| Entry |
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| Name |
phosphogluconate dehydratase;
6-phosphogluconate dehydratase;
6-phosphogluconic dehydrase;
gluconate-6-phosphate dehydratase;
gluconate 6-phosphate dehydratase;
6-phosphogluconate dehydrase;
6-phospho-D-gluconate hydro-lyase
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| Class |
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
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| Sysname |
6-phospho-D-gluconate hydro-lyase (2-dehydro-3-deoxy-6-phospho-D-gluconate-forming)
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| Reaction(IUBMB) |
6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O [RN: R02036]
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| Reaction(KEGG) |
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| Substrate |
6-phospho-D-gluconate [CPD: C00345]
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| Product |
2-dehydro-3-deoxy-6-phospho-D-gluconate [CPD: C04442];
H2O [CPD: C00001]
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| History |
EC 4.2.1.12 created 1961
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| Pathway |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K01690 | phosphogluconate dehydratase |
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| Genes |
| ECOO: | ECRM13514_2359(edd) |
| ECOH: | ECRM13516_2262(edd) |
| EDJ: | ECDH1ME8569_1797(edd) |
| ECOI: | ECOPMV1_01944(ilvD_1) |
| REE: | electrica_01875(edd) |
| CLAP: | NCTC11466_01776(ilvD_1) |
| KIE: | NCTC12125_00945(ilvD_1) |
| AHN: | NCTC12129_01992(edd) |
| PSHI: | SAMEA2665130_1207(ilvD_2) |
| YPI: | YpsIP31758_1476(edd) |
| SFG: | AV650_00940 AV650_27780 |
| SFJ: | SAMEA4384070_4459(ilvD_1) |
| SOF: | NCTC11214_02118(ilvD_2) |
| PHEI: | NCTC12003_00430(ilvD_1) |
| PRJ: | NCTC6933_00498(ilvD_1) |
| LRI: | NCTC12151_03548(ilvD_2) |
| PAET: | NCTC13378_01177(ilvD_1) |
| XFU: | XFF4834R_chr21730(edd) |
| XPH: | XppCFBP6546_01915(XppCFBP6546P_01915) |
| VAU: | VANGNB10_cI1775(edd) |
| VPL: | SA104470976_02453(edd) |
| PPUD: | DW66_0998 DW66_1323 |
| PPRC: | PFLCHA0_c46970(edd) |
| PMUD: | NCTC8068_04136(ilvD_2) |
| PFW: | PF1751_v1c44560(edd) |
| PTAE: | NCTC10697_03372(ilvD_4) |
| PPHN: | HU825_01920 HU825_17015 |
| PSZ: | PSTAB_2342 PSTAB_3472 |
| PSR: | PSTAA_2552 PSTAA_3596 |
| PSC: | A458_13000 A458_14105 |
| PSH: | Psest_0849 Psest_1892 |
| PSTU: | UIB01_08985 UIB01_17790 |
| PSED: | DM292_01680 DM292_06620 |
| PCHL: | LLJ08_07245(edd) LLJ08_08430(edd) |
| PKG: | LW136_13730(edd) LW136_15100(edd) |
| SDEG: | GOM96_04165 GOM96_07300 |
| AVN: | Avin_15680(edd-1) Avin_27280(edd-2) |
| AVL: | AvCA_15680(edd-1) AvCA_27280(edd-2) |
| AVD: | AvCA6_15680(edd-1) AvCA6_27280(edd-2) |
| ACX: | Achr_22350(edd-2) Achr_27090(edd-1) |
| SCAA: | TUM17387_18720(edd) |
| AMAA: | amad1_12160 amad1_12235 amad1_20320 |
| AMAD: | I636_11735 I636_11810 |
| AMAI: | I635_12140 I635_12215 I635_20310 |
| AMAG: | I533_11495 I533_11575 I533_19210 |
| ZAL: | AZF00_05680 AZF00_13050 |
| LLG: | 44548918_01395(ilvD) |
| LJR: | NCTC11533_01590(ilvD) |
| LCJ: | NCTC11976_00048(edd) |
| LWA: | SAMEA4504053_0735(ilvD) |
| LSS: | NCTC12082_00096(ilvD) |
| LANT: | TUM19329_04630(edd) |
| MESL: | KKZ03_10995(edd) KKZ03_12005(edd) |
| WEZ: | IC757_02380 IC757_12070 |
| HAXI: | HAALTHF_42630n(edd) |
| AEL: | NCTC12917_04045(edd) |
| TAU: | Tola_0228 Tola_0777 Tola_1795 |
| ZDF: | AN401_00560 AN401_15810 |
| NMM: | NMBM01240149_0762(edd) |
| NMS: | NMBM01240355_1327(edd) |
| NMQ: | NMBM04240196_0813(edd) |
| NWE: | SAMEA3174300_0206(ilvD_1) |
| NZO: | SAMEA4504057_1621(ilvD_2) |
| NCI: | NCTC10296_00317(ilvD_1) |
| NCZ: | NCTC10294_00842(ilvD_2) |
| NANI: | NCTC12227_00440(ilvD_1) |
| RPJ: | N234_05560 N234_34335 |
| REH: | H16_A1178(edd1) H16_B2567(edd2) |
| CNC: | CNE_1c11240(edd) CNE_2c24770(edd) |
| CUH: | BJN34_06210 BJN34_35125 |
| REU: | Reut_A1081 Reut_B5330 |
| RME: | Rmet_1045(edd) Rmet_5802(edd1) |
| CTI: | RALTA_A1158(edd) RALTA_B2297(edd) |
| CBW: | RR42_m1265 RR42_s3479 |
| CCUP: | BKK81_08710 BKK81_21845 |
| CUP: | BKK80_08020 BKK80_20020 |
| CUU: | BKK79_04120 BKK79_25250 |
| CPAU: | EHF44_17160 EHF44_21725 |
| COX: | E0W60_05980 E0W60_16145 |
| CCAM: | M5D45_05190(edd) M5D45_28925(edd) |
| CCAX: | KZ686_09165(edd) KZ686_19715(edd) |
| CUK: | KB879_05885(edd) KB879_17730(edd) |
| CNAN: | A2G96_06910 A2G96_31050 |
| BPM: | BURPS1710b_3442(edd) |
| BPL: | BURPS1106A_3442(edd) |
| PPK: | U875_18155 U875_19490 |
| PPNO: | DA70_10665 DA70_12180 |
| PPNM: | LV28_18520 LV28_20395 |
| PRB: | X636_14695 X636_15965 |
| PPUL: | RO07_12815 RO07_14735 |
| PSPU: | NA29_08875 NA29_22450 |
| PAPI: | SG18_13130 SG18_14560 |
| PVE: | UC34_04575 UC34_05875 |
| POX: | MB84_09020 MB84_10290 |
| PFG: | AB870_15570 AB870_16900 |
| PNR: | AT302_01210 AT302_12880 |
| PAND: | DRB87_04135 DRB87_05275 |
| PFIB: | PI93_004175 PI93_022380 |
| PCOM: | NTU39_04915(edd) NTU39_06785(edd) |
| PLG: | NCTC10937_01160(ilvD_1) |
| BUO: | BRPE64_ACDS23150(edd) |
| IDC: | LRM40_05070(edd) LRM40_06180(edd) |
| RGU: | A4W93_04310 A4W93_19705 |
| MHUA: | MCHK_0197 MCHK_8396(edd) |
| SAME: | SAMCFNEI73_Ch0706(edd) |
| ATF: | Ach5_05220 Ach5_51810(edd) |
| ASAL: | CFBP5507_01210(edd) |
| RPUS: | CFBP5875_01205(edd) |
| ALEG: | CFBP4996_01160(edd) |
| REC: | RHECIAT_CH0000783(edd) |
| RTR: | RTCIAT899_CH03515(edd) |
| RLW: | RlegWSM1455_01870(edd) |
| NGL: | RG1141_CH02860 RG1141_PA11220 |
| BHS: | BM1374165_00371(edd) |
| BTX: | BM1374166_00563(edd) |
| BEZ: | NCTC12898_00243(ilvD_1) |
| MTUN: | MTUNDRAET4_0693(edd) |
| DNP: | N8A98_01235(edd) N8A98_04660(edd) |
| MAAD: | AZF01_10575 AZF01_15070 |
| BVY: | NCTC9239_00348(ilvD_1) |
| TSV: | DSM104635_03657(edd) |
| PPIC: | PhaeoP14_02561(edd) |
| LMD: | METH_14850 METH_16225 |
| SINL: | DSM14862_02667(edd) |
| SPSE: | SULPSESMR1_01002(edd) |
| RMM: | ROSMUCSMR3_02838(edd) |
| AHT: | ANTHELSMS3_03480(edd) |
| LVS: | LOKVESSMR4R_01667(edd) |
| NPN: | JI59_04850 JI59_14105 |
| SPHM: | G432_09410 G432_16645 |
| SINB: | SIDU_04925 SIDU_16600 |
| AAY: | WYH_01517(edd_1) WYH_02547(edd_2) |
| CNA: | AB433_02920 AB433_14935 |
| ERY: | CP97_04950 CP97_05745 |
| RAP: | RHOA_0584(edd) RHOA_PA0017(edd) |
| NGU: | QN315_00475(edd) QN315_09530(edd) |
| ECOG: | FIV45_02280 FIV45_02325 |
| HPO: | HMPREF4655_21289(edd) |
| HPX: | HMPREF0462_1112(edd) |
| PACO: | AACT_0289(edd1) AACT_1908(edd2) |
| NAQU: | ENKNEFLB_00897(edd) |
| FRE: | Franean1_7021 Franean1_7067 |
| BALA: | DSM104299_00924(edd) |
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| Reference |
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| Authors |
MELOCHE HP, WOOD WA. |
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| Title |
THE MECHANISM OF 6-PHOSPHOGLUCONIC DEHYDRASE. |
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| Journal |
J Biol Chem 239:3505-10 (1964) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.2.1.12 |
| ExPASy - ENZYME nomenclature database: | 4.2.1.12 |
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