| Entry |
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| Name |
(+)-caryolan-1-ol synthase;
GcoA
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| Class |
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
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| Sysname |
(+)-beta-caryophyllene hydrolase [cyclizing, (+)-caryolan-1-ol-forming]
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| Reaction(IUBMB) |
(+)-beta-caryophyllene + H2O = (+)-caryolan-1-ol [RN: R09835]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
(+)-caryolan-1-ol [CPD: C19974]
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| Comment |
A multifunctional enzyme which also forms (+)-beta-caryophyllene from farnesyl diphosphate [EC 4.2.3.89, (+)-beta-caryophyllene synthase].
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| History |
EC 4.2.1.138 created 2011 as EC 3.7.1.15, transferred 2013 to EC 4.2.1.138
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| Pathway |
| ec00909 | Sesquiterpenoid and triterpenoid biosynthesis |
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| Orthology |
| K18111 | (+)-beta-caryophyllene/(+)-caryolan-1-ol synthase |
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| Genes |
| NTC: | KHQ06_23155 KHQ06_27360 KHQ06_31745 |
» show all
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| Reference |
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| Authors |
Nakano C, Horinouchi S, Ohnishi Y |
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| Title |
Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 4.2.1.138 |
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