Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases
Reaction(IUBMB)
Similar to that of papain
Comment
The major proteolytic component of the latex of fig, Ficus glabrata. Cysteine endopeptidases with similar properties are present in other members of the large genus Ficus. In peptidase family C1 (papain family).
History
EC 3.4.22.3 created 1961 as EC 3.4.4.12, transferred 1972 to EC 3.4.22.3
Reference
1
Authors
Liener, I.E. and Friedenson, B.
Title
Ficin.
Journal
Methods Enzymol 19:261-273 (1970)
Reference
2
Authors
Brocklehurst, K., Willenbrock, F. and Salih, E.
Title
Cysteine proteinases.
Journal
In: Neuberger, A. and Brocklehurst, K. (Eds.), New Comprehensive Biochemistry: Hydrolytic Enzymes, Elsevier, Amsterdam, 1987, p. 39-158.