KEGG   ENZYME: 4.2.3.45
Entry
EC 4.2.3.45                 Enzyme                                 
Name
phyllocladan-16alpha-ol synthase;
PaDC1
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(+)-copalyl-diphosphate diphosphate-lyase (phyllocladan-16alpha-ol-forming)
Reaction(IUBMB)
(+)-copalyl diphosphate + H2O = phyllocladan-16alpha-ol + diphosphate [RN:R09686]
Reaction(KEGG)
R09686
Substrate
(+)-copalyl diphosphate [CPD:C11901];
H2O [CPD:C00001]
Product
phyllocladan-16alpha-ol [CPD:C19817];
diphosphate [CPD:C00013]
Comment
The adjacent gene PaDC2 codes EC 5.5.1.12 copalyl diphosphate synthase.
History
EC 4.2.3.45 created 2009
Pathway
ec00904  Diterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K20514  phyllocladan-16alpha-ol/copalyl diphosphate synthase
Reference
1  [PMID:18391465]
  Authors
Toyomasu T, Niida R, Kenmoku H, Kanno Y, Miura S, Nakano C, Shiono Y, Mitsuhashi W, Toshima H, Oikawa H, Hoshino T, Dairi T, Kato N, Sassa T
  Title
Identification of diterpene biosynthetic gene clusters and functional analysis of labdane-related diterpene cyclases in Phomopsis amygdali.
  Journal
Biosci Biotechnol Biochem 72:1038-47 (2008)
DOI:10.1271/bbb.70790
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.45
IUBMB Enzyme Nomenclature: 4.2.3.45
ExPASy - ENZYME nomenclature database: 4.2.3.45
BRENDA, the Enzyme Database: 4.2.3.45

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