KEGG ENZYME: 4.2.3.47

ENZYME: 4.2.3.47

Entry

EC 4.2.3.47                 Enzyme

Name

beta-farnesene synthase;
farnesene synthase;
terpene synthase 10;
terpene synthase 10-B73;
TPS10

Class

Lyases;
Carbon-oxygen lyases;
Acting on phosphates

Sysname

(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(E)-beta-farnesene-forming]

Reaction(IUBMB)

(2E,6E)-farnesyl diphosphate = (E)-beta-farnesene + diphosphate [RN:R08695]

Reaction(KEGG)

R08695

Substrate

(2E,6E)-farnesyl diphosphate [CPD:C00448]

Product

(E)-beta-farnesene [CPD:C09666];
diphosphate [CPD:C00013]

History

EC 4.2.3.47 created 2010

Pathway

ec00909

Sesquiterpenoid and triterpenoid biosynthesis

ec01110

Biosynthesis of secondary metabolites

Orthology

K12645

epi-isozizaene 5-monooxygenase / beta-farnesene synthase

K14174

beta-farnesene/exo-alpha-bergamotene synthase

K15793

acyclic sesquiterpene synthase

K22064

beta-farnesene synthase

Genes

PVY:	116119561 116136104 116140808

MINC:

123193041 123193184 123218451 123219543

BDI:

100833760

ATS:	109780592 109783760

TDC:	119356231 119356232 119365401 119365402

TAES:

100873133 123041882 123041883 123054327 123190213 123191849

TUA:	125533918 125539513

LPER:

127336238

LRD:

124679046

SBI:	8072328 8080876

ZMA:	100274033 541974 732751

SITA:

101771563

SVS:

117862601

PVIR:

120640652 120683675

PHAI:

112898865

SCO:	SCO5223(SC7E4.20)

SALB:

XNR_1579

SMA:	SAVERM_3031(cyp14)

SHY:

SHJG_6336

SHO:	SHJGH_6097

SDV:	BN159_3154

SALS:

SLNWT_2071

SCI:	B446_24615

SLV:	SLIV_12250

SGU:	SGLAU_22465

SCW:	TU94_21770

SAMB:

SAM23877_5011

SCX:	AS200_17630

SRW:	TUE45_05743

STRF:

ASR50_23825

SLE:	sle_25170(sle_25170)

SPAV:

Spa2297_22090

STRT:

A8713_21095

SGS:	AVL59_06870

STSI:

A4E84_26815

SKY:	D0C37_09630

SALW:

CP975_23795

SGM:	GCM10017557_26710

SCAD:

DN051_14270

SPHW:

NFX46_06120

SLS:	SLINC_5615

SPLU:

LK06_022340

STRD:

NI25_13050

SSIA:

A7J05_12560

SPUN:

BFF78_14830

SALF:

SMD44_05800

SFK:

KY5_5349

SNZ:	DC008_23215

SGE:	DWG14_02916

SRJ:

SRO_2585

SDX:	C4B68_13425

SGD:	ELQ87_13270

SCYA:

EJ357_30820

SAST:

CD934_10765

SNQ:	CP978_22470

SKA:	CP970_14415

SHAW:

CEB94_27440

SGAL:

CP966_24285

SFY:	GFH48_14920

SAQU:

EJC51_32140

SGF:	HEP81_02793

SSEO:

D0Z67_19540

SFUG:

CNQ36_23700

SPAC:

B1H29_12435

SCHA:

CP983_14565

SCOE:

CP976_28740

SSPB:

CP982_27725

SBRO:

GQF42_28700

STUI:

GCM10017668_47530

SCHF:

IPT68_24090

SCYG:

S1361_25900

SFEU:

IM697_37485

SVD:	CP969_25545

SPRA:

CP972_23865

SROI:

IAG44_13190

SXN:	IAG42_11635

SHK:	J2N69_24780

SDD:	D9753_11940

SACT:

DMT42_26025

SLF:	JEQ17_16410

SAOV:

G3H79_11730

SDUR:

M4V62_15475

SRUG:

F0345_20200

SVIO:

HWN34_08575

SCIR:

STRCI_005417

SLON:

LGI35_28880

STEE:

F3L20_05650

SARG:

HKX69_11535

SJN:	RI060_13600

SCYN:

N8I84_26390

SKG:	KJK29_11460

SCOA:

QU709_13405

SFP:	QUY26_12495

SINN:

ABB07_12990

KBU:	Q4V64_34950

» show all

Reference

1 [PMID:19858213]

Authors

Zhao B, Lei L, Vassylyev DG, Lin X, Cane DE, Kelly SL, Yuan H, Lamb DC, Waterman MR

Title

Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site.

Journal

J Biol Chem 284:36711-9 (2009)
DOI:10.1074/jbc.M109.064683

Sequence

[sco:SCO5223]

Reference

2 [PMID:15896363]

Authors

Picaud S, Brodelius M, Brodelius PE

Title

Expression, purification and characterization of recombinant (E)-beta-farnesene synthase from Artemisia annua.

Journal

Phytochemistry 66:961-7 (2005)
DOI:10.1016/j.phytochem.2005.03.027

Reference

3 [PMID:19646721]

Authors

Kollner TG, Gershenzon J, Degenhardt J

Title

Molecular and biochemical evolution of maize terpene synthase 10, an enzyme of indirect defense.

Journal

Phytochemistry 70:1139-45 (2009)
DOI:10.1016/j.phytochem.2009.06.011

Reference

4 [PMID:16418295]

Authors

Schnee C, Kollner TG, Held M, Turlings TC, Gershenzon J, Degenhardt J

Title

The products of a single maize sesquiterpene synthase form a volatile defense signal that attracts natural enemies of maize herbivores.

Journal

Proc Natl Acad Sci U S A 103:1129-34 (2006)
DOI:10.1073/pnas.0508027103

Sequence

[zma:732751]

Reference

5 [PMID:11642326]

Authors

Maruyama T, Ito M, Honda G

Title

Molecular cloning, functional expression and characterization of (E)-beta farnesene synthase from Citrus junos.

Journal

Biol Pharm Bull 24:1171-5 (2001)
DOI:10.1248/bpb.24.1171

Sequence

[ag:AAK54279]

Reference

6 [PMID:9371761]

Authors

Crock J, Wildung M, Croteau R

Title

Isolation and bacterial expression of a sesquiterpene synthase cDNA clone from peppermint (Mentha x piperita, L.) that produces the aphid alarm pheromone (E)-beta-farnesene.

Journal

Proc Natl Acad Sci U S A 94:12833-8 (1997)
DOI:10.1073/pnas.94.24.12833

Reference

7 [PMID:12481088]

Authors

Schnee C, Kollner TG, Gershenzon J, Degenhardt J

Title

The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage.

Journal

Plant Physiol 130:2049-60 (2002)
DOI:10.1104/pp.008326

Sequence

[zma:541974]

Reference

8 [PMID:15921711]

Authors

Huber DP, Philippe RN, Godard KA, Sturrock RN, Bohlmann J

Title

Characterization of four terpene synthase cDNAs from methyl jasmonate-induced Douglas-fir, Pseudotsuga menziesii.

Journal

Phytochemistry 66:1427-39 (2005)
DOI:10.1016/j.phytochem.2005.04.030