KEGG   ENZYME: 4.2.3.137
Entry
EC 4.2.3.137                Enzyme                                 
Name
(E)-2-epi-beta-caryophyllene synthase;
2-epi-(E)-beta-caryophyllene synthase;
SmMTPSL26
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (E)-2-epi-beta-caryophyllene-forming)
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (E)-2-epi-beta-caryophyllene + diphosphate [RN:R10273]
Reaction(KEGG)
R10273
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
(E)-2-epi-beta-caryophyllene [CPD:C20478];
diphosphate [CPD:C00013]
Comment
Isolated from the plant Selaginella moellendorfii. The enzyme also gives two other sesquiterpenoids.
History
EC 4.2.3.137 created 2012
Pathway
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K18112  (E)-2-epi-beta-caryophyllene synthase
Genes
SMOSELMODRAFT_414571 SELMODRAFT_414574
Reference
1  [PMID:22908266]
  Authors
Li G, Kollner TG, Yin Y, Jiang Y, Chen H, Xu Y, Gershenzon J, Pichersky E, Chen F
  Title
Nonseed plant Selaginella moellendorffi [corrected] has both seed plant and microbial types of terpene synthases.
  Journal
Proc Natl Acad Sci U S A 109:14711-5 (2012)
DOI:10.1073/pnas.1204300109
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.137
IUBMB Enzyme Nomenclature: 4.2.3.137
ExPASy - ENZYME nomenclature database: 4.2.3.137
BRENDA, the Enzyme Database: 4.2.3.137

DBGET integrated database retrieval system