KEGG   Heterocephalus glaber (naked mole-rat): 101697126
Entry
101697126         CDS       T02812                                 
Symbol
Traf6
Name
(RefSeq) TNF receptor associated factor 6
  KO
K03175  TNF receptor-associated factor 6 [EC:2.3.2.27]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04010  MAPK signaling pathway
hgl04064  NF-kappa B signaling pathway
hgl04120  Ubiquitin mediated proteolysis
hgl04140  Autophagy - animal
hgl04144  Endocytosis
hgl04380  Osteoclast differentiation
hgl04620  Toll-like receptor signaling pathway
hgl04621  NOD-like receptor signaling pathway
hgl04622  RIG-I-like receptor signaling pathway
hgl04657  IL-17 signaling pathway
hgl04722  Neurotrophin signaling pathway
hgl04936  Alcoholic liver disease
hgl05132  Salmonella infection
hgl05133  Pertussis
hgl05135  Yersinia infection
hgl05140  Leishmaniasis
hgl05142  Chagas disease
hgl05145  Toxoplasmosis
hgl05152  Tuberculosis
hgl05160  Hepatitis C
hgl05161  Hepatitis B
hgl05162  Measles
hgl05168  Herpes simplex virus 1 infection
hgl05169  Epstein-Barr virus infection
hgl05170  Human immunodeficiency virus 1 infection
hgl05171  Coronavirus disease - COVID-19
hgl05200  Pathways in cancer
hgl05222  Small cell lung cancer
hgl05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hgl05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    101697126 (Traf6)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101697126 (Traf6)
   04064 NF-kappa B signaling pathway
    101697126 (Traf6)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    101697126 (Traf6)
   04140 Autophagy - animal
    101697126 (Traf6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101697126 (Traf6)
   04621 NOD-like receptor signaling pathway
    101697126 (Traf6)
   04622 RIG-I-like receptor signaling pathway
    101697126 (Traf6)
   04657 IL-17 signaling pathway
    101697126 (Traf6)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    101697126 (Traf6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101697126 (Traf6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101697126 (Traf6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101697126 (Traf6)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    101697126 (Traf6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101697126 (Traf6)
   05161 Hepatitis B
    101697126 (Traf6)
   05160 Hepatitis C
    101697126 (Traf6)
   05171 Coronavirus disease - COVID-19
    101697126 (Traf6)
   05162 Measles
    101697126 (Traf6)
   05168 Herpes simplex virus 1 infection
    101697126 (Traf6)
   05169 Epstein-Barr virus infection
    101697126 (Traf6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101697126 (Traf6)
   05135 Yersinia infection
    101697126 (Traf6)
   05133 Pertussis
    101697126 (Traf6)
   05152 Tuberculosis
    101697126 (Traf6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101697126 (Traf6)
   05140 Leishmaniasis
    101697126 (Traf6)
   05142 Chagas disease
    101697126 (Traf6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101697126 (Traf6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101697126 (Traf6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hgl04131]
    101697126 (Traf6)
   04121 Ubiquitin system [BR:hgl04121]
    101697126 (Traf6)
Enzymes [BR:hgl01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     101697126 (Traf6)
Membrane trafficking [BR:hgl04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    101697126 (Traf6)
Ubiquitin system [BR:hgl04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRAF proteins
    101697126 (Traf6)
SSDB
Motif
Pfam: TRAF-mep_MATH zf-TRAF TRAF6_Z2 zf-C3HC4_2 zf-C3HC4 zf-RING_UBOX zf-RING_2 zf-C3HC4_3 zf-C3HC4_4 zf-RING_5 zf-TRAF_2 TRAF3_RING U-box zf-RING_11 SlyX DUF16 DUF4455 PspA_IM30 DUF3450 Spc29
Other DBs
NCBI-GeneID: 101697126
NCBI-ProteinID: XP_004852082
UniProt: G5B132
Position
Un
AA seq 543 aa
MSLINCENSCGSSQSESDCCAAMASSCSTAAKDDSVSGVPSTSTGNLSSSFMEEIQGYDV
EFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLF
PDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQVLCEFALVNCSQCQRPFQKCQLNIHI
LTDCPRRQVSCVNCAVSMPFEEKEIHDQNCPLANVICEYCHTMLIREQMPTHYDLDCPTA
PIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLNLALTPVPPRDLLPYDAA
SLPRVSSGCHPEVQNFQETIQQLEGRLVRQDHQIRELTAKMETQCMYVNELKGTIRTLED
KVAEIEAQQCNGIYIWKIGNFGMHLKSQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPT
AQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAF
QRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDMGGLRKEGFQPRSTD
AGV
NT seq 1632 nt   +upstreamnt  +downstreamnt
atgagtctgataaactgtgaaaacagctgtggatccagccagtctgaaagcgactgctgt
gctgccatggccagctcctgtagcactgcagcgaaagacgacagtgtgagcggggtgccc
agcaccagcacggggaacctgtccagctccttcatggaggagatccagggatatgatgta
gagtttgacccgcccctggaaagcaagtacgagtgccccatctgcttgatggctctgcgg
gaagcagtgcagacgccgtgtggccatcggttctgcaaggcctgcatcatcaaatcaata
agggatgcaggtcacaaatgtccagttgacaacgaaatactgctggaaaatcaactattt
cctgataattttgcaaaacgagagattctctctctgatggtaaagtgtccaaatgaaggt
tgtttgcacaagatggaattgaggcatcttgaggaccatcaagtactctgtgagtttgct
cttgtgaattgttcccaatgccagcgcccctttcaaaaatgccagttgaatattcatatc
ctcacggattgtccaaggagacaggtttcttgtgtaaactