yqgT)

BYA:	BANAU_2468(yqgT)

BAMP:

B938_11970

BQY:	MUS_2780(yqgT)

BAML:

BAM5036_2238(yqgT)

BAMA:

RBAU_2451(yqgT)

BAMN:

BASU_2241(yqgT)

BAMB:

BAPNAU_1267(yqgT)

BAMT:

AJ82_13115

BAMY:

V529_25900(yqgT)

BMP:	NG74_02423

BAO:	BAMF_2385(yqgT)

BAZ:	BAMTA208_12765(yqgT)

BQL:	LL3_02681(yqgT)

BXH:	BAXH7_02605(yqgT)

BAMI:

KSO_007800

BAMC:

U471_23960

BAMF:

U722_12600

BSIA:

CWD84_09365

BAE:	BATR1942_10730

BVM:	B9C48_11780

BSON:

S101395_01865(yqgT)

BHT:	DIC78_19025

BMOJ:

HC660_23650(yqgT)

BTEQ:

G4P54_13000

BIQ:	AN935_12295

BSTR:

QI003_15810(yqgT)

BPU:

BPUM_2213

BPUM:

BW16_11990

BPUS:

UP12_11240

BIF:	N288_18105

BMET:

BMMGA3_11660

BSM:	BSM4216_2556

BGY:

BGLY_2933

BWH:	A9C19_06315 A9C19_16115

BXI:	BK049_15860

BALT:

CFN77_11840

BAER:

BAE_18980

BSAF:

BSL056_12260

BFD:	NCTC4823_00893(yggT)

BSHI:

LGQ02_08300

BBAD:

K7T73_18195

BCAB:

EFK13_12630

BRY:	M0696_12325

BJS:

MY9_2507

BACI:

B1NLA3E_03690 B1NLA3E_15825

GST:	HW35_11310

BACW:

QR42_11185

BACP:

SB24_17140

BACB:

OY17_14855

BACY:

QF06_10610

BACL:

BS34A_27240

BALM:

BsLM_2441

BACS:

AUL54_18260

BACQ:

DOE78_05555 DOE78_17115

BACA:

FAY30_06860 FAY30_12745 FAY30_16970

BAQU:

K6959_10945

BZH:	NF868_10075

BHAI:

KJK41_15225

BCAO:

LC087_07450

BAEI:

RE735_08630

BCO:	Bcell_1828

BHK:	B4U37_05840 B4U37_14900

BCOH:

BC6307_15195

BCIR:

C2I06_09705 C2I06_24490

NTX:	NQZ71_08465 NQZ71_18075

BMQ:

BMQ_4500

BMD:

BMD_4486

BMEG:

BG04_1492

BEO:

BEH_19785

BFX:	BC359_05230

PKS:	IE339_18850

BHA:

BH1603

BKW:	BkAM31D_10740

BGI:	BGM20_06190

BPF:	BpOF4_05905 BpOF4_10280(yggT) BpOF4_15185(yggT)

BON:	A361_20830

BKO:	CKF48_17930

CGOT:

J1899_06655 J1899_15080

CSUA:

IM538_03815 IM538_17145

CFIR:

NAF01_18530

CSOA:

LIS82_19285

CSPG:

LS684_04720 LS684_14470 LS684_18745

CPSS:

M5V91_00490

BDA:	FSZ17_16005

OIH:

OB1731

GKA:

GK2441

GTE:	GTCCBUS3UF5_27550

GTK:	GT3570_11845

GTM:	GT3921_07260

GLI:	GLN3_05120

BCAL:

CWI35_16190

GTN:

GTNG_2380

GWC:	GWCH70_2377

GYC:	GYMC61_0196

GYA:	GYMC52_2474

GCT:	GC56T3_1046

GMC:	GY4MC1_1123

GGH:	GHH_c25180(yqgT)

GJF:	M493_12675

GEA:	GARCT_02422

GEL:	IB49_04015

GSE:	GT50_03590

GSR:	GS3922_03945

GEJ:	A0V43_10105

GZA:	IC807_08365

GTH:	Geoth_1234

PTL:	AOT13_16695

PTB:	DER53_16675

PCAL:

BV455_02897

PARG:

PspKH34_10850(yqgT)

