Entry
Name
2-hydroxychromene-2-carboxylate isomerase;
HCCA isomerase;
2HC2CA isomerase;
2-hydroxychromene-2-carboxylic acid isomerase
Class
Isomerases;
Other isomerases;
Sole sub-subclass for isomerases that do not belong in the other subclasses
BRITE hierarchy
Sysname
2-hydroxy-2H-chromene-2-carboxylate---(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate isomerase
Reaction(IUBMB)
2-hydroxy-2H-chromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate [RN:
R05137 ]
Reaction(KEGG)
Substrate
2-hydroxy-2H-chromene-2-carboxylate [CPD:
C06204 ]
Product
(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate [CPD:
C06203 ]
Comment
This enzyme is involved in naphthalene degradation.
History
EC 5.99.1.4 created 2010
Pathway
ec01120 Microbial metabolism in diverse environments
Orthology
K14584 2-hydroxychromene-2-carboxylate isomerase
Genes
BUQ : AC233_10855 AC233_11015 AC233_11145
PGV : SL003B_4081 SL003B_4106
NPP : PP1Y_AT15569 PP1Y_AT31717
NPN : JI59_21735 JI59_21885 JI59_24555
CNA : AB433_10405 AB433_18205
» show all
Taxonomy
Reference
Authors
Ohmoto T, Kinoshita T, Moriyoshi K, Sakai K, Hamada N, Ohe T
Title
Purification and some properties of 2-hydroxychromene-2-carboxylate isomerase from naphthalenesulfonate-assimilating Pseudomonas sp. TA-2.
Journal
Reference
Authors
Keck A, Conradt D, Mahler A, Stolz A, Mattes R, Klein J
Title
Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6.
Journal
Sequence
Reference
Authors
Eaton RW
Title
Organization and evolution of naphthalene catabolic pathways: sequence of the DNA encoding 2-hydroxychromene-2-carboxylate isomerase and trans-o-hydroxybenzylidenepyruvate hydratase-aldolase from the NAH7 plasmid.
Journal
Sequence
Reference
Authors
Thompson LC, Ladner JE, Codreanu SG, Harp J, Gilliland GL, Armstrong RN
Title
2-Hydroxychromene-2-carboxylic acid isomerase: a kappa class glutathione transferase from Pseudomonas putida.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.99.1.4
ExPASy - ENZYME nomenclature database: 5.99.1.4
UM-BBD (Biocatalysis/Biodegradation Database): 5.99.1.4