KEGG   ENZYME: 4.2.3.94
Entry
EC 4.2.3.94                 Enzyme                                 
Name
gamma-curcumene synthase;
PatTpsA (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, gamma-curcumene-forming)
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = gamma-curcumene + diphosphate [RN:R09894]
Reaction(KEGG)
R09894
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
gamma-curcumene [CPD:C20179];
diphosphate [CPD:C00013]
Comment
One of five sesquiterpenoid synthases in Pogostemon cablin (patchouli).
History
EC 4.2.3.94 created 2012
Orthology
K21933  gamma-curcumene synthase
Reference
1  [PMID:16970904]
  Authors
Deguerry F, Pastore L, Wu S, Clark A, Chappell J, Schalk M
  Title
The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases.
  Journal
Arch Biochem Biophys 454:123-36 (2006)
DOI:10.1016/j.abb.2006.08.006
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.94
IUBMB Enzyme Nomenclature: 4.2.3.94
ExPASy - ENZYME nomenclature database: 4.2.3.94
BRENDA, the Enzyme Database: 4.2.3.94

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