| Entry |
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| Name |
anhydrosialidase;
anhydroneuraminidase;
sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing);
sialidase L
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| Class |
Lyases;
Carbon-oxygen lyases;
Acting on polysaccharides
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| Sysname |
glycoconjugate sialyl-lyase (2,7-cyclizing)
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| Reaction(IUBMB) |
Elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate
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| Comment |
Also acts on N-glycolylneuraminate glycosides. cf. EC 3.2.1.18 (exo-alpha-sialidase) and EC 3.2.1.129 (endo-alpha-sialidase).
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| History |
EC 4.2.2.15 created 1992 as EC 3.2.1.138, transferred 2003 to EC 4.2.2.15
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| Reference |
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| Authors |
Li YT, Nakagawa H, Ross SA, Hansson GC, Li SC. |
|---|
| Title |
A novel sialidase which releases 2,7-anhydro-alpha-N-acetylneuraminic acid from sialoglycoconjugates. |
|---|
| Journal |
J Biol Chem 265:21629-33 (1990) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.2.2.15 |
| ExPASy - ENZYME nomenclature database: | 4.2.2.15 |
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