| Entry |
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| Name |
barrierpepsin;
barrier proteinase;
Bar proteinase
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| Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Aspartic endopeptidases
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| Reaction(IUBMB) |
Selective cleavage of -Leu6!Lys- bond in the pheromone alpha-mating factor
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| Comment |
A secreted endopeptidase known from baker's yeast (Saccharomyces cerevisiae). In peptidase family A1 (pepsin A family)
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| History |
EC 3.4.23.35 created 1993
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| Orthology |
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| Genes |
| NCS: | NCAS_0A12460(NCAS0A12460) |
| NDI: | NDAI_0B01720(NDAI0B01720) |
| TBL: | TBLA_0D04580(TBLA0D04580) |
| TDL: | TDEL_0H02650(TDEL0H02650) |
| KNG: | KNAG_0H02760(KNAG0H02760) |
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| Reference |
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| Authors |
MacKay VL, Welch SK, Insley MY, Manney TR, Holly J, Saari GC, Parker ML |
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| Title |
The Saccharomyces cerevisiae BAR1 gene encodes an exported protein with homology to pepsin. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
MacKay VL, Armstrong J, Yip C, Welch S, Walker K, Osborn S, Sheppard P, Forstrom J. |
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| Title |
Characterization of the Bar proteinase, an extracellular enzyme from the yeast Saccharomyces cerevisiae. |
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| Journal |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 3.4.23.35 |
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