KEGG ENZYME: 4.3.2.9

ENZYME: 4.3.2.9

Entry

EC 4.3.2.9                  Enzyme

Name

gamma-glutamylcyclotransferase;
gamma-glutamyl-amino acid cyclotransferase;
gamma-L-glutamylcyclotransferase;
L-glutamic cyclase;
(5-L-glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing);
GGCT

Class

Lyases;
Carbon-nitrogen lyases;
Amidine-lyases

Sysname

alpha-(gamma-L-glutamyl)-L-amino-acid gamma-glutamyl cyclotransferase (5-oxo-L-proline producing)

Reaction(IUBMB)

alpha-(gamma-L-glutamyl)-L-amino acid = alpha-L-amino acid + 5-oxo-L-proline [RN:R03749]

Reaction(KEGG)

R03749;
(other) R02743

Substrate

alpha-(gamma-L-glutamyl)-L-amino acid [CPD:C03740]

Product

alpha-L-amino acid;
5-oxo-L-proline [CPD:C01879]

Comment

The enzyme, found in animals and plants, acts on derivatives of L-glutamate, L-2-aminobutanoate, L-alanine and glycine. The enzyme acts as a cyclotransferase, cleaving the amide bond via transamidation using the alpha-amine of the L-glutamyl residue, releasing it as the cyclic 5-oxo-L-proline.

History

EC 4.3.2.9 created 1972 as EC 2.3.2.4, transferred 2017 to EC 4.3.2.9

Pathway

ec00480

Glutathione metabolism

ec01100

Metabolic pathways

Orthology

K00682

gamma-glutamylcyclotransferase

K22596

gamma-glutamylcyclotransferase, plant

Genes

HSA:	79017(GGCT)

PTR:	463327(GGCT)

PPS:	100984104(GGCT)

GGO:	101138956(GGCT)

PON:	100444244(GGCT)

NLE:	100600608(GGCT)

HMH:	116812600(GGCT)

MCC:	695547(GGCT)

MCF:	102142709(GGCT)

MTHB:

126950084

MNI:	105475810(GGCT)

CSAB:

103226276(GGCT)

CATY:

105596146(GGCT)

PANU:

100999777(GGCT)

TGE:	112621323(GGCT)

MLEU:

105533697(GGCT)

RRO:	104668447(GGCT)

RBB:	108533407(GGCT)

TFN:	117073666(GGCT)

PTEH:

111523630(GGCT)

CANG:

105520308(GGCT)

CJC:	100389077(GGCT)

SBQ:	101033297(GGCT)

CIMI:

108303312(GGCT)

CSYR:

103270036(GGCT)

MMUR:

105855110(GGCT)

LCAT:

123647040(GGCT)

PCOQ:

105807354(GGCT)

OGA:	100956580(GGCT)

MMU:	110175(Ggct)

MCAL:

110296364(Ggct)

MPAH:

110316963(Ggct)

RNO:	362368(Ggct)

MCOC:

116098953(Ggct)

ANU:	117720627(Ggct)

MUN:	110555071(Ggct)

CGE:	100774679(Ggct)

MAUA:

101841471(Ggct)

PROB:

127235656(Ggct)

PLEU:

114689711(Ggct)

MORG:

121439724(Ggct)

MFOT:

126509592

AAMP:

119807043(Ggct)

NGI:	103740842(Ggct)

HGL:	101723887(Ggct)

CPOC:

100723170(Ggct)

CCAN:

109701127(Ggct)

DORD:

105999985(Ggct)

DSP:	122120878(Ggct)

PLOP:

125346733(Ggct)

NCAR:

124990841

MMMA:

107146145(Ggct)

OCU:

100337901

OPI:	101533005(GGCT)

TUP:	102497631(GGCT)

GVR:	103597342(GGCT)

CFA:	611603(GGCT)

CLUD:

112670666(GGCT)

VVP:	112935405(GGCT)

VLG:	121475140(GGCT)

NPO:	129502852(GGCT)

AML:	100475961(GGCT)

UMR:	103658939(GGCT)

UAH:	113262388(GGCT)

UAR:	123789108(GGCT)

ELK:

111147302

LLV:

125081184

MPUF:

101682326(GGCT)

MNP:	132015824(GGCT)

MLK:	131829579(GGCT)

NVS:	122904955(GGCT)

ORO:	101381331(GGCT)

EJU:	114221157(GGCT)

ZCA:	113911457(GGCT)

MLX:	118020929(GGCT)

NSU:	110577369 110579985(GGCT)

LWW:	102745356(GGCT)

FCA:	101087219(GGCT)

PYU:	121028528(GGCT)

PCOO:

112866712(GGCT)

PBG:	122488064(GGCT)

PVIV:

125161309(GGCT)

LRUF:

124524955

PTG:	102972301(GGCT)

PPAD:

109263921(GGCT)

PUC:

125930028

AJU:

106968672

HHV:	120230344(GGCT)

BTA:	533374(GGCT)

BOM:	102265622(GGCT)

BIU:	109557476(GGCT)

BBUB:

102412357(GGCT)

BBIS:

104980527(GGCT)

CHX:	102187188(GGCT)

OAS:	101102474(GGCT)

BTAX:

128047003(GGCT)

ODA:	120877398(GGCT)

CCAD:

122438426(GGCT)

MBEZ:

129552486(GGCT)

SSC:	100512447(GGCT)

CFR:	102512131(GGCT)

CBAI:

105081920(GGCT)

CDK:	105095846(GGCT)

VPC:	102542935(GGCT)

BACU:

102997196(GGCT)

BMUS:

118901081(GGCT)

LVE:	103085194(GGCT)

OOR:	101278558(GGCT)

DLE:	111180063(GGCT)

PCAD:

102983283(GGCT)

PSIU:

116759010(GGCT)

NASI:

112406298(GGCT)

ECB:	100069874(GGCT)

EPZ:

103552750

EAI:	106831060(GGCT)

MYB:	102257993(GGCT)

MYD:	102766806(GGCT)

MMYO:

118666061(GGCT)

MLF:	102436341(GGCT)

PKL:	118727813(GGCT)

EFUS:

103291542(GGCT)

MNA:	107544417(GGCT)

DRO:	112306962(GGCT)

SHON:

118983562(GGCT)

AJM:	119035259(GGCT)

PDIC:

114508089(GGCT)

PHAS:

123811697(GGCT)

MMF:	118620042(GGCT)

PPAM:

129068886(GGCT)

HAI:	109381318(GGCT)

RFQ:	117012093(GGCT) 117028261

PALE:

102887499(GGCT)

PGIG:

120602408(GGCT)

PVP:	105308613(GGCT)

RAY:	107499554(GGCT)

MJV:	108410147 118966933

TOD:	119244102(GGCT)

SARA:

101551902(GGCT)

LAV:	100673070(GGCT)

TMU:

101349289

ETF:	101651050(GGCT)

DNM:	101436405 101447508(GGCT)

MDO:	100032519(GGCT)

GAS:	123250462(GGCT)

SHR:	100919793(GGCT)

AFZ:

127539294

PCW:	110213108(GGCT)

OAA:	100081401(GGCT)

GGA:	420676(GGCT)

PCOC:

116227149(GGCT)

MGP:	100550241(GGCT)

CJO:	107309325(GGCT)

TPAI:

128086900(GGCT)

LMUT:

125696486(GGCT)

NMEL:

110394942(GGCT)

APLA:

101805349(GGCT)

ACYG:

106046640(GGCT)

CATA:

118249596(GGCT)

AFUL:

116486552(GGCT)

TGU:	100190607(GGCT)

LSR:	110468221(GGCT)

SCAN:

103813162(GGCT)

PMOA:

120503975(GGCT)

OTC:	121337610(GGCT)

PRUF:

121353197(GGCT)

GFR:	102039424(GGCT)

FAB:	101818892(GGCT)

OMA:	130250068(GGCT)

PHI:	102099497(GGCT)

PMAJ:

107200351(GGCT)

CCAE:

111923889(GGCT)

CCW:	104689028(GGCT)

CBRC:

103615885(GGCT)

ETL:	114064384(GGCT)

ZAB:	102072814(GGCT)

ACHL:

103798783(GGCT)

SVG:	106854490(GGCT)

MMEA:

130577396(GGCT)

HRT:	120753872(GGCT)

FPG:	101921074(GGCT)

FCH:	102047880(GGCT)

CLV:	102083440(GGCT)

EGZ:	104127521(GGCT)

NNI:	104018492(GGCT)

PLET:

104616011(GGCT)

PCAO:

104041891(GGCT)

ACUN:

113477173(GGCT)

TALA:

104368926(GGCT)

PADL:

103917094(GGCT)

AFOR:

103902512(GGCT)

ACHC:

115339007(GGCT)

HALD:

104312871(GGCT)

HLE:	104828613(GGCT)

AGEN:

126045805

GCL:

127012684

CCRI:

104156624(GGCT)

CSTI:

104551715(GGCT)

MUI:	104535429(GGCT)

BREG:

104631158(GGCT)

GSTE:

104253001(GGCT)

LDI:	104341910(GGCT)

MNB:	103776875(GGCT)

OHA:	104332665(GGCT)

NNT:	104400860(GGCT)

SHAB:

115613484(GGCT)

DPUB:

104306994(GGCT)

PGUU:

104460292(GGCT)

ACAR:

104519605(GGCT)

CPEA:

104397606(GGCT)

AVIT:

104268292(GGCT)

CVF:	104281578(GGCT)

RTD:	128905136(GGCT)

CUCA:

104068821(GGCT)

TEO:	104371333(GGCT)

BRHI:

104492564(GGCT)

AAM:	106491250(GGCT)

AROW:

112967160(GGCT)

NPD:	112952612(GGCT)

TGT:	104566525(GGCT)

DNE:	112982411(GGCT)

SCAM:

104152515(GGCT)

ASN:	102385482(GGCT)

AMJ:	102567732(GGCT)

CPOO:

109311129(GGCT)

GGN:	109291730(GGCT)

PSS:	102455884(GGCT)

CMY:	102934944(GGCT)

CCAY:

125631673(GGCT)

DCC:	119851839(GGCT)

CPIC:

101951537(GGCT)

TST:	117872437(GGCT)

CABI:

116827003(GGCT)

MRV:	120399512(GGCT)

ACS:	100558545(ggct)

ASAO:

132778648(GGCT)

PVT:	110082168(GGCT)

SUND:

121935638(GGCT)

PBI:	103053081(GGCT)

PMUR:

107294022(GGCT)

CTIG:

120305005(GGCT)

TSR:	106545488(GGCT)

PGUT:

117656101(GGCT)

APRI:

131196710(GGCT)

PTEX:

113447525(GGCT)

NSS:	113428970(GGCT)

VKO:	123016594(GGCT)

PMUA:

114607207(GGCT)

PRAF:

128398286(GGCT)

ZVI:	118091808(GGCT)

HCG:	128329967(GGCT)

GJA:	107111522(GGCT)

STOW:

125441373(GGCT)

EMC:	129337838(GGCT)

XLA:	108701001 108719977

XTR:	613056(ggct)

NPR:	108791133(GGCT)

RTEM:

120913573(GGCT)

BBUF:

121002124(GGCT)

BGAR:

122938406(GGCT)

MUO:	115472104(GGCT)

GSH:	117353761(GGCT)

DRE:	100149204(ggcta) 406278(ggctb)

SRX:	107709544 107714254 107751821

SANH:

107655114 107659081 107673341

SGH:	107557442 107565307 107601985

CCAR:

109102943 109107899(ggct)

CAUA:

113062554 113115779

CGIB:

127935239 127974506

PTET:

122335163(ggcta) 122360077(ggctb)

LROH:

127178544(ggctb) 127181797(ggcta)

OMC:	131521398(ggctb) 131526373(ggcta)

PPRM:

120471172(ggctb) 120483458(ggcta)

RKG:	130078424(ggcta) 130091533(ggctb)

MAMB:

125243691(ggctb) 125275851(ggcta)

CIDE:

127497678 127500967

MASI:

127425250 127453208 127453673

TROS:

130558042(ggctb) 130566575(ggcta)

TDW:	130415264(ggcta) 130432758(ggctb)

MANU:

129448901(ggctb) 129455934(ggcta)

IPU:	100528263(ggctb) 108256920(ggcta)

IFU:	128600449(ggcta)

PHYP:

113525565 113536025(ggct)

SMEO:

124375698(ggcta) 124403746(ggctb)

TFD:	113661467(ggcta)

TVC:	132863926(ggcta)

AMEX:

103033278 103036016

CMAO:

118799091(ggctb) 118806177(ggcta)

EEE:	113571945 113590649

CHAR:

105903728(ggcta) 105910028(ggctb)

TRU:	101065518 101077496

TFS:	130517897(ggcta) 130532630(ggctb)

TNG:	GSTEN00017404G001 GSTEN00021982G001

LCO:	104937169(ggct)

NCC:	104963997(ggct)

TBEN:

117477995(ggcta)

CGOB:

115016263(ggct)

PGEO:

117451113 117451395 117455238

GACU:

117555219(ggctb) 117562900(ggcta)

EMAC:

134862008(ggctb) 134874771(ggcta)

ELY:	117263598(ggcta) 117264499(ggctb)

EFO:	125892887(ggctb) 125904973(ggcta)

PLEP:

121945344(ggctb) 121965390

SLUC:

116047477(ggcta) 116066659(ggctb)

ECRA:

117946539(ggctb) 117957359(ggcta)

ESP:	116691364 116701262

PFLV:

114557381 114567936

GAT:	120826125(ggcta)

PPUG:

119197695(ggctb) 119219422(ggcta)

AFB:	129097357(ggcta) 129109241(ggctb)

CLUM:

117727946(ggctb) 117739422(ggcta)

PSWI:

130194512(ggcta)

MSAM:

119896837(ggctb) 119907115(ggcta)

SCHU:

122863929(ggcta) 122880964(ggctb)

CUD:	121523347(ggcta)

ALAT:

119006214(ggctb) 119016635(ggcta)

MZE:	101475529 101483555

ONL:	100703332 100712042

OAU:	116312060(ggcta) 116318459(ggctb)

OLA:	101162615 101170211

OML:	112139477(ggctb) 112160429(ggcta)

CSAI:

133424133 133440834 133461518(ggcta)

XMA:	102218941 102224050

XCO:	114152740 114156261

XHE:	116716788 116731276

PRET:

103472371 103478774

PFOR:

103129844 103135107

PLAI:

106938332 106949292

PMEI:

106912476 106918604

GAF:	122830665(ggctb) 122843621(ggcta)

PPRL:

129353761(ggctb) 129375138(ggcta)

CVG:	107092462 107100568

CTUL:

119792168(ggctb) 119795304(ggcta)

GMU:	124878982(ggcta)

NFU:	107379004 107397246 107397248

KMR:	108240813(ggcta) 108250051

ALIM:

106515801 106531193

NWH:	119425359(ggcta)

AOCE:

111563780 111569446(ggct)

MCEP:

125016602(ggctb) 125020163(ggcta)

CSEM:

103388762(ggct) 103394438

POV:	109631635 109631991

SSEN:

122774245(ggctb) 122786506

HHIP:

117770164(ggcta) 117777335(ggctb)

HSP:	118113916(ggctb) 118124376(ggcta)

SMAU:

118284693(ggctb) 118292103(ggcta)

LCF:	108886121 108898169(ggcta)

SDU:	111223418 111227777

SLAL:

111657536(ggct) 111659351 111664184

XGL:	120783928(ggctb) 120786303(ggcta)

HCQ:	109516380 109521920(ggct)

SSCV:

125975220 125986921

SBIA:

133501501(ggcta)

PEE:	133395697 133401971

PTAO:

133471207 133479709

BPEC:

110167470 110173791

MALB:

109963956(ggct)

BSPL:

114865528(ggcta)

SJO:	128366887(ggctb) 128373679

SASA:

100196182(cg024) 106579600 106588758 106605510(ggct)

STRU:

115173880 115177047 115181724

OTW:	112227899 112236468(ggctb) 112244893 112264468(ggcta)

OMY:	110496513(ggcta) 110511884 110539228(ggctb) 118938772

OGO:	123997174(ggctb) 124005857 124013326(ggcta)

ONE:	115114447 115114455 115128635 115140908

OKI:	109901755 109901860 109907306

OKE:	118364592 118372610 118372611 118399569(ggcta)

SALP:

111956202 111964720 111964926(ggct) 112068927

SNH:	120022529(ggcta) 120031141 120047202 120048522

CCLU:

121542388 121543020 121585463 121585640(ggcta)

ELS:	105009435 105012454 105019182

SFM:

108942523

PKI:	111846953 111848848 111848849

AANG:

118212318(ggctb) 118234751(ggcta)

LOC:	102683461 102697437

PSPA:

121312895

ARUT:

117399772

PSEX:

120515451(ggcta)

LCM:	102345575 102348398(GGCT)

CMK:	103176267(ggct)

RTP:

109924666

CPLA:

122564400

HOC:

132832107

LERI:

129708985

BFO:

118417214

SCLV:

120342021 120344808

LPIC:

129253967 129253974 129270622 129270636 129270690

APLC:

110981324 110981356

AJC:	117123460 117123515

SKO:	100369875 100374636 102801350

DER:	6546302 6546438

DSI:	Dsimw501_GD12343(Dsim_GD12343) Dsimw501_GD12344(Dsim_GD12344)

DYA:	Dyak_GE22074 Dyak_GE22075

DSR:	110178935 110178952

DPO:	4813359 4813554

DPE:	6599030 6599031

DMN:	108153030 108153031

DWI:	6645562 6645563

DMO:	Dmoj_GI11714 Dmoj_GI11715

DAZ:	108612658 108612672

DNV:	108650523 108650528

DHE:	111599245 111599248

DVI:

6622212

MDE:	101889641 101898676

LCQ:	111675218 111675233

AGA:

1272591

ACOZ:

120960119

AARA:

120899701

AAG:

5570054

AALB:

109405475

CQU:	CpipJ_CPIJ008797

CPII:

120416669

AME:

725055

ACER:

108000680

ALAB:

122711016

ADR:

102681207

AFLR:

105735671

BIM:

100745685

BBIF:

117207746

BVK:

117243262

BVAN:

117154961

BTER:

100643954

BAFF:

126923255

BPYO:

122574820

BPAS:

132913665

FVI:

122528076

CCAL:

108629753

OBB:

114876242

OLG:

117609361

MGEN:

117226300

NMEA:

116425686

CGIG:

122404271

SOC:

105196864

MPHA:

105835327

AEC:

105150314

ACEP:

105621528

PBAR:

105431273

VEM:

105566080

HST:

105183396

DQU:

106751798

CFO:	112639205 112639212

FEX:

115238427

LHU:

105674071

PGC:

109853083

OBO:

105279351

PCF:

106793959

PFUC:

122521446

VPS:

122628419

VCRB:

124433115

VVE:

124947878

NVI:	100122138 100122156

CSOL:

105361426

TPRE:

106658159

MDL:	103578586 103578587 103578589

CGLO:

123269340

CINS:

118067007

TCA:

657379

DPA:

109535153

SOY:

115880219

AGRG:

126746161

ATD:	109598827 109602561

CSET:

123313619

LDC:

111508184

NVL:

108569857

APLN:

108734187

BMOR:

101743698 110385885

BMAN:

114247235 114247236

MSEX:

115443784

DPL:	KGM_215639 KGM_215777

PMAC:

106717573 106717575

PPOT:

106100348 106100573

PXU:	106124195 106124282

PRAP:

111003918

ZCE:	119829328 119829671

HAW:	110377769 110377784 110377792

TNL:	113501842 113501843 113501844

SLIU:

111353384

PXY:	105396775 105396923 105396942

PGW:

126380387

CCRN:

123305728 123305791

API:

100160827

DNX:

107167438

AGS:

114123987

RMD:

113560882

ACOO:

126845584

DVT:

126902746

BTAB:

109031362

DCI:

103512087

CLEC:

106662315 106670618

NLU:

111061213

HVI:	124355419 124370945

MQU:

128996831

PHU:	Phum_PHUM041020

FOC:

113206849

TPAL:

117642591

ZNE:

110832632

CSEC:

111875463

BROR:

134542485

FCD:

110862377

DPX:	DAPPUDRAFT_303711

DMK:

116916916

DPZ:

124314269

PVM:

113828393

PJA:

122248962

PCHN:

125041435

PMOO:

119591916

HAME:

121866518 121870035

PCLA:

123774182

CQD:

128694455

PTRU:

123498548

ESN:

127001708

HAZT:

108674748

EAF:

111700289

LSM:

121125869

TCF:

131889355

PPOI:

119098864

DSV:

119432428

RSAN:

119376671 119404896

RMP:	119181365 119181366

TUT:

107359593

DFR:

124491626

CSCU:

111625598

PTEP:

107456735

ABRU:

129963705 129974869

UDV:

129230633

LPOL:

106457319

PMEO:

129588779

CEL:	CELE_C44B7.7(C44B7.7)

CBR:

CBG_11175

CRQ:	GCK72_006362

NAI:	NECAME_13395

LOA:	LOAG_08543

HRO:	HELRODRAFT_186293

LGI:	LOTGIDRAFT_123575 LOTGIDRAFT_164301

PVUL:

126815137

PCAN:

112576588

BGT:	106062447 106069328 106069361

GAE:

121371862

HRF:	124147247 124147279 124147280

HRJ:	124292196 124292221 124292232

CRG:

105327160

CVN:

111134893

CANU:

128188128

OED:

125648878

MYI:	110466847 110466858

PMAX:

117337406

MCAF:

127701431

MMER:

123550318 123550319

RPHI:

132715286

DPOL:

127845240

OBI:	106878407 106882979

OSN:	115213134 115213150

LAK:

106170080

SMM:	Smp_098340

SHX:	MS3_00010282

NVE:

5518185

EPA:	110243206 110246329

ATEN:

116286406

ADF:

107327495

AMIL:

114951909 114952501

PDAM:

113664494 113677322

SPIS:

111333813 111338839

HSY:

130649547

TAD:	TRIADDRAFT_20381

AQU:

100640069

ATH:	AT1G44790 AT4G31290 AT5G26220

ALY:	9305409 9310372 9327358

CRB:	17878856 17882261 17898278

CSAT:

104706945 104717066 104721711 104730170 104736648 104757964 104771108 109124741

EUS:	EUTSA_v10004888mg EUTSA_v10011803mg EUTSA_v10026164mg

BRP:	103834622 103837115 103847733 103851987

BNA:	106354720 106364013 106375433 106381093 106386242 106397053 106424106 106444452

BOE:	106296270 106303209 106316472 106332741 106342556

RSZ:	108821926 108825773 108825774 108828905 108833700 108844319 130507342

THJ:	104811222 104813146 104819923

CPAP:

110816712 110825227

CIT:	102621501 102624007

CIC:	CICLE_v10002572mg CICLE_v10009681mg

PVY:	116113062 116139717

MINC:

123194056 123228869

TCC:	18587580 18587748 18592315

GRA:	105773070 105774461 105787418

GHI:	107893895 107901405 107930786 107932947 107959977 107962505

GAB:	108470497 108484627 108485529

HSYR:

120150067 120173541 120212226

DZI:	111286390 111315625

EGR:	104437272 104450944

GMX:	100305985 100778704 100793027

GSJ:	114380872 114409059 114415082

PVU:	PHAVU_008G163900g PHAVU_009G103300g

VRA:	106760885 106764169

VAR:	108330026 108337478

VUN:	114164739 114193777

VUM:	124821495 124846567 124846568

CCAJ:

109796148 109796453 109798174

APRC:

113847740 113865395

MTR:	11417927 11427354 11432265

TPRA:

123898214 123902103

CAM:	101511126 101514800

PSAT:

127085181 127095800

VVO:	131595987 131600436 131654718 131654732

LJA:	Lj1g3v1991800.1(Lj1g3v1991800.1) Lj1g3v4314270.1(Lj1g3v4314270.1)

ADU:	107469832 107470940

AIP:	107622968 107623752

AHF:	112715651 112716197 112783003 112784304

LANG:

109326518 109327376 109344182 109359215

PCIN:

129294298 129294613 129299142 129303074

QSA:	O6P43_015198 O6P43_015563 O6P43_019330

FVE:	101301837 101304934 105350857

RCN:	112169047 112174395

PPER:

18788851 18790271

PMUM:

103319845 103320123

PAVI:

110750525 110761222

PDUL:

117621777 117638595

MDM:	103424725 103441211 103450651

MSYL:

126604283 126632224 126632251

PXB:	103938071 103953177 103957519 103964523

ZJU:	107404632 107429933

MNT:	21402790 21405139

CSAV:

115700246 115718589 115720614

CSV:	101208455 101209842 101217290

CMO:	103488216 103503734 103504050

BHJ:	120075179 120075407 120084920

MCHA:

111005209 111011188 111011785

CMAX:

111476702 111480746 111487769 111491933 111496304

CMOS:

111443344 111446683 111454251 111459557 111462945

CPEP:

111788277 111790483 111797190 111798504 111805026

RCU:	8274106 8282096

JCU:	105637441 105638920

HBR:	110640417 110654001

MESC:

110603046 110606600

POP:	18100791 18107563 7469146

PEU:	105107220 105109830 105112611

PALZ:

118029315 118030654 118055722 118059469

JRE:	108992156 109009548

CILL:

122313440 122317099

CAVE:

132167035 132189659

QSU:	112012644 112015572 112015980 112032345

QLO:	115960247 115972252

TWL:	119996263 120006465 120010594

VVI:	100261255 100264430

VRI:	117906131 117911979

SLY:	101246397 101258241 101259958

SPEN:

107003194 107005374 107026636

SOT:	102578210 102584350 102592696 102603766

SSTN:

125841927 125843627 125863162

SDUL:

129882357 129888864 129902764

CANN:

107849334 107851197 107868061

LBB:	132604272 132609539 132627011

NTA:	107779373 107779408 107780043 107789157 107789186 107813044

NSY:	104221251 104226848 104246856

NTO:	104090560 104105646 104120800

NAU:	109205458 109213980 109238253

INI:	109162618 109191401

ITR:	115995816 116032162

SIND:

105159476 105160644 105164943

OEU:	111380792 111380821 111385982 111398212

EGT:	105972991 105975356

SSPL:

121746164 121751589 121753706 121758269 121779078 121780432 121780781 121784005

SMIL:

130987210 131015072 131024087

SHIS:

125189200 125211740 125211910 125222976

APAN:

127250296 127255615 127256073 127265628

HAN:	110885602 110899266 110930152

ECAD:

122580292 122599451

LSV:	111904171 111908087

CCAV:

112510820 112529281

DCR:	108205073 108206540 108221913

CSIN:

114286208 114311236

RVL:	131301546 131307548

AEW:	130764530 130787636 130794065

BVG:	104886716 104891090

SOE:	110783915 110797987

CQI:	110696276 110709595 110710198 110728547

ATRI:

130797775 130809677

MOF:	131152108 131163136

NNU:	104601638 104609647

MING:

122071607 122079645

TSS:	122653581 122661978

PSOM:

113300000 113346330 113356209 113358780

OSA:	4329321 4335982

DOSA:

Os02t0465900-01(Os02g0465900) Os04t0448600-01(Os04g0448600)

OBR:	102712078 102720950

OGL:	127763422 127769652

BDI:	100832571 100833954

ATS:	109743898 109782856

TDC:	119314497 119322790 119329206 119355292 119364426

TAES:

123045600 123053442 123131885 123135861 123143384 123189350

TUA:

125538438

LPER:

127312657 127335044

LRD:	124674619 124676152 124683860 124684070

SBI:	110434709 8073384

ZMA:	100193117 100284213 103632484 109945950 109945951

SITA:

101768570 101779265

SVS:	117841535 117865446

PVIR:

120641158 120655690 120682803 120700942

PHAI:

112877649 112899877

PDA:	103697269 103700223 103701451 103702255

EGU:	105039351 105050450 105050890 105060924

MUS:	103973129 103976860 103977548 103991763 103996023

ZOF:	122002445 122006697 122009310 122017718 122020038 122022609 122032180 122034775 122034776

DCT:	110100720 110103744 110104628 110106274

PEQ:	110023085 110023425 110024594 110027757 110039043

AOF:	109821597 109842906 109848877

MSIN:

131217559 131242520

NCOL:

116249217 116262524

ATR:	18433775 18440759 18446481

SMO:	SELMODRAFT_48672 SELMODRAFT_58744 SELMODRAFT_58757 SELMODRAFT_85708

PPP:	112280397 112281175 112285362 112288003 112289734

CRE:	CHLRE_10g452000v5

VCN:	VOLCADRAFT_46802

CSL:	COCSUDRAFT_18395

CVR:	CHLNCDRAFT_12490

APRO:

F751_4836

OLU:	OSTLU_13383

OTA:	OT_ostta17g02340

BPG:	Bathy12g00210

MIS:	MICPUN_81834

MPP:	MICPUCDRAFT_43343(JGI:MicpuC2_43343)

PAN:	PODANSg4048

CTHR:

CTHT_0006380

MAW:

MAC_04864

MAJ:

MAA_00851

GLZ:	GLAREA_04058

PNO:	SNOG_12675

BZE:	COCCADRAFT_88969

BOR:	COCMIDRAFT_99394

PFJ:	MYCFIDRAFT_142157

FFU:	CLAFUR5_08410

BCOM:

BAUCODRAFT_229127 BAUCODRAFT_61477

PSQ:	PUNSTDRAFT_47894

LBC:	LACBIDRAFT_306191

CCI:	CC1G_01036

ABP:	AGABI1DRAFT111071(AGABI1DRAFT_111071) AGABI1DRAFT117923(AGABI1DRAFT_117923) AGABI1DRAFT124916(AGABI1DRAFT_124916)

ABV:	AGABI2DRAFT133726(AGABI2DRAFT_133726) AGABI2DRAFT176448(AGABI2DRAFT_176448)

MPR:	MPER_15124

MRR:

Moror_842

E1B28_009017

SRL:	SOD_c35260

SRY:	M621_19105

MLQ:	ASQ50_06240

MARA:

D0851_18355

CPS:

CPS_2442

COZ:	A3Q34_00555

PHA:

PSHAa0334

PTN:	PTRA_a0356

PBW:	D172_002105

PART:

PARC_a3561

PNG:	PNIG_a0384

PMAA:

CPA52_01840

PXI:	J5O05_06665

LAL:	AT746_01925

SALH:

HMF8227_00565

FBL:

Fbal_2422

NOC:

Noc_2712

TEE:

Tel_14445

APRS:

BI364_16385

NAX:	HC341_00775 HC341_01590

HAHE:

ENC22_05115

HAK:	KO116_02365

HAG:	BB497_01515 BB497_05160

HQD:	K1Y77_12640

HVN:	EI420_13115 EI420_13235

HOL:	HORIV_38510

HPIZ:

GYM47_02210

HNP:	SR894_10955

HTT:	HZS52_17580

MARD:

IBG28_12355 IBG28_12860

AJP:	AMJAP_1356

OME:	OLMES_2647

TSN:	W908_04880

BCT:

GEM_5817

PACP:

FAZ97_20230

HYL:	LPB072_20315

NLC:	EBAPG3_005780

MMYR:

MXMO3_01195 MXMO3_03588

SPKC:

KC8_09770

ADE:

Adeh_4028

ACP:	A2cp1_4170

ANK:	AnaeK_4144

MXA:

MXAN_3680

MSD:	MYSTI_04263

MFB:	MFUL124B02_22960

MFU:	LILAB_26540

CFUS:

CYFUS_005304

BBA:

Bd1350

BDC:	DOE51_06205

BDZ:	DOM22_07135

CCL:	Clocl_1731

COO:

CCU_03970

CCT:

CC1_08810

BLAB:

EYS05_05600

CGC:	Cyagr_2047

AMR:

AM1_4771

OXY:	HCG48_17840

DET:

DET1452

DEH:

cbdbA1418

DEB:	DehaBAV1_1254

DEV:	DhcVS_1231

DEG:	DehalGT_1163

DMC:

btf_1329

DMD:

dcmb_1310

DMG:

GY50_1283

DMX:	X792_06815

DMY:	X793_06665

DMZ:	X794_06250

DUC:	UCH007_12060

DLY:	Dehly_1401

DFO:	Dform_02141

DETH:

HX448_00665

MIN:

Minf_0575

RUL:

UC8_32080

PND:	Pla175_41700

GMR:	GmarT_37160

GIM:	F1728_27965

GPN:	Pan110_35450

MRI:	Mal4_08100

SDYN:

Mal52_44250

HBS:	IPV69_17615

MMAB:

HQ865_11595

MVU:	Metvu_1295

» show all

Reference

Authors

Bodnaryk, R.P. and McGirr, L.

Title

Purification, properties and function of a unique gamma-glutamyl cyclotransferase from the housefly, Musca domestica L.

Journal

Biochim Biophys Acta 315:352-362 (1973)

Reference

2 [PMID:5781001]

Authors

Orlowski M, Richman PG, Meister A.

Title

Isolation and properties of gamma-L-glutamylcyclotransferase from human brain.

Journal

Biochemistry 8:1048-55 (1969)
DOI:10.1021/bi00831a036

Reference

3 [PMID:18515354]

Authors

Oakley AJ, Yamada T, Liu D, Coggan M, Clark AG, Board PG

Title

The identification and structural characterization of C7orf24 as gamma-glutamyl cyclotransferase. An essential enzyme in the gamma-glutamyl cycle.

Journal

J Biol Chem 283:22031-42 (2008)
DOI:10.1074/jbc.M803623200

Sequence

[hsa:79017]

Reference

4 [PMID:24214398]

Authors

Paulose B, Chhikara S, Coomey J, Jung HI, Vatamaniuk O, Dhankher OP

Title

A gamma-glutamyl cyclotransferase protects Arabidopsis plants from heavy metal toxicity by recycling glutamate to maintain glutathione homeostasis.

Journal

Plant Cell 25:4580-95 (2013)
DOI:10.1105/tpc.113.111815

Sequence

[ath:AT5G26220]

Other DBs

ExplorEnz - The Enzyme Database:

4.3.2.9

IUBMB Enzyme Nomenclature:

4.3.2.9

ExPASy - ENZYME nomenclature database:

4.3.2.9

BRENDA, the Enzyme Database:

4.3.2.9

CAS:

9045-44-7

DBGET integrated database retrieval system