AFL:	Aflv_0897(yqgT)

AGN:	AFK25_10070

ANM:	GFC28_3727

AAMY:

GFC30_2636

ANL:	GFC29_1706

AND:	GRQ40_12970

ACAI:

ISX45_10400

AXL:

AXY_07970

LSP:

Bsph_4703

LGY:	T479_23365

LFU:	HR49_00440

LYS:	LBYS11_22640

LYB:	C3943_26590

LYG:	C1N55_19965

LPAK:

GDS87_23935

LYC:	FH508_0023445

LCAP:

ICJ70_00790

LYP:	MTP04_06050 MTP04_06060 MTP04_38530

LIU:	OU989_22085

HHD:	HBHAL_2017(yqgT)

HMN:	HM131_16255

HLI:

HLI_06400

HNZ:	P9989_05790

HSAN:

MUN89_17605

HSHI:

MUO14_19450

TAP:	GZ22_08015

TAID:

KS242_09110

VIR:	X953_11210

VHL:	BME96_10060

VIL:	CFK37_15145

VNE:	CFK40_11375

VIM:	GWK91_05915

LAO:	AOX59_04395

FPN:	ABE65_014025

FAR:	ABE41_012790 ABE41_015250 ABE41_017080

FEC:	QNH15_15255

APAK:

AP3564_18115

ACOP:

RI196_12620

BSJ:	UP17_04695 UP17_16445 UP17_22615

BMUR:

ABE28_004870 ABE28_015180 ABE28_021180

PBUT:

DTO10_03235 DTO10_09035 DTO10_10390 DTO10_17165

PASA:

BAOM_0715 BAOM_0842 BAOM_3771 BAOM_4721

PPSR:

I6J18_11505

PFRI:

L8956_05075 L8956_17045 L8956_24060

BTHV:

CQJ30_06180 CQJ30_12205

PSYH:

D0S48_05760

PSYB:

KD050_10600 KD050_15290

PRD:	F7984_01025 F7984_13540

GRC:	GI584_07155

GCS:	MUN88_21185

GSM:	MUN87_20435

POF:	GS400_10455 GS400_11465 GS400_13400

PCHU:

QNI29_06935 QNI29_14005 QNI29_14415

NMK:	CHR53_01395 CHR53_07575

NTM:	BTDUT50_11580

NDT:	L1999_05605 L1999_21535

NCM:	QNK12_05830 QNK12_22990

NNV:	QNH39_13380

MEKU:

HUW50_00865 HUW50_12440

MSEM:

GMB29_03650 GMB29_19605

MDG:	K8L98_17605

MLIT:

KDJ21_013220

AIA:	AWH56_019710 AWH56_025175

BLEN:

NCTC4824_03606(yggT)

SEDD:

ERJ70_13615

BVQ:	FHE72_14910

RMF:	D5E69_14785

RAZ:	U9J35_15200

BVJ:	I5776_03255

BSE:

Bsel_0990

MCUI:

G8O30_07795 G8O30_11700

GAJ:	MY490_07545 MY490_20995

PSUA:

FLK61_33665 FLK61_37900

MJO:	FOF60_04915

MSUT:

LC048_16950

FHL:	OE105_07365

FAF:	OE104_03570 OE104_08900

SFOR:

QNH23_00500

ALKL:

MM271_14190

ALKG:

MOJ78_13590

PHJ:	LC071_03885

DOM:	RRU94_10655

PUK:	PU629_07930

BHUI:

LOK74_16880

PJD:	Pjdr2_2087

GYM:	GYMC10_4636

PPY:

PPE_01674

PPM:	PPSC2_08820(yqgT)

PPO:	PPM_1677(yqgT)

PPOL:

X809_09070

PPQ:	PPSQR21_017520

PPOY:

RE92_03480

PMS:	KNP414_01555

PMQ:	PM3016_1862

PMW:

B2K_09460

PTA:	HPL003_16820

PLV:	ERIC2_c11410

PSAB:

PSAB_06205 PSAB_09570

PDU:	PDUR_10910

PBD:	PBOR_12825

PGM:	PGRAT_11750

POD:	PODO_10125

PAEN:

P40081_12555

PAEF:

R50345_10590

PAEQ:

R50912_12135

PSTE:

PSTEL_10865

PAEA:

R70723_11310

PAEE:

R70331_11075

PAEH:

H70357_12705

PAEJ:

H70737_10065

PBJ:	VN24_00655

PIH:	UB51_14470

PRI:	PRIO_1488 PRIO_2513

PSON:

JI735_15525 JI735_21505

PPEO:

ABE82_08910

PNP:	IJ22_05720

POW:	IJ21_36210 IJ21_46690

PXL:	BS614_13885

PYG:	AWM70_03855

PDH:	B9T62_07350

PIB:	BBD41_22250

PCX:	LPB68_10820 LPB68_18330

PKB:	B4V02_16480

PAIH:

ASL14_02565

PVO:	PVOR_24924

PLW:	D5F53_07005

PLEN:

EIM92_16610 EIM92_19240

PPSC:

EHS13_12525 EHS13_22620

PLUT:

EI981_06305 EI981_19565

PALB:

EJC50_23635

PCHI:

PC41400_01055 PC41400_09755

PBK:	Back11_04540 Back11_61420

PPRT:

ET464_08485

PBAC:

HUB98_26910

PRZ:	GZH47_27165

PLYC:

GXP70_20480

PSOP:

KP014_09945 KP014_13405

PTRI:

KDC22_10955

PALO:

E6C60_2803

PCEL:

HUB94_10930 HUB94_23520

PTJ:	JRJ22_05180 JRJ22_09530

PALR:

HGI30_08360

PTHI:

NDS46_21165

PKA:	PQ456_14330

PUI:	PUW25_08615

PMAH:

PTQ21_15225

PAMY:

P9222_27565

PDY:	QJQ58_00945

PMAE:

LMZ02_21890

PWN:	QNH46_09385

PSPN:

L1F29_06455 L1F29_22555

PPOG:

QPK24_08025

PHK:	SK066_09080

PNK:	AASFL403_04740

PPAB:

KET34_11305

PKP:	SK3146_02041

TCO:	Theco_0622 Theco_1646

ANX:	ACH33_05015

ASOC:

CB4_01294

ATHE:

K3F53_13890

COH:	EAV92_03050

COHN:

KCTCHS21_42790 KCTCHS21_48250

CCHL:

FPL14_04805 FPL14_15060

CHEB:

HH215_11800

SACA:

FFV09_12780

AFX:	JZ786_13425

ACUR:

JZ785_25100

EFF:	skT53_19540

SIV:	SSIL_1326 SSIL_2204

SSIL:

SOLI23_07650 SOLI23_11740

SPSY:

AZE41_01010

STHO:

QNH10_03835

RST:	ATY39_14690

PAEK:

D3873_03185

VIJ:	JNUCC6_03670

CTC:

CTC_00595

CTET:

BN906_00618

CBO:

CBO1374

CBA:

CLB_1398

CBH:

CLC_1409

CBY:

CLM_1547

CBL:

CLK_0816

CBB:

CLD_3164

CBI:

CLJ_B1489

CBF:

CLI_1470

CBM:

CBF_1446

CBJ:	H04402_01441

CKL:

CKL_0988

CKR:

CKR_0892

CLJ:	CLJU_c06860

CLB:	Clo1100_4021

CPAS:

Clopa_0912

CPAT:

CLPA_c07870

CPAE:

CPAST_c07870

CAH:	CAETHG_2777

CLD:	CLSPO_c14170

CBUT:

ATN24_19415

CTYK:

CTK_C06910

CEU:	A7L45_01585

CARG:

RSJ17_19880

CCOH:

SAMEA4530647_0497

CTAG:

LL095_01410

CTHD:

CDO33_05220

HHW:	NCTC503_02215

CRS:	FQB35_10765

CPRF:

K7H06_11505 K7H06_11855

CRAS:

KVH43_09075

CTH:

Cthe_2387

CTX:	Clo1313_0017

CCL:	Clocl_4150

HSC:

HVS_15630

CCE:

Ccel_3421

RHER:

EHE19_018700

RPAY:

P0092_21570

CSS:	Cst_c15070

CSD:

Clst_1455

CCEL:

CCDG5_0891 CCDG5_1738

EHA:	Ethha_0917

RUM:

CK1_07060

RUJ:	E5Z56_04610

SMAN:

C12CBH8_01320

ACOL:

K5I23_06925

TMEL:

NOG13_07380

PETR:

QKW49_14830

PALM:

RBG61_05900

CAPR:

EQM14_14540

CFEM:

HCR03_10680

STH:

STH1567

SGY:

Sgly_0915

DOR:	Desor_1724

DMI:	Desmer_1675

DED:	DHBDCA_p2953

DEC:	DCF50_p2957

DRS:	DEHRE_14625

HCV:	FTV88_2267

PROM:

QO263_01450

BPRM:

CL3_29340

BFI:

CIY_33400

RHO:	RHOM_09390

RIX:

RO1_39600

RIM:

ROI_27900

RRK:	H8S51_007335

ROB:

CK5_27750

BYL:	A4V09_14680

BHAN:

CGC63_12465

BLAU:

DQQ01_12315

BPRO:

PMF13cell1_02165

BLAB:

EYS05_14950

BLIQ:

INP51_03215 INP51_06935

BLAR:

LC508_13200

BCOC:

BLCOC_12500

BHV:	BLHYD_01770

CSO:

CLS_14600

HSD:

SD1D_1068

LUA:	D4A81_05135

LGG:	QJR73_04965

EHL:

EHLA_3133

WHJ:	H9Q79_04510

STOM:

QU660_03165 QU660_09600

CLE:	Clole_1196 Clole_2076

CEW:	EKH84_08670 EKH84_12550

CBAR:

PATL70BA_2144

VGU:	HYG85_22580

VPY:	HZI73_14060

ETM:	CE91St48_22200

GFE:	Gferi_12090 Gferi_22940

CSPO:

QNI18_00640

TEM:	JW646_15550

TGC:	L0P85_12080

TMY:	TEMA_04430

TEB:

T8CH_2336

THYR:

P4S50_05495

MAS:	Mahau_1993

NTH:	Nther_0658

AAR:	Acear_1489

IPS:	CfP315_0895

PTRH:

RsTaC01_0484

CAD:	Curi_c13250

CAZO:

G3A45_05525

SEDZ:

JYG23_02910

ACIT:

HPK19_01340 HPK19_16765

ALQ:	C7Y71_006740

FLU:	CHH17_03005

» show all

Reference

1 [PMID:849747]

Authors

Arminjon F, Guinand M, Vacheron MJ, Michel G.

Title

Specificity profiles of the membrane-bound gamma-D-glutamyl-(L)meso-diaminopimelateendopeptidase and LD-carboxypeptidase from Bacillus sphaericus 9602.

Journal

Eur J Biochem 73:557-65 (1977)
DOI:10.1111/j.1432-1033.1977.tb11351.x

Reference

2 [PMID:3922755]

Authors

Garnier M, Vacheron MJ, Guinand M, Michel G.

Title

Purification and partial characterization of the extracellular gamma-D-glutamyl-(L)meso-diaminopimelate endopeptidase I, from Bacillus sphaericus NCTC 9602.

Journal

Eur J Biochem 148:539-43 (1985)
DOI:10.1111/j.1432-1033.1985.tb08873.x

Sequence

[ag:CAA49259]

Reference

3 [PMID:8503890]

Authors

Hourdou ML, Guinand M, Vacheron MJ, Michel G, Denoroy L, Duez C, Englebert S, Joris B, Weber G, Ghuysen JM

Title

Characterization of the sporulation-related gamma-D-glutamyl-(L)meso-diaminopimelic-acid-hydrolysing peptidase I of Bacillus sphaericus NCTC 9602 as a member of the metallo(zinc) carboxypeptidase A family. Modular design of the protein.

Journal

Biochem J 292 ( Pt 2):563-70 (1993)
DOI:10.1042/bj2920563

Sequence

[ag:CAA49259]

Other DBs

ExplorEnz - The Enzyme Database:

3.4.19.11

IUBMB Enzyme Nomenclature:

3.4.19.11

ExPASy - ENZYME nomenclature database:

3.4.19.11

BRENDA, the Enzyme Database:

3.4.19.11

CAS:	62572-28-5

DBGET integrated database retrieval system