| Entry |
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| Name |
tirucalladienol synthase;
PEN3
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| Class |
Isomerases;
Intramolecular transferases;
Transferring other groups
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| Sysname |
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, tirucalla-7,24-dien-3beta-ol-forming)
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| Reaction(IUBMB) |
(3S)-2,3-epoxy-2,3-dihydrosqualene = tirucalla-7,24-dien-3beta-ol [RN: R09916]
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| Reaction(KEGG) |
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| Substrate |
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD: C01054]
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| Product |
tirucalla-7,24-dien-3beta-ol [CPD: C20195]
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| Comment |
The product from Arabidopsis thaliana is 85% tirucalla-7,24-dien-3beta-ol with trace amounts of other triterpenoids.
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| History |
EC 5.4.99.56 created 2011
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| Pathway |
| ec00909 | Sesquiterpenoid and triterpenoid biosynthesis |
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| Orthology |
| K16205 | tirucalladienol synthase |
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| Genes |
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| Reference |
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| Authors |
Morlacchi P, Wilson WK, Xiong Q, Bhaduri A, Sttivend D, Kolesnikova MD, Matsuda SP |
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| Title |
Product profile of PEN3: the last unexamined oxidosqualene cyclase in Arabidopsis thaliana. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 5.4.99.56 |
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