Entry |
|
Name |
2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase;
compound B hydrolase;
alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase
|
Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
|
Sysname |
2-(hydroxymethyl)-3-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)
|
Reaction(IUBMB) |
2-(hydroxymethyl)-3-(acetamidomethylene)succinate + 2 H2O = acetate + 2-(hydroxymethyl)-4-oxobutanoate + NH3 + CO2 [RN: R04397]
|
Reaction(KEGG) |
|
Substrate |
2-(hydroxymethyl)-3-(acetamidomethylene)succinate [CPD: C04690];
H2O [CPD: C00001]
|
Product |
|
Comment |
Involved in the degradation of pyridoxin by Pseudomonas and Arthrobacter.
|
History |
EC 3.5.1.66 created 1989
|
Pathway |
|
Reference |
|
Authors |
Huynh MS, Snell EE. |
Title |
Enzymes of vitamin B6 degradation. Purification and properties of two N-acetylamidohydrolases. |
Journal |
J Biol Chem 260:2379-83 (1985) |
Other DBs |
ExplorEnz - The Enzyme Database: | 3.5.1.66 |
ExPASy - ENZYME nomenclature database: | 3.5.1.66 |
UM-BBD (Biocatalysis/Biodegradation Database): | 3.5.1.66 |
|