Entry
Name
3,4-dihydroxyphenylalanine reductive deaminase;
reductive deaminase;
DOPA-reductive deaminase;
DOPARDA
Class
Lyases;
Carbon-nitrogen lyases;
Ammonia-lyases
BRITE hierarchy
Sysname
3,4-dihydroxy-L-phenylalanine ammonia-lyase (3,4-dihydroxyphenylpropanoate-forming)
Reaction(IUBMB)
L-dopa + NADH = 3,4-dihydroxyphenylpropanoate + NAD+ + NH3 [RN:
R08846 ]
Reaction(KEGG)
Substrate
Product
Comment
Forms part of the L-phenylalanine-catabolism pathway in the anoxygenic phototrophic bacterium Rhodobacter sphaeroides OU5. NADPH is oxidized more slowly than NADH.
History
EC 4.3.1.22 created 2007
Pathway
Reference
Authors
Ranjith NK, Sasikala Ch, Ramana ChV.
Title
Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 4.3.1.22
ExPASy - ENZYME nomenclature database: 4.3.1.22