neurolysin;
neurotensin endopeptidase;
endopeptidase 24.16;
endo-oligopeptidase B (proline-endopeptidase)
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
Reaction(IUBMB)
Preferential cleavage in neurotensin: Pro10!Tyr
Comment
No absolute requirement for a prolyl bond: the enzyme acts on some peptides, such as dynorphin 1-8, that do not contain proline, and does not act on some others that do. In peptidase family M3 (thimet oligopeptidase family)