KEGG   ENZYME: 3.4.24.53
Entry
EC 3.4.24.53                Enzyme                                 
Name
trimerelysin II;
Trimeresurus metalloendopeptidase II;
proteinase H2;
H2-proteinase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
Reaction(IUBMB)
Cleavage of Asn3!Gln, His10!Leu and Ala14!Leu in the insulin B chain, and the bond Z-Gly-Pro!Leu-Gly-Pro in a small molecule substrate of microbial collagenase
Comment
A 24 kDa nonhemorrhagic endopeptidase from the venom of the habu snake (Trimeresurus flavoviridis). In peptidase family M12 (astacin family)
History
EC 3.4.24.53 created 1992
Reference
1  [PMID:4984550]
  Authors
Takahashi T, Ohsaka A.
  Title
Purification and characterization of a proteinase in the venom of Trimeresurus flavoviridis. Complete separation of the enzyme from hemorrhagic activity.
  Journal
Biochim Biophys Acta 198:293-307 (1970)
DOI:10.1016/0005-2744(70)90062-8
Reference
2  [PMID:2777746]
  Authors
Takeya H, Arakawa M, Miyata T, Iwanaga S, Omori-Satoh T.
  Title
Primary structure of H2-proteinase, a non-hemorrhagic metalloproteinase, isolated from the venom of the habu snake, Trimeresurus flavoviridis.
  Journal
J Biochem (Tokyo) 106:151-7 (1989)
DOI:10.1093/oxfordjournals.jbchem.a122805
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.53
IUBMB Enzyme Nomenclature: 3.4.24.53
ExPASy - ENZYME nomenclature database: 3.4.24.53
BRENDA, the Enzyme Database: 3.4.24.53
CAS: 151125-15-4

  All links  
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (2)   
   PDBSTR (3)   
3D Structure (2)   
   PDB (2)   
Protein domain (8)   
   InterPro (7)   
   PROSITE(DOC) (1)   
All databases (17)   

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