KEGG ENZYME: 4.2.99.20

ENZYME: 4.2.99.20

Entry

EC 4.2.99.20                Enzyme

Name

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase;
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase;
6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase;
SHCHC synthase;
MenH;
YfbB

Class

Lyases;
Carbon-oxygen lyases;
Other carbon-oxygen lyases

Sysname

5-enolpyruvoyl-6-hydroxy-2-succinylcyclohex-3-ene-1-carboxylate pyruvate-lyase [(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate-forming]

Reaction(IUBMB)

5-enolpyruvoyl-6-hydroxy-2-succinylcyclohex-3-ene-1-carboxylate = (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + pyruvate [RN:R08166]

Reaction(KEGG)

R08166

Substrate

5-enolpyruvoyl-6-hydroxy-2-succinylcyclohex-3-ene-1-carboxylate [CPD:C16519]

Product

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate [CPD:C05817];
pyruvate [CPD:C00022]

Comment

This enzyme is involved in the biosynthesis of vitamin K2 (menaquinone). In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter in the respiratory chain and is essential for their survival. It had previously been thought that the reactions carried out by this enzyme and EC 2.2.1.9, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase, were carried out by a single enzyme but this has since been disproved [2].

History

EC 4.2.99.20 created 2008 (EC 2.5.1.64 created 2003, part-incorporated 2008)

Pathway

ec00130

Ubiquinone and other terpenoid-quinone biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K08680

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase

K14759

isochorismate synthase / 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase / o-succinylbenzoate synthase

Genes

ATH:	AT1G68890(PHYLLO)

ALY:

9324753

CRB:

17894367

CSAT:

104704752 104750694 104787948

EUS:	EUTSA_v10017999mg

BRP:

103852540

BNA:

106393361

BOE:

106327192

RSZ:

108842359

THJ:

104821983

CIT:

102608540

CIC:	CICLE_v100304921m

PVY:

116119521

MINC:

123212909

TCC:

18610138

GRA:

105794273

GHI:	107887399 107936532

GAB:

108465126

HSYR:

120173346 120210713

DZI:

111318210

EGR:

104453859

GMX:

100798570

GSJ:

114387540

PVU:	PHAVU_005G022900g

VRA:

106761862

VAR:

108334153

VUN:

114181785

VUM:

124835470

CCAJ:

109807754

APRC:

113858177

MTR:

25501491

TPRA:

123924451

CAM:

101508711

PSAT:

127074909

VVO:

131642064

ADU:	107477124 127741116

AIP:

107628739

AHF:	112719735 112795954

LANG:

109332680

PCIN:

129311079

QSA:	O6P43_032844

FVE:

101297638

RCN:

112197898

PPER:

18791507

PMUM:

103342087

PAVI:

110757742

PDUL:

117614419

MDM:

103425450

MSYL:

126608834

PXB:

103946661

ZJU:

107429107

MNT:

21409174

CSAV:

115699355

CSV:

101217012

CMO:

103489211

BHJ:

120082188

MCHA:

111017565

CMAX:

111488697

CMOS:

111458428

CPEP:

111776726

RCU:

8264631

JCU:

105640708

HBR:

110660726

MESC:

110599831

POP:

7482230

PEU:

105114338

PALZ:

118047100

JRE:

108981645

CILL:

122310506

CAVE:

132177446

QSU:

112030165

QLO:

115981974

TWL:

119992272

VVI:

100241089

VRI:

117913286

SLY:

101245351

SPEN:

107017693

SOT:

102603926

SSTN:

125856412

SDUL:

129870594

CANN:

107870618

LBB:

132614793

NTA:	107794793 107804357

NSY:

104216590

NTO:

104112285

NAU:

109214856

INI:

109176245

ITR:

116001545

SIND:

105161713

OEU:

111404630

EGT:

105967597

SSPL:

121794928

SMIL:

130986282

SHIS:

125205356

APAN:

127261806

HAN:

110914946

ECAD:

122595173

LSV:

111896435

CCAV:

112523262

DCR:

108196102

CSIN:

114282620

RVL:

131302019

AEW:

130765786

BVG:

104896273

SOE:

110791623

CQI:	110686041 110721096

ATRI:

130818007

MOF:

131154364

NNU:

104597836

TSS:

122664179

PSOM:

113275718 113281895

OSA:

4329786

OBR:

102708030

OGL:

127762324

BDI:

100843372

ATS:

109752118

TDC:	119316956 119321729

TAES:

123127572 123137052 123144651

TUA:

125512485

LPER:

127326478

LRD:

124692763

SBI:

8055409

SITA:

101780975

SVS:

117859232

PVIR:

120656211 120706507

PHAI:

112893416

PDA:

103706601

EGU:

105061098

MUS:

103989974

ZOF:	122012754 122017478

DCT:

110109286

PEQ:

110018366

AOF:

109840254

MSIN:

131255652

NCOL:

116250127

ATR:

18433994

SMO:	SELMODRAFT_121498 SELMODRAFT_157803

PPP:

112287061

CRE:	CHLRE_16g659050v5

MNG:	MNEG_13906

CSL:	COCSUDRAFT_11397

CVR:	CHLNCDRAFT_137782

APRO:

F751_1303

OTA:	OT_ostta17g02170

BPG:	Bathy12g00280

MIS:	MICPUN_58883

MPP:	MICPUCDRAFT_43278(JGI:MicpuC2_43278)

CCP:	CHC_T00002409001

ECO:	b2263(menH)

ECJ:	JW2258(yfbB)

ECD:	ECDH10B_2424(yfbB)

EBW:	BWG_2037(yfbB)

ECOK:

ECMDS42_1834(yfbB)

ECOC:

C3026_12640

ECE:	Z3523(yfbB)

ECS:	ECs_3151(menH)

ECF:	ECH74115_3405

ETW:	ECSP_3141(yfbB)

ELX:	CDCO157_2915

EOI:	ECO111_3014(yfbB)

EOJ:	ECO26_3254(yfbB)

EOH:	ECO103_2730(yfbB)

ECOO:

ECRM13514_3020(yfbB)

ECOH:

ECRM13516_2965(yfbB)

ESL:

O3K_08170

ESO:

O3O_17465

ESM:

O3M_08120

ECK:	EC55989_2511(yfbB)

ECG:	E2348C_2408(yfbB)

EOK:	G2583_2804(yfbB)

ELR:	ECO55CA74_13880

ELH:

ETEC_2398

ECW:	EcE24377A_2559

EUN:	UMNK88_2816

ECP:

ECP_2307

ENA:	ECNA114_2357(yfbB)

ECOS:

EC958_2602(menH)

ECV:	APECO1_4298(yfbB)

ECOA:

APECO78_15140

ECX:	EcHS_A2409

ECM:	EcSMS35_2418

ECY:

ECSE_2523

ECR:	ECIAI1_2341(yfbB)

ECQ:	ECED1_2731(yfbB)

EUM:	ECUMN_2606(yfbB)

ECT:	ECIAI39_2411(yfbB)

EOC:	CE10_2647(menH)

EBR:	ECB_02190(yfbB)

ECOB:

C3029_15505

EBL:	ECD_02190(menH)

EBE:	B21_02149(menH)

EBD:

ECBD_1395

ECI:	UTI89_C2547(yfbB)

EIH:	ECOK1_2500(menH)

ECZ:	ECS88_2414(yfbB)

ECC:	c2807(yfbB)

ELO:	EC042_2507

ELN:	NRG857_11480

ESE:

ECSF_2144

ECL:	EcolC_1385

EKO:	EKO11_1500

EKF:	KO11_11365(yfbB)

EAB:	ECABU_c25990(yfbB)

EDH:	EcDH1_1394

EDJ:	ECDH1ME8569_2200(yfbB)

ELU:	UM146_05480

ELW:	ECW_m2455(yfbB)

ELL:	WFL_12015(yfbB)

ELC:	i14_2606(yfbB)

ELD:	i02_2606(yfbB)

ELP:	P12B_c2358(yfbB)

ELF:	LF82_3047(yfbB)

ECOL:

LY180_11755

ECOI:

ECOPMV1_02425(menH)

ECOJ:

P423_12670

EFE:	EFER_0905(yfbB)

EAL:	EAKF1_ch3715

EMA:	C1192_00565

ESZ:	FEM44_01515(menH)

ERUY:

OSH18_19995(menH)

STY:	STY2538(yfbB)

STT:	t0555(yfbB)

SEX:	STBHUCCB_5960

SENT:

TY21A_02825

STM:	STM2308(yfbB)

SEO:	STM14_2846(yfbB)

SEV:	STMMW_23321

SEY:	SL1344_2277(yfbB)

SEM:	STMDT12_C23290

SEJ:	STMUK_2338(yfbB)

SEB:	STM474_2404(yfbB)

SEF:	UMN798_2490

SETU:

STU288_07915

SETC:

CFSAN001921_05255

SENR:

STMDT2_22771(yfbB)

SEND:

DT104_23661(yfbB)

SENI:

CY43_12365

SEEN:

SE451236_17735

SPT:	SPA0555(yfbB)

SEK:

SSPA0519

SPQ:	SPAB_00673

SEI:	SPC_1403(yfbB)

SEC:	SCH_2308(yfbB)

SEH:	SeHA_C2548

SHB:

SU5_02903

SENH:

CFSAN002069_20305

SEEH:

SEEH1578_20815

SEE:	SNSL254_A2493

SENN:

SN31241_34130

SEW:	SeSA_A2536

SEA:	SeAg_B2444

SENS:

Q786_11380

SED:

SeD_A2652

SEG:	SG2337(yfbB)

SEL:

SPUL_0582

SEGA:

SPUCDC_0582

SET:	SEN2290(yfbB)

SENA:

AU38_11575

SENO:

AU37_11585

SENV:

AU39_11585

SENQ:

AU40_12965

SENL:

IY59_11900

SENJ:

CFSAN001992_22035

SEEC:

CFSAN002050_18465

SEEB:

SEEB0189_008030

SEEP:

I137_02685

SENB:

BN855_23890

SENE:

IA1_11495

SENC:

SEET0819_18630

SES:	SARI_00591

SBG:	SBG_2096(yfbB)

SBZ:

A464_2422

SALZ:

EOS98_07505

SFL:	SF2342(yfbB)

SFX:	S2476(yfbB)

SFV:	SFV_2334(yfbB)

SFE:	SFxv_2586(yfbB)

SFN:

SFy_3332

SFS:

SFyv_3407

SFT:	NCTC1_02576(menH)

SSN:	SSON_2324(yfbB)

SBO:	SBO_2300(yfbB)

SBC:	SbBS512_E2642

SDY:	SDY_2459(yfbB)

SDZ:	Asd1617_03318

SHQ:	A0259_15140

ENC:	ECL_03613(menH)

ENL:	A3UG_15950

ECLG:

EC036_31000

ECLE:

ECNIH2_15915

ECLN:

ECNIH4_07265

ECLI:

ECNIH5_14860

ECLX:

LI66_15260

ECLY:

LI62_16760

ECLZ:

LI64_14695

EHM:	AB284_10160

EXF:	BFV63_15080

ECLA:

ECNIH3_14955

ECLC:

ECR091_14890

EAU:	DI57_03825

EKB:	BFV64_15595

ENO:	ECENHK_15385

EEC:	EcWSU1_03141(menH)

ELG:	BH714_11755

ECAN:

CWI88_06870

ERN:	BFV67_15250

ECLS:

LI67_016505

ECHG:

FY206_17065(menH)

ESH:	C1N69_15760

EPT:	HWQ17_20485(menH)

ENT:	Ent638_2813

EAS:	Entas_2985

ENR:	H650_07215

ENX:	NI40_015490

ENF:	AKI40_1592

LNI:	CWR52_19640

EBG:	FAI37_13715(menH)

END:	A4308_20055

ENZ:	G0034_16000(menH)

ENS:	HWQ15_00770(menH)

ENK:	LOC22_03385(menH)

EHU:	D5067_0007370(menH)

EMOR:

L6Y89_15080(menH)

ENB:	ELK40_15775

EQU:	OM418_15240(menH)

EPU:	QVH39_16040(menH)

ESA:

ESA_00950

CSK:	ES15_1204(menH)

CSZ:	CSSP291_04805

CSJ:	CSK29544_02257

CCON:

AFK62_13335

CDM:	AFK67_14120

CSI:	P262_01845

CMJ:	AFK66_006145

CUI:	AFK65_13615

CMW:	AFK63_04700

CTU:	CTU_28950(menH)

KPN:	KPN_02661(yfbB)

KPU:	KP1_3902(yfbB)

KPM:	KPHS_37280

KPP:

A79E_1441

KPH:	KPNIH24_10015

KPZ:	KPNIH27_17815

KPV:	KPNIH29_18610

KPW:	KPNIH30_18830

KPY:	KPNIH31_17760

KPG:	KPNIH32_19160

KPC:	KPNIH10_18195

KPQ:	KPR0928_18215

KPT:	VK055_4854(menH)

KPO:	KPN2242_16405

KPR:	KPR_2046(menH)

KPI:	D364_13560

KPA:	KPNJ1_01684

KPS:	KPNJ2_01652

KPX:	PMK1_00159(menH)

KPB:	FH42_09425

KPNE:

KU54_007765

KPNU:

LI86_07770

KPNK:

BN49_3878(menH)

KVA:

Kvar_1392

KPE:

KPK_1488

KPK:	A593_03170

KVD:	KR75_00830

KVQ:	SP68_07360

KOX:

KOX_26275

KOE:

A225_4155

KOY:	J415_11350

KOM:	HR38_24405

KMI:	VW41_15530

KOK:	KONIH1_20485

KOC:	AB185_15840

KQU:	AVR78_22600

EAE:

EAE_24335

EAR:

CCG28951

KQV:	B8P98_08475

KLL:	BJF97_20450

KLW:	DA718_08560

KAR:	LGL98_07475(menH)

KGR:	JJJ10_08270(menH)

KPAS:

LUW96_26910(menH)

KLC:	K7H21_08280(menH)

KLM:	BWI76_20070

REE:	electrica_01486(menH)

ROR:	RORB6_01210

RON:	TE10_20175

RPLN:

B1209_07390

RAO:	DSD31_07590

RTG:	NCTC13098_02011(menH)

CRO:

ROD_26701

CKO:

CKO_00527

CFD:	CFNIH1_22885

CBRA:

A6J81_24880

CWE:	CO701_06575

CYO:	CD187_07820

CPOT:

FOB25_18945(menH)

CFQ:	C2U38_16840

CSED:

JY391_07515(menH)

CAMA:

F384_12120

CAF:	AL524_10775

CIF:	AL515_15790

CFAR:

CI104_17455

CIR:	C2U53_27305

CIE:	AN232_12475

CPAR:

CUC49_11840

CTEL:

GBC03_13010(menH)

CITZ:

E4Z61_01415(menH)

CARS:

E1B03_18275(menH)

CIX:	M4I31_07685(menH)

CIB:	HF677_007785(menH)

CENS:

P2W74_07470(menH)

EBT:	EBL_c12860(yfbB)

CNT:	JT31_19565

CEM:	LH23_21515

CEN:	LH86_20105

CLAP:

NCTC11466_01326(menH)

PGE:	LG71_12060

ESC:	Entcl_1460

KLE:	AO703_14565

KSA:	C813_23220

KOR:	AWR26_08170(menH)

KRD:	A3780_15815

KCO:	BWI95_20940

KOT:	EH164_07230

KPSE:

IP581_15515(menH)

KOB:	HF650_16090(menH)

KOO:	O9K67_07875(menH)

KIE:	NCTC12125_00420(menH)

KAS:	KATP_14150(menH)

KLU:	K7B04_21870(menH)

KCY:	RIN60_07390(menH)

LAX:	APT61_06925

LEI:	C2U54_20705

LEH:	C3F35_19065

LEE:	DVA44_07060

LER:	GNG29_15710(menH)

LEA:	GNG26_15560(menH)

LPNU:

KQ929_06110(menH)

LEY:	DVA43_01795

LAZ:	A8A57_14635

LEF:	LJPFL01_2884

LEW:	DAI21_12010

BUF:	D8682_08920

BAGE:

BADSM9389_29170

BFT:	MNO13_17640(menH)

SYM:	K6K13_05865(menH)

AHN:	NCTC12129_01547(yfbB)

ASUB:

NLZ15_15270(menH)

YRE:	HEC60_10695(menH)

SGOE:

A8O29_007165(menH)

KIN:	AB182_07030

PDZ:	HHA33_10105(menH)

METY:

MRY16398_16350(menH)

IZH:	FEM41_22230(menH)

PSHI:

SAMEA2665130_2006(menH)

PSGC:

G163CM_03900(menH_3)

SCOL:

KFZ77_13485(menH)

PVJ:	LMA04_19085(menH)

SUPE:

P0H77_14725(menH)

TOE:	QMG90_07705(menH)

EBF:

D782_1401

EBC:	C2U52_17565

EBU:	CUC76_23075

EBB:

F652_1867

YPE:

YPO2526

YPK:

y1661

YPH:	YPC_1595(yfbB)

YPA:

YPA_2018

YPN:

YPN_2121

YPM:	YP_2337(mhpC3)

YPP:	YPDSF_1936

YPG:	YpAngola_A1784

YPZ:

YPZ3_2232

YPT:	A1122_13495

YPD:

YPD4_2483

YPX:

YPD8_2178

YPW:	CH59_62(menH)

YPJ:	CH55_84(menH)

YPV:	BZ15_1009(menH)

YPL:	CH46_2587(menH)

YPS:

YPTB2559

YPO:	BZ17_4079(menH)

YPI:	YpsIP31758_1483

YPY:

YPK_1590

YPB:

YPTS_2653

YPQ:	DJ40_3984(menH)

YPU:	BZ21_1855(menH)

YPR:	BZ20_3650(menH)

YPC:	BZ23_2139(menH)

YPF:	BZ19_1921(menH)

YEN:

YE1376

YEP:	YE105_C2740

YEY:

Y11_02451

YEL:	LC20_03663

YEW:	CH47_795(menH)

YET:	CH48_282(menH)

YEF:	FORC2_1418

YEE:	YE5303_11601

YSI:	BF17_22270

YAL:	AT01_1164(menH)

YFR:	AW19_1834(menH)

YIN:	CH53_356(menH)

YKR:	CH54_3952(menH)

YRO:	CH64_1176(menH)

YRU:	BD65_830(menH)

YRB:	UGYR_04715

YAK:	ACZ76_15640

YMA:	DA391_15190

YHI:	D5F51_05350

YCA:	F0T03_07790(menH)

YMO:	HRD69_11990(menH)

YAS:	N0H69_10380(menH)

YKI:	HRD70_11770(menH)

YEG:	PL78_16815

SMAR:

SM39_2880

SMAC:

SMDB11_2679

SMW:	SMWW4_v1c33920(menH)

SPE:

Spro_3282

SRR:	SerAS9_3478

SRL:	SOD_c31980(menH)

SRY:	M621_17410

SPLY:

Q5A_017360(menH)

SRS:	SerAS12_3479

SRA:	SerAS13_3480

SMAF:

D781_3075

SLQ:	M495_16855

SERF:

L085_11725

SERS:

SERRSCBI_16460

SFW:	WN53_25535

SFG:	AV650_21205

SRZ:	AXX16_1999

SERM:

CLM71_16265

SQU:	E4343_24355(menH)

SFJ:	SAMEA4384070_3398(menH)

SOF:	NCTC11214_03404(menH)

SSUR:

ATE40_013605

SURI:

J0X03_07070(menH)

SRHZ:

FO014_17965(menH)

SENP:

KHA73_16540(menH)

SNEM:

NLX84_17015(menH)

SNEV:

OI978_15475(menH)

SFO:	Z042_03230

RAH:	Rahaq_1278

RACE:

JHW33_00900(menH)

RAQ:	Rahaq2_1351

RAA:

Q7S_06140

ROX:	BV494_01700

RVC:	J9880_14210(menH)

RBON:

QNM34_06545(menH)

RIU:	I2123_08405(menH)

GQU:	AWC35_19835

EAME:

GXP68_06775(menH)

CARU:

P0E69_06110(menH)

NIG:	C1N62_05125

PROD:

PCO85_06770(menH)

SERA:

Ser39006_018675

SERQ:

CWC46_18675

ECA:

ECA1212

PATR:

EV46_06095

PATO:

GZ59_12410

PCT:

PC1_1112

PCC:	PCC21_011430

PCV:	BCS7_05765

PWA:	Pecwa_3202

PEC:

W5S_3200

PWS:	A7983_14700

PPOA:

BJK05_00800

PBRA:

B5S52_15960

PPUJ:

E2566_06245(menH)

PARI:

I2D83_16425(menH)

PAQU:

DMB82_0014820(menH)

PVZ:	OA04_12680(menH)

PPAV:

LOZ86_15265(menH)

PQU:	IG609_014560(menH)

PPOO:

LW347_06185(menH)

PCAC:

OI450_04880(menH)

PACB:

M9782_08120(menH)

DDD:	Dda3937_01782(yfbB)

DZE:	Dd1591_3013

DDC:	Dd586_1087

DZC:	W909_05480

DSO:	A4U42_14820

CED:	LH89_06405

DFN:	CVE23_06300

DDQ:

DDI_0952

DAQ:	DAQ1742_03104(menH)

DIC:	Dpoa569_002644(menH)

DLC:	O1Q98_17450(menH)

DDA:	Dd703_1046

BRB:	EH207_05040

BNG:	EH206_16150

BIZ:	HC231_17055(menH)

LBQ:	CKQ53_10020

LPOP:

I6N93_05035(menH)

SOD:	Sant_1358(menD)

EBI:	EbC_30510(menH)

EPE:	CI789_03390

ERWI:

GN242_06460(menH)

ETP:	LU633_17240(menH)

ERP:	LJN55_15865(menH)

PANP:

PSNIH2_04385

PALH:

B1H58_13755

PGZ:	C2E15_14365

PCD:	C2E16_14430

MINT:

C7M51_02078(menH)

MTHI:

C7M52_00764(menH_1)

MHAN:

K6958_13885(menH)

PLU:

plu3072

PLUM:

A4R40_15355

PAY:

PAU_01539

PTT:	VY86_16300

PAKH:

B0X70_15745

PLUI:

CE143_15740

PMR:	PMI1744(yfbB)

PMIB:

BB2000_1852(yfbB)

PVL:	AOB99_10710

PVG:	CRN77_10180

PHAU:

PH4a_00435

PROT:

BTA34_10380

PCOL:

F1325_12325(menH)

PCIB:

F9282_12400(menH)

PPEE:

I6G31_16140(menH)

XBO:	XBJ1_0739(yfbB)

XBV:	XBW1_2774(menH)

XNE:	XNC1_2846(yfbB)

XNM:	XNC2_2741(yfbB)

XDO:	XDD1_2569(menH)

XPO:	XPG1_1254(menH)

XHO:	A9255_08420

XBU:	HGO23_07885(menH)

XGR:	QL128_07335(menH)

PSI:

S70_02315

PSX:	DR96_3623(menH)

PSTA:

BGK56_05645

PTHA:

OI982_21060(menH)

PRG:	RB151_026550(menH)

PALA:

CO695_11860

PHEI:

NCTC12003_01572(menH)

PRQ:	CYG50_02785(menH)

PRJ:	NCTC6933_02322(menH)

PVC:	G3341_08190(menH)

PMAG:

JI723_08140(menH)

PHAG:

PZ638_08265(menH)

MMK:

MU9_2541

ANS:	ArsFIN_26280(menH)

AET:	LDL57_05425(menH)

AAPC:

QG404_06720(menH)

MWI:	MNY66_09780(menH)

EIC:	NT01EI_2649

ETR:	ETAE_2357(yfbB)

ETD:

ETAF_2129

ETE:	ETEE_0380(menH)

ETC:	ETAC_11130

EDW:	QY76_08570

EHO:	A9798_05390

HAV:	AT03_14515

HPAR:

AL518_11700

OPO:	DSM2777_17885

LPV:	HYN51_15525

PRAG:

EKN56_05660

PFQ:	QQ39_12005

LRI:	NCTC12151_01276(menH)

HIN:

HI_0282

HIT:

NTHI0391

HIP:	CGSHiEE_01645

HIQ:	CGSHiGG_04205

HIF:	HIBPF_02250

HIL:	HICON_11920

HIU:

HIB_04000

HIE:	R2846_0298(menH)

HIZ:	R2866_0297(menH)

HIK:	HifGL_001790(menH)

HIA:

H733_0178

HIH:	NF38_03970

HIW:	NTHI477_01327(menH)

HIC:	NTHIC486_00706(menH)

HIX:	NTHI723_01411(menH)

HPR:	PARA_00880

HDU:

HD_1854

HAY:	C3V42_07015

HPIT:

NCTC13334_01273(menH)

HHZ:	NCTC10839_00884(menH)

HAEG:

NCTC8502_00939(menH)

HPAA:

E5Q53_07435(menH)

HSEM:

L3077_04815(menH)

HAP:	HAPS_1251(yfbB)

HPAZ:

K756_00420

HPAS:

JL26_11125

HPAK:

JT17_09350

GLE:	CJD39_10740

HSO:

HS_0616

HSM:

HSM_0967

PMU:

PM0055

PMV:	PMCN06_1253(menH)

PUL:	NT08PM_1337

PMP:

Pmu_12670

PMUL:

DR93_2023(menH)

PDAG:

4362423_00351(menH)

PSKY:

A6B44_10680

PATL:

KGI96_09140(menH)

PCAI:

K7G93_000109(menH)

MSU:	MS1793(mhpC)

BSUN:

A4G13_06635

MHT:

D648_2920

MHQ:	D650_25220

MHAT:

B824_23770

MHX:	MHH_c08350(menH)

MHAE:

F382_09335

MHAO:

J451_09555

MHAL:

N220_01415

MHAQ:

WC39_12420

MHAY:

VK67_12425

MVR:	X781_22190

MVI:

X808_1910

MVG:

X874_1990

MVE:	X875_18940

MGRA:

A4G16_09005

MBOS:

ICJ55_02930(menH)

MPEG:

HV560_01595(menH)

MANN:

GM695_01520(menH)

APL:

APL_1749

APJ:

APJL_1784

APA:

APP7_1834

ASU:

Asuc_0652

ASI:	ASU2_09815

ASS:	ASU1_09860

AEU:	ACEE_09300

APOR:

DDU33_00885

AIO:	EXH44_07065(menH)

ADP:	NCTC12871_00402(menH)

ALIG:

NCTC10568_02125(menH)

AART:

NYR89_08565(menH)

AGP:	NYR63_09615(menH)

AGK:	NYR60_07080(menH)

AAP:	NT05HA_2368

AAZ:	ADJ80_04500

AAT:

D11S_2020

AAO:	ANH9381_0205

AAN:

D7S_01921

AAH:	CF65_00087

AACN:

AANUM_0039

AACT:

ACT75_03275

ASEG:

NCTC10977_00866(menH)

AGJ:	J5A60_01965(menH)

GAN:	UMN179_00770

GSS:	NYR30_09995(menH)

BTO:

WQG_21340

BTRE:

F542_1250

BTRH:

F543_1290

BTRA:

F544_21890

APAG:

EIA51_03785

AVT:	NCTC3438_01960(menH)

RPNE:

NCTC8284_01143(menH)

RHEY:

FEE42_11115(menH)

RHAE:

IHV77_03460(menH)

OOI:	A6A10_08110

FCL:	A4G17_03480

BHUD:

A6A11_08720

MSEP:

CEP49_06850

PAET:

NCTC13378_01484(menH)

VCH:

VC_1974

VCF:	IR04_15015

VCS:

MS6_1731

VCE:	Vch1786_I1466

VCQ:	EN18_12975

VCJ:	VCD_002393

VCI:

O3Y_09535

VCO:	VC0395_A1560

VCR:	VC395_2089

VCM:	VCM66_1898

VCL:	VCLMA_A1715

VCX:	VAA049_905(menH)

VCZ:	VAB027_2610(menH)

VVU:

VV1_3171

VVY:

VV1117

VVM:	VVMO6_02110

VVL:	VV93_v1c10380(menH)

VPA:

VP0930

VPB:

VPBB_0888

VPK:	M636_17025

VPF:	M634_06660

VPH:	VPUCM_1031

VHA:	VIBHAR_01430

VCA:	M892_05895

VAG:

N646_0004

VEX:	VEA_004031

VDB:	AL552_13040

VHR:	AL538_14315

VNA:	PN96_08905

VOW:	A9237_03700

VRO:	BSZ04_18575

VSP:

VS_2190

VEJ:	VEJY3_04270

VFU:	vfu_A01340

VNI:	VIBNI_A2413(menH)

VAN:

VAA_03316

LAG:	N175_06010

VAU:	VANGNB10_cI1810c(ytxM_menH?)

VCY:	IX92_04415

VCT:	JV59_10105

VTU:	IX91_10005

VEU:	IXK98_18805(menH)

VSI:	MTO69_04790(menH)

VFL:	AL536_10665

VMI:	AL543_19140

VBR:	A6E01_03735

VSC:	VSVS12_01286(menH)

VGA:	BSQ33_03385

VSH:	BSZ05_11090

VQI:	CCZ37_08595

VTA:	A1984(yfbB)

VAF:	D1115_10620

VNL:	D3H41_04740

VCC:	FAZ90_10485(menH)

VAS:	GT360_04885(menH)

VAQ:	FIV01_09670(menH)

VSR:	Vspart_01145(menH)

VKA:	BTD91_11005(menH)

VZI:	G5S32_09705(menH)

VNV:	IF132_10670(menH)

VGI:	MID13_04450(menH)

VSL:	LTQ54_04275(menH)

VPL:	SA104470976_01679(menH)

VJP:	NP165_04765(menH)

VPG:	LZI70_02475(menH)

VOS:	KNV97_08220(menH)

VTI:	CEQ48_09110

VCRA:

IS519_05750(menH)

VNP:	KW548_13400(menH)

VLE:	ISX51_11575(menH)

VSY:	K08M4_20750(menH)

VRU:	RND59_00415(menH)

VMT:	QYQ96_04570(menH)

VFI:	VF_1670(yfbB)

VFM:	VFMJ11_1795

VSA:	VSAL_I1100

AWD:	AWOD_I_1789

PPR:	PBPRA2623(STM2308)

PGB:	H744_2c2764

PDS:	CAY62_09600

PGH:	FH974_11075(menH)

GHO:	AL542_04710

GKD:	K6Q96_04710(menH)

SALY:

E8E00_03470(menH)

SKS:	FCN78_09375(menH)

SCOT:

HBA18_09860(menH)

SPRO:

N7E60_10360(menH)

SON:	SO_4574(menH)

SFR:

Sfri_0281

SAZ:

Sama_3461

SBL:

Sbal_0177

SBM:	Shew185_4158

SBN:	Sbal195_4289

SBP:	Sbal223_0178

SBT:	Sbal678_4322

SBS:	Sbal117_0276

SBB:	Sbal175_4069

SLO:

Shew_3600

SPC:	Sputcn32_0309

SHP:	Sput200_4070

SSE:

Ssed_0225

SPL:

Spea_3972

SHE:	Shewmr4_3768

SHM:	Shewmr7_3841

SHN:	Shewana3_3966

SHW:	Sputw3181_3899

SHL:

Shal_0296

SWD:

Swoo_0208

SWP:

swp_4793

SVO:

SVI_0219

SHF:	CEQ32_15025(menH)

SJA:	SJ2017_0217

SPSW:

Sps_00298

SBJ:	CF168_19985(menH)

SMAV:

CFF01_17870(menH)

SHEW:

CKQ84_06560(menH)

SALG:

BS332_08570

SLJ:	EGC82_21075(menH)

SMAI:

EXU30_08530(menH)

SPOL:

FH971_01295(menH)

SBK:	SHEWBE_0798(menH)

SKH:	STH12_03402(menH)

SAES:

HBH39_16495(menH)

SLIT:

JQC75_17800(menH)

SDK:	KHX94_09855(menH)

SCAA:

TUM17387_36810(menH)

SPSH:

FM037_01230(menH)

SEUR:

FM038_001250(menH)

SYK:	KDN34_16590(menH)

SCYP:

JYB88_17485(menH)

SAVI:

JYB87_00890(menH)

SSEM:

JYB85_18040(menH)

SGLA:

FJ709_01110(menH)

SINV:

K8B83_00485(menH)

SXM:	MKD32_19645(menH)

SVM:	KDH10_002747(menH)

SHEJ:

MZ182_19500(menH)

SCHK:

GII14_00700(menH)

SACH:

K0H61_16620(menH)

SAEG:

K0H80_18450(menH)

SDEO:

D0436_20800(menH)

SMES:

K0I73_17745(menH)

SHAO:

K0H81_18940(menH)

SZH:	K0H63_18910(menH)

SSPA:

K0I31_18705(menH)

SHNS:

K0J45_18475(menH)

SRHS:

K0I63_18665(menH)

SPSJ:

K0I62_17955(menH)

SMAY:

K0H60_19810(menH)

SOG:	RA178_21140(menH)

SPSR:

EGC80_03115(menH)

AGZ:	M0C34_19570(menH)

PIN:

Ping_0351

PSY:	PCNPT3_11350

FBL:

Fbal_0043

FES:	HER31_15500(menH)

MVS:	MVIS_2785(menH)

MYA:	MORIYA_1408(menH)

MMAA:

FR932_09760(menH)

MOQ:	HWV03_07785(menH)

TTU:	TERTU_2727

ALV:	Alvin_0765

ATEP:

Atep_04790

TVI:	Thivi_4014

TMB:	Thimo_0879

MPUR:

MARPU_04580

TTP:	E6P07_11725

THIP:

N838_08245

THIM:

KFB96_25285

TBOG:

LT988_02490

TLR:	Thiosp_01787(menH)

TFRI:

Thiofri_02992(menH)

TWG:	Thiowin_02885(menH)

HHA:

Hhal_1128

HHK:	HH1059_00680(menH)

HHC:	M911_03115

EBS:	ECTOBSL9_1653

TNI:	TVNIR_1662(menH_[H])

TTI:	THITH_08380

HAK:	KO116_00675

HAM:

HALO0681

HHH:	CLM76_07755(menH)

HAXI:

HAALTHF_15410n

HPRO:

LMS44_19985(menH)

HALF:

QEN58_17285(menH)

HASO:

B2G49_15220

HALW:

B6N23_03675(menH)

HOL:	HORIV_62680(menH)

HSR:	HSBAA_59590(menH)

HPIZ:

GYM47_15755(menH)

HNP:	SR894_18345(menH)

GSN:	YC6258_05119

RFO:	REIFOR_00521(menH)

ENW:	MJO57_20150(menH)

ENG:	O2T12_16630(menH)

EMP:	EZMO1_3281(menH)

AHA:

AHA_0530

AHY:	AHML_02715

AHD:	AI20_16740

AHR:	V428_02860

AHP:	V429_02860

AHJ:	V469_20460

AHH:	RY45_03090

AHI:	VU14_19845

AAJ:	BOQ57_02560

ASA:

ASA_3736

AEO:	O23A_p4193

AVR:

B565_0485

AVO:	AMS64_03880

AMED:

B224_4844

ASR:	WL1483_3250(menH)

ADH:	CK627_06440

ACAV:

VI35_18870(menH)

AEM:	CK911_14180

AEA:	C2U39_01750(menH)

ARV:	C7N77_02050(menH)

AES:	C2U30_11745(menH)

AEL:	NCTC12917_00432(menH)

ASIM:

FE240_15845(menH)

AALL:

I6G90_13305(menH)

AJD:	I6H43_13385(menH)

ARIV:

KYK33_01680(menH)

ASAA:

KXJ75_02325(menH)

AEJ:	E5E97_06920(menH)

ABES:

IU367_02295(menH)

TAU:

Tola_0432

CDIZ:

CEDIAZO_00455(menH_1)

RGE:	RGE_06710(menH)

RBN:	RBXJA2T_16477

ASAL:

CFBP5507_17905

BVR:

BVIR_916

BLAG:

BLTE_27380(menH)

SDO:	SD1155_07510(menH)

GFU:	KM031_17780

DAL:

Dalk_1410

SAT:

SYN_02621

MXA:

MXAN_3529

MSD:	MYSTI_04445

MYM:	A176_003382

MFB:	MFUL124B02_23770

CCX:	COCOR_04514(ytxM)

MFU:	LILAB_25615

MMAS:

MYMAC_003470

SUR:	STAUR_4046

AGE:	AA314_05027

AVM:	JQX13_39360(menH)

MBD:	MEBOL_006859

CFUS:

CYFUS_004548

CCRO:

CMC5_010840

SAMY:

DB32_008588

HOH:

Hoch_5610

BSED:

DN745_05875

PCAY:

FRD00_22870

BBA:

Bd3483

BBAT:

Bdt_3391

BBW:

BDW_12895

BBAC:

EP01_02580

BDQ:	CIK05_02230

BDC:	DOE51_17070

BDZ:	DOM22_17965

BDK:	HW988_17080

BEX:

A11Q_485

PSTI:

SOO65_13785

SBF:	JCM31447_318500

PIJ:	QEJ31_02635

SAQI:

AXG55_00745

BSU:	BSU30810(ytxM)

BSR:

I33_3140

BSL:

A7A1_2153

BSH:	BSU6051_30810(ytxM)

BSY:	I653_14770

BSUT:

BSUB_03271(ytxM)

BSUL:

BSUA_03271(ytxM)

BSUS:

Q433_16715

BSO:	BSNT_09504(ytxM)

BSN:	BSn5_06250

BSQ:	B657_30810(ytxM)

BSX:	C663_2930(ytxM)

BSP:	U712_15305

BSS:	BSUW23_14955(ytxM)

BST:

GYO_3335

BIT:	BIS30_04795

BLI:	BL02407(ytxM)

BLD:	BLi03221(ytxM)

BLH:	BaLi_c32950(menH2)

BAY:	RBAM_027790(menH)

BAQ:	BACAU_2791(ytxM)

BYA:	BANAU_2993(ytxM)

BAMP:

B938_14335

BQY:	MUS_3368(ytxM)

BAML:

BAM5036_2713(menH)

BAMA:

RBAU_2913(menH)

BAMN:

BASU_2719(menH)

BAMB:

BAPNAU_2946(ytxM)

BAMT:

AJ82_15745

BAMY:

V529_30590(ytxM)

BMP:	NG74_02922(menH)

BAO:	BAMF_2861(ytxM)

BAZ:	BAMTA208_15080(ytxM)

BQL:	LL3_03157(ytxM)

BXH:	BAXH7_03090(ytxM)

BAMI:

KSO_005175

BAMC:

U471_29010

BAMF:

U722_14995

BSIA:

CWD84_05485(menH)

BAE:	BATR1942_13215

BVM:	B9C48_14195

BSON:

S101395_01270(menH)

BHT:	DIC78_16195(menH)

BMOJ:

HC660_29450(menH)

BTEQ:

G4P54_15600(menH)

BIQ:	AN935_15430

BSTR:

QI003_18615(menH)

BAN:	BA_5110(menH)

BAR:

GBAA_5110

BAT:

BAS4749

BAH:	BAMEG_5144

BAI:

BAA_5122

BAX:	H9401_4880

BANT:

A16_59530

BANR:

A16R_51690

BANS:

BAPAT_4902

BANH:

HYU01_24875

BANV:

DJ46_3767(menH)

BCE:

BC4854

BCA:

BCE_5014

BCZ:	BCE33L4609

BCR:	BCAH187_A4996

BCB:	BCB4264_A4985(menH)

BCU:	BCAH820_4967

BCG:	BCG9842_B0253

BCQ:

BCQ_4672

BCX:

BCA_4990

BAL:	BACI_c48600

BNC:

BCN_4772

BCF:

bcf_24340

BCER:

BCK_10865

BCY:	Bcer98_3492

BTK:	BT9727_4587

BTL:

BALH_4420

BTB:	BMB171_C4493

BTT:

HD73_5171

BTHR:

YBT1520_25625

BTHI:

BTK_25500

BTC:	CT43_CH4879

BTF:	YBT020_23950

BTG:	BTB_c50150(ytxM)

BTI:

BTG_24525

BTN:	BTF1_22900

BTHT:

H175_ch4962

BTHU:

YBT1518_26875

BTW:	BF38_610(menH)

BTHY:

AQ980_05540

BWE:	BcerKBAB4_4696

BWW:	bwei_0027(menH)

BMYO:

BG05_1169(menH)

BTY:	Btoyo_2097

BMYC:

DJ92_1939(menH)

BBY:	CY96_23435

BWD:	CT694_25970(menH)

BTRO:

FJR70_18245(menH)

BMOB:

MLA2C4_25265(menH)

BNT:	GSN03_23170(menH)

BPAC:

LMD38_02580(menH)

BPAN:

NLJ82_23845(menH)

BALU:

QRY64_27205(menH)

BPU:

BPUM_2717

BPUM:

BW16_14650

BPUS:

UP12_13905

BIF:	N288_20410

BMET:

BMMGA3_13695(ytxM)

BSM:	BSM4216_2992

BGY:

BGLY_3638

BWH:	A9C19_04000

BXI:	BK049_13445

BALT:

CFN77_14595(menH)

BAER:

BAE_02120(menH)

BSAF:

BSL056_15300

BFD:	NCTC4823_01167(menH)

BBAD:

K7T73_15180(menH)

BCAB:

EFK13_15660(menH)

BRY:	M0696_15370(menH)

BJS:

MY9_3085

BACI:

B1NLA3E_17845

GST:	HW35_06390

BACW:

QR42_13725

BACP:

SB24_14845

BACB:

OY17_17210

BACO:

OXB_0011

BACY:

QF06_13590

BACL:

BS34A_33470(ytxM)

BALM:

BsLM_3067

BACS:

AUL54_15840

BACQ:

DOE78_19600(menH)

BACA:

FAY30_18955(menH)

BAQU:

K6959_13425(menH)

BZH:	NF868_12775(menH)

BHAI:

KJK41_17435(menH)

BCAO:

LC087_09475(menH)

BARD:

QRY57_23865(menH)

BAEI:

RE735_05805(menH)

BHK:	B4U37_17570

BCOH:

BC6307_17615

BCIR:

C2I06_12015(menH)

NTX:	NQZ71_06490(menH)

BMQ:

BMQ_4890

BMD:

BMD_4876

BMH:	BMWSH_0356

BMEG:

BG04_1879(menH)

BEO:

BEH_21860

BFX:	BC359_03290

PKS:	IE339_21050(menH)

BGI:	BGM20_09360

BON:	A361_22875

BKO:	CKF48_15555(menH)

CGOT:

J1899_17650(menH)

CSUA:

IM538_19590(menH)

CFIR:

NAF01_20620(menH)

CSPG:

LS684_16885(menH)

CPSS:

M5V91_26470(menH)

BDA:	FSZ17_18290(menH)

OIH:

OB2324

OCN:	CUC15_13250(menH)

OJD:	NP439_17915(menH)

OON:	NP440_16645(menH)

GKA:

GK2874

GTE:	GTCCBUS3UF5_32330

GTK:	GT3570_14055

GTM:	GT3921_05040

GLI:	GLN3_07120

BCAL:

CWI35_13860(menH)

GTN:

GTNG_2772

GWC:	GWCH70_2798

GYC:	GYMC61_0569

GYA:	GYMC52_2986

GCT:	GC56T3_0613

GMC:	GY4MC1_0721

GGH:	GHH_c29490(ytxM)

GJF:	M493_14890

GEA:	GARCT_02903

GEL:	IB49_06255

GSE:	GT50_05950

GSR:	GS3922_01885

GEJ:	A0V43_12270

GZA:	IC807_10525(menH)

GTH:	Geoth_0720

PTL:	AOT13_18670

PTB:	DER53_01790(menH)

PCAL:

BV455_02463(menH)

PARG:

PspKH34_06270(menH)

AFL:

Aflv_0382

AGN:	AFK25_12270

ANM:	GFC28_3292(menH)

AAMY:

GFC30_3233(menH)

ANL:	GFC29_2142(menH)

AND:	GRQ40_15145(menH)

ACAI:

ISX45_12660(menH)

LSP:

Bsph_4276

LGY:	T479_18060

LFU:	HR49_05780

LYS:	LBYS11_17590(menH)

LYB:	C3943_20600(menH)

LYZ:	DCE79_13825(menH)

LYG:	C1N55_14560(menH)

LPAK:

GDS87_18590(menH)

LAGR:

FJQ98_22275(menH)

LMAC:

I6G82_01805(menH)

LYC:	FH508_0018605(menH)

LCAP:

ICJ70_06405(menH)

LYP:	MTP04_28210(menH)

LIU:	OU989_17015(menH)

LLB:	R6U77_11460(menH)

HHD:	HBHAL_3862(menH)

HMN:	HM131_07660

HLI:	HLI_17485(menH)

HNZ:	P9989_14375(menH)

HSAN:

MUN89_09265(menH)

HSHI:

MUO14_04370

HAMY:

MUO15_20230(menH)

TAID:

KS242_12180(menH)

VIR:	X953_13270

VHL:	BME96_12150

VIG:	BKP57_03020

VIL:	CFK37_12410(menH)

VNE:	CFK40_07730(menH)

VPN:	A21D_02870(menH)

VIM:	GWK91_09140(menH)

VPT:	KBP50_05740(menH)

VNT:	OLD84_12400(menH)

VIK:	KFZ58_12000(menH)

LAO:	AOX59_00685

LEX:	Len3610_09280(menH)

SJE:	AAV35_004060

APAK:

AP3564_09480

ACOP:

RI196_04770(menH)

BSJ:	UP17_22185

BMUR:

ABE28_020805

PBUT:

DTO10_08630(menH)

PASA:

BAOM_4225(menH)

PPSR:

I6J18_17805(menH)

PFRI:

L8956_23655(menH)

AQT:	FN924_12525(menH)

RAX:	KO561_13330(menH)

BTHV:

CQJ30_04985(menH)

PSYH:

D0S48_19110(menH)

PSYO:

PB01_13540(menH)

PSYB:

KD050_04015(menH)

PRD:	F7984_15740(menH)

GRC:	GI584_09610(menH)

GCS:	MUN88_18910(menH)

GSM:	MUN87_00115(menH)

POF:	GS400_15565(menH)

PCHU:

QNI29_16700(menH)

NMK:	CHR53_21790(menH)

NTM:	BTDUT50_13760(menH)

NDT:	L1999_23645(menH)

NCM:	QNK12_24915(menH)

NNV:	QNH39_20970(menH)

MEKU:

HUW50_02925(menH)

MSEM:

GMB29_21595(menH)

MDG:	K8L98_19940(menH)

MLIT:

KDJ21_011075(menH)

BLEN:

NCTC4824_03197(menH)

SEDD:

ERJ70_13170(menH)

BVQ:	FHE72_18655(menH)

RMF:	D5E69_17020(menH)

RAZ:	U9J35_18275(menH)

BCK:	BCO26_2089

BAG:

Bcoa_2399

BCOA:

BF29_1161(menH)

BVJ:	I5776_06430(menH)

BOU:	I5818_07630(menH)

CTHU:

HUR95_10780(menH)

MCUI:

G8O30_10220(menH)

GAJ:	MY490_03570(menH)

MJO:	FOF60_19375(menH)

MSUT:

LC048_03015(menH)

FHL:	OE105_09225(menH)

FAF:	OE104_01470(menH)

SFOR:

QNH23_01870(menH)

ECTO:

MUG87_09975(menH)

TEI:	QS257_15420

ALKG:

MOJ78_15875(menH)

PHJ:	LC071_06230(menH)

DOM:	RRU94_12935(menH)

STEA:

C0679_07655(menH)

PUK:	PU629_17915(menH)

SA0897

SAV:

SAV1044

SAW:

SAHV_1037

SAH:	SaurJH1_1126

SAJ:	SaurJH9_1103

SAM:

MW0928

SAS:

SAS0980

SAR:

SAR1018

SAC:

SACOL1053

SAX:	USA300HOU_0992

SAA:	SAUSA300_0947

SAO:	SAOUHSC_00984

SAE:

NWMN_0914

SAD:

SAAV_1008

SUU:	M013TW_0974(menH)

SUV:	SAVC_04390

SUE:

SAOV_0990

SUJ:	SAA6159_00901(menH)

SUK:	SAA6008_00999(yfbB)

SUC:

ECTR2_900

SUT:	SAT0131_01079

SUQ:	HMPREF0772_12190(menH)

SUZ:	MS7_1002(menH)

SUD:	ST398NM01_1042

SUX:	SAEMRSA15_08760

SUW:	SATW20_10410

SUG:

SAPIG1042

SUF:	SARLGA251_09590

SAUA:

SAAG_02155

SAUE:

RSAU_000933(menH)

SAUN:

SAKOR_00965

SAUS:

SA40_0915

SAUU:

SA957_0930

SAUG:

SA268_0932

SAUZ:

SAZ172_0985

SAUT:

SAI1T1_2007380

SAUJ:

SAI2T2_1007400

SAUK:

SAI3T3_1007390

SAUQ:

SAI4T8_1007380

SAUV:

SAI7S6_1007390

SAUW:

SAI5S5_1007350

SAUX:

SAI6T6_1007360

SAUY:

SAI8T7_1007390

SAUF:

X998_1044(menH)

SAB:

SAB0911

SUY:	SA2981_0999

SAUB:

C248_1069

SAUM:

BN843_9510

SAUC:

CA347_961(menH)

SAUR:

SABB_03583

SAUI:

AZ30_04985

SAUD:

CH52_00660

SAMS:

NI36_04995

SUH:	SAMSHR1132_08930

SER:

SERP0631

SEP:

SE_0745

SEPP:

SEB_00721

SEPS:

DP17_2078(menH)

SHA:

SH1918

SHH:	ShL2_01781(yfbB_2)

SSP:

SSP1747

SCA:

SCA_0653

SLG:	SLGD_01828

SLN:	SLUG_18240

SSD:	SPSINT_0741

SDT:

SPSE_1767

SDP:	NCTC12225_02004(menH)

SWA:	A284_08595

SPAS:

STP1_2105

SXY:	BE24_02545

SXL:	SXYLSMQ121_1748

SXO:	SXYL_01891(menH)

SHU:	SHYC_09130(menH)

SCAP:

AYP1020_0368(menH)

SSCH:

LH95_08550

SSCZ:

RN70_09030

SAGQ:

EP23_01295(menH)

SEQO:

SE1039_08030

SSIF:

AL483_06680(menH)

SCV:	A4G25_04665

SPET:

CEP67_00045(menH)

SLZ:	B5P37_09245

SCOH:

BZ166_00655

SNL:	BJD96_09690

SKL:	C7J89_10495(menH)

SFQ:	C7J90_06975(menH)

SHOM:

EGX58_01455(menH)

SMUS:

C7J88_00110(menH)

SCAR:

DWB96_09460(menH)

SCHR:

DWB92_08605(menH)

SARL:

SAP2_17820(menH)

SPIC:

SAMEA4384060_1911(menH)

SSH:	NCTC13712_00990(menH)

SSIM:

SAMEA4384339_0959(menH)

SDB:	CNQ82_05000(menH)

SLLO:

ISP08_08780(menH)

SAUL:

I6G39_08080(menH)

SSAC:

I6I31_07445(menH)

SRAI:

LN051_08015(menH)

SPSD:

JMB28_09460(menH)

STAS:

HYI43_08980(menH)

SURY:

MUA21_03725(menH)

SEDA:

MNY58_09370(menH)

SCAQ:

QMO72_09405(menH)

SDEV:

Q2T90_10415(menH)

SROT:

ML435_04740(menH)

STAP:

AOB58_958

SSCU:

CEP64_08460(menH)

SFF:	FOB90_10930(menH)

SSTE:

SAMEA4384403_1818(menH)

MLEN:

H3V22_13515(menH)

MVT:	I6J10_02240(menH)

MACR:

BHM04_01225

MARY:

LAU42_08480(menH)

MBRU:

MGG13_08465(menH)

MEPI:

KFV12_10115(menH)

MBOC:

QSV55_08485(menH)

MCL:

MCCL_1506

MCAK:

MCCS_19420(menH)

MBOE:

HT586_09445(menH)

SHV:	AAT16_08895

JEA:	JEM45_00550(menH)

NAMP:

KPF49_05275(menH)

NMY:	CJ229_003115(menH)

SBAC:

BVH56_06225

LMO:

lmo1674

LMN:	LM5578_1821

LMY:	LM5923_1773

LMT:	LMRG_01293

LMOC:

LMOSLCC5850_1737

LMOE:

BN418_1981

LMOB:

BN419_1984

LMOD:

LMON_1741

LMOW:

AX10_02465

LMOQ:

LM6179_02425(menH)

LMR:	LMR479A_1773(ytxM)

LMOM:

IJ09_01605

LMF:	LMOf2365_1698

LMC:	Lm4b_01687

LMOG:

BN389_17020(ytxM)

LMP:

MUO_08610

LMOL:

LMOL312_1681

LMOJ:

LM220_15890

LMOZ:

LM1816_09767(menH)

LMOX:

AX24_05940

LMH:	LMHCC_0892

LMQ:

LMM7_1763

LML:	lmo4a_1731

LMG:	LMKG_02963

LMS:

LMLG_1198

LMJ:	LMOG_00011

LMW:	LMOSLCC2755_1686

LMX:	LMOSLCC2372_1739

LMZ:	LMOSLCC2482_1738

LMON:

LMOSLCC2376_1633

LMOS:

LMOSLCC7179_1647

LMOO:

LMOSLCC2378_1695

LMOY:

LMOSLCC2479_1737

LMOT:

LMOSLCC2540_1757

LMOA:

LMOATCC19117_1689

LMOK:

CQ02_08585

LMV:	Y193_07315(menH)

LIN:

lin1782

LWE:

lwe1692

LSG:

lse_1642

LIV:

LIV_1649

LII:	JL52_08620

LIW:	AX25_08780

LIA:	JL58_08765

LIO:	JL53_09230

LWI:	UE46_10310

LMAR:

LAX80_008035(menH)

LNW:	OTR81_11260(menH)

BTHS:

CNY62_10555(menH)

ESI:

Exig_0626

EAT:	EAT1b_2373

EAN:

Eab7_0601

EXU:	ESP131_05695

EAP:	KB235_13605

EACE:

KKI46_03465(menH)

EMM:	PTI97_02910

EPF:	OE059_11830

PLIG:

NAG76_06625(menH)

AAC:

Aaci_1917

AAD:	TC41_2016(menH)

AFX:	JZ786_15845(menH)

AACO:

K1I37_13160(menH)

ACUR:

JZ785_04855(menH)

ADAU:

NZD86_10100(menH)

AFAS:

NZD89_11740(menH)

ACYC:

JI721_14605(menH)

EFF:	skT53_12940(menH)

SIV:

SSIL_1097

SSIL:

SOLI23_12790

SOB:	CSE16_16465(menH)

PLN:	Plano_0991

PKU:	AUO94_11100

PRT:	AUC31_03905

PLL:	I858_001945

PANA:

BBH88_14975

PDG:	BCM40_10435

PHC:	BBI08_01665

PMAR:

B0X71_06375

PPLA:

BBI15_01845

PFAE:

AJGP001_06120

PLX:	CW734_07575(menH)

PMAT:

BBI11_06990

PDEC:

H1Q58_06155(menH)

PGQ:	FK545_14295(menH)

JEO:

JMA_25500

KUR:	ASO14_771(menH)

KZO:	NCTC404_02969(menH)

SPSY:

AZE41_05375

SPOR:

SporoP33_03500

SPOP:

SporoP37_04200

SURE:

SporoP32a_04060

SPOS:

DV702_07790(menH)

SPAE:

E2C16_01655(menH)

SPOO:

J3U78_07675(menH)

SURL:

BI350_05320

STHO:

QNH10_10120(menH)

RST:	ATY39_09565

PAEK:

D3873_08450(menH)

PANC:

E2636_05435(menH)

PLAY:

DNR44_014550(menH)

VIJ:	JNUCC6_10265(menH)

UTH:	DKZ56_12390(menH)

NTR:	B0W44_12855

KPUL:

GXN76_04690(menH)

KEB:	GXN75_05410(menH)

LLA:	L0170(menX)

LLK:	LLKF_0750(menX)

LLT:	CVCAS_0692(menX)

LLS:	lilo_0662(menX)

LLD:	P620_04020(menH)

LLX:	NCDO2118_0746(menX)

LLJ:	LG36_0712(menX)

LLM:	llmg_1830(menX)

LLC:

LACR_0772

LLR:

llh_9215

LLN:	LLNZ_09415

LLI:	uc509_0736(menX)

LLW:	kw2_0679(menH)

LGR:

LCGT_0618

LGV:

LCGL_0637

LACT:

D7I46_01645(menH)

LTI:	JW886_04095(menH)

LPET:

lgb_01392(menH_3)

LFO:	LMK00_08075(menH)

LNG:	BSQ50_03285

LHW:	BSQ49_00425

LMAL:

LM596_00620(menH)

FIX:	M8332_06415

FCLI:

M3M38_04790(menH)

FHIN:

M3M39_01720(menH)

FMT:	M3M35_04415(menH)

FCP:	M3M37_06725(menH)

LCY:	LC20004_02970

LPD:	AYR62_00645

LGN:	ABM34_02200

LBM:	DS830_07165(menH)

BOG:	MOO47_03010(menH)

LME:

LEUM_0753

LMM:

MI1_03450

LMK:

LMES_0677

LCI:

LCK_00951

LKI:

LKI_00990

LEC:	LGMK_01695

LCN:	C270_03685

LGS:	LEGAS_0914(menH)

LGE:	C269_04505

LLF:	BCR17_07735

LGC:	A9176_07135

LSU:	A6B45_03640

LPSE:

FGL85_06675(menH)

WCE:

WS08_0959

WTR:	KHQ32_05380(menH)

WCT:

WS74_1025

WCI:	WS105_1021

WCB:	AO080_04610

WJO:	FOL01_1527

WPA:	CO680_01145(menH)

WCF:	C6P13_02325(menH)

WSO:	WSWS_01289(menH)

WHE:	EFA59_07050(menH)

WVR:	IE337_02135(menH)

EFA:

EF0449

EFL:

EF62_0768

EFI:	OG1RF_10334(menH)

EFD:	EFD32_0380

EFS:	EFS1_0329(menH)

EFN:	DENG_00435(menH)

EFQ:	DR75_2439(menH)

ENE:

ENT_25400

EHR:	EHR_11565 EHR_11570

ECAS:

ECBG_02740

EMU:	EMQU_1437(menH)

EGA:	AL523_00635(menH)

ESS:	ATZ33_13515

ETH:	CK496_06795(menH)

ECEC:

NCTC12421_02103(menH)

EIE:	ENLAB_09570(pip)

VTE:	BHY08_01925

VPI:	BW732_05290

VAC:	E4Z98_02335(menH)

VAO:	FA707_02445(menH)

VLC:	G314FT_02410(menH)

VIE:	OL234_07575(menH)

CML:	BN424_3100(menH)

CDJ:	BFC22_00600

CPAS:

Clopa_1998

CPAT:

CLPA_c25460

CPAE:

CPAST_c25460

OCW:	OW730_26695(menH)

DSY:

DSY0519

DHD:

Dhaf_0471

DDH:	Desde_1531

DMT:	DESME_13420

DED:	DHBDCA_p1036

DEC:	DCF50_p1092

DRS:	DEHRE_09650

SAY:	TPY_3628(menH)

SAP:	Sulac_1291

STHR:

BXT84_09745

HFV:	R50_0754(menH)

VGU:	HYG85_16735(menH)

ETM:	CE91St48_28600

TEB:	T8CH_1568(menH)

VPR:

Vpar_0375

VAT:	B7L28_01995

VRM:	44547418_00396(menH)

VDN:	NCTC11831_00357(menH)

VNK:	VEIT17_03700

VRG:	OKW85_01955(menH)

STED:

SPTER_12090(menH)

LPIL:

LIP_2424

CCU:	Ccur_14030

ELE:

Elen_2975

EYY:	EGYY_26910(MhpC)

EGD:	GS424_017055

AEQ:

AEQU_2027

AHAT:

ADCFC_23010

RTS:	CE91St31_31150(menH)

SGRF:

SGFS_040180

ACIT:

HPK19_21850(menH)

NCX:	Nocox_20370

ARHD:

VSH64_18820

ABAI:

IMCC26256_111892

RXY:

Rxyl_2894

RRD:	RradSPS_2312

RUB:	GBA63_16225(menH)

RMAR:

GBA65_16935(menH)

BSOL:

FSW04_15645

BALA:

DSM104299_02591(menH_1)

CWO:

Cwoe_3574

PARN:

NBH00_16430

PBAJ:

LRS13_16380(menH)

AFO:

Afer_1626

AYM:	YM304_23990(menH)

ATQ:	GH723_10675

AQZ:	KSP35_02185

IAM:	HC251_13710

DHI:	LH044_00370 LH044_16095

CMP:	Cha6605_3537

CYN:	Cyan7425_3399

CEP:	Cri9333_3868

AMR:

AM1_4012

LEN:	LEP3755_61050

LBO:	LBWT_47620

KOV:	K9N68_33680(menH)

LSK:	J5X98_22820(menH)

PSER:

ABRG53_3325

PGX:	OA858_20215(menH)

CHON:

NIES4102_16500

CYP:	PCC8801_3284

CYH:	Cyan8802_2839

CYJ:	Cyan7822_5848

TER:

Tery_4069

ARP:	NIES39_L00160

PAGH:

NIES204_07520

PPSU:

NO713_02479(menH)

PRUN:

PCC7821_00643(menH)

OXY:	HCG48_16750(menH)

MVAG:

D0A34_26165(menH)

LFS:	HFV01_02750(menH)

OAC:	Oscil6304_1887

ONI:	Osc7112_5498

MPRO:

BJP34_18160

MIC:	Mic7113_6109

ANA:

all2753

NPU:	Npun_R0088

NOS:	Nos7107_5170

NOP:	Nos7524_2259

NON:	NOS3756_37520

NFL:	COO91_04925

NOE:	CLI64_25165(menH)

NSH:

GXM_05680

NED:	HUN01_27490(menH)

NPZ:	ACX27_09645

AVA:

Ava_4319

NAZ:

Aazo_3702

ANB:	ANA_C11508

ACY:	Anacy_0915

AWA:	AA650_24575

ANN:	EH233_01835(menH)

CSG:	Cylst_5362

RSIN:

B6N60_01511

HBQ:	QI031_15270(menH)

CALO:

Cal7507_0974

CALT:

Cal6303_3133

CALH:

IJ00_14555

CALN:

NIES2098_09680

CALS:

NIES3974_44890

RIV:	Riv7116_6737

FIS:	FIS3754_30350

NSPH:

BDGGKGIB_02556(menH)

DOU:	BMF77_01613(menH)

DFS:	HGD76_09815(menH)

DHT:	NG743_11235(menH)

CCUR:

IAR63_04030(menH)

CRK:	L3I90_04480(menH)

AFLO:

HEQ12_19485(menH)

STOQ:

K2F26_19885(menH)

AEE:	IM676_06950(menH)

RCS:	NIES932_24450

TOQ:	HCG51_20005(menH)

ALAX:

NIES50_24490

NCN:	BZZ01_27585

SCS:	Sta7437_1787

STAN:

STA3757_23930

RRS:	RoseRS_4115

RCA:

Rcas_1310

CAU:

Caur_0087

CHL:	Chy400_0095

CAG:

Cagg_1168

PBF:	CFX0092_A0435(ytxM)

KBS:	EPA93_24685(menH)

KBB:	ccbrp13_15660 ccbrp13_55060(menH)

TBH:	Tbon_12775(menH)

TFLA:

O0235_14545(menH)

TTR:

Tter_1232

TRO:

trd_A0259

STI:

Sthe_3023

PCU:	PC_RS05140

PNL:	PNK_0813(menH)

PUV:

PUV_20290

NEY:	NCS13_1_0812

WCH:

wcw_1199

SNG:	SNE_A14240

RPOR:

RHAB15C_0000469

CAA:

Caka_1141

RUFI:

K0V07_11815

AMU:

Amuc_1017

AGL:

PYTT_0708

AMAK:

J5W79_04775

LUO:	HHL09_08635

LAMB:

KBB96_01040

SOA:	G3M56_005840

UAM:	UABAM_01397

SFOL:

H3H32_32055

CTE:	CT1845(menH)

CPC:

Cpar_0358

CLZ:	BIU88_10000

CCH:

Cag_1720

CPH:	Cpha266_2090

CPB:	Cphamn1_2076

CLI:

Clim_2049

PVI:

Cvib_0395

PLT:

Plut_0329

PPH:

Ppha_2432

PAA:

Paes_1879

PROC:

Ptc2401_01967(menH)

PRS:	B9H02_09445

PROS:

CHL67_10000(menH)

PROW:

OO006_02250(menH)

PROI:

OO005_02215(menH)

CTS:

Ctha_1988

RBAR:

AWN76_007285

IAL:	IALB_1319(menH)

MRO:

MROS_1449

CPRV:

CYPRO_1678

NALL:

PP769_08060

NNEO:

PQG83_19285

» show all

Reference

1 [PMID:18284213]

Authors

Jiang M, Chen X, Guo ZF, Cao Y, Chen M, Guo Z.

Title

Identification and Characterization of (1R,6R)-2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate Synthase in the Menaquinone Biosynthesis of Escherichia coli.

Journal

Biochemistry 47:3426-34 (2008)
DOI:10.1021/bi7023755

Sequence

[eco:b2263]

Reference

2 [PMID:17760421]

Authors

Jiang M, Cao Y, Guo ZF, Chen M, Chen X, Guo Z.

Title

Menaquinone biosynthesis in Escherichia coli: identification of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a novel intermediate and re-evaluation of MenD activity.

Journal

Biochemistry 46:10979-89 (2007)
DOI:10.1021/bi700810x

Sequence

[eco:b2263]

Other DBs

ExplorEnz - The Enzyme Database:

4.2.99.20

IUBMB Enzyme Nomenclature:

4.2.99.20

ExPASy - ENZYME nomenclature database:

4.2.99.20

BRENDA, the Enzyme Database:

4.2.99.20

CAS:	122007-88-9

DBGET integrated database retrieval system