| Entry |
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| Name |
kievitone hydratase;
KHase;
kievitone-hydrate hydro-lyase
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| Class |
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
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| Sysname |
kievitone-hydrate hydro-lyase (kievitone-forming)
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| Reaction(IUBMB) |
kievitone hydrate = kievitone + H2O [RN: R03622]
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| Reaction(KEGG) |
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| Substrate |
kievitone hydrate [CPD: C02549]
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| Product |
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| Comment |
The enzyme from Fusarium sp. hydrates the methylbutenyl sidechain of the isoflavonoid phytoalexins, thus reducing their toxicity.
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| History |
EC 4.2.1.95 created 1992
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| Orthology |
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| Genes |
| NHE: | NECHADRAFT_34615 NECHADRAFT_37099 NECHADRAFT_51190 NECHADRAFT_75707 |
| FFC: | NCS54_00187100 NCS54_00465000 NCS54_01288400 |
| FKR: | NCS57_00185300 NCS57_00470400 |
| CHIG: | CH63R_09559 CH63R_12172 |
| AOR: | AO090038000081 AO090701000464 |
| AFV: | AFLA_004984 AFLA_012350 |
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| Reference |
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| Authors |
Turbek CS, Li DX, Choi GH, Schardl CL, Smith DA |
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| Title |
Induction and purification of kievitone hydratase from Fusarium solani f. sp. phaseoli. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.2.1.95 |
| ExPASy - ENZYME nomenclature database: | 4.2.1.95 |
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