Entry
Name
cis-abienol synthase;
Z-abienol synthase;
CAS;
ABS
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(13E)-8alpha-hydroxylabd-13-en-15-yl-diphosphate-lyase (cis-abienol-forming)
Reaction(IUBMB)
(13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate = cis-abienol + diphosphate [RN:
R10276 ]
Reaction(KEGG)
Substrate
(13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate [CPD:
C20270 ]
Product
Comment
Isolated from the plants Abies balsamea (balsam fir) [1] and Nicotiana tabacum (tobacco) [2].
History
EC 4.2.3.140 created 2012
Pathway
ec01110 Biosynthesis of secondary metabolites
Orthology
K20518 copal-8-ol diphosphate hydratase / cis-abienol synthase
Genes
Taxonomy
Reference
Authors
Zerbe P, Chiang A, Yuen M, Hamberger B, Hamberger B, Draper JA, Britton R, Bohlmann J
Title
Bifunctional cis-abienol synthase from Abies balsamea discovered by transcriptome sequencing and its implications for diterpenoid fragrance production.
Journal
Sequence
Reference
Authors
Sallaud C, Giacalone C, Topfer R, Goepfert S, Bakaher N, Rosti S, Tissier A
Title
Characterization of two genes for the biosynthesis of the labdane diterpene Z-abienol in tobacco (Nicotiana tabacum) glandular trichomes.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 4.2.3.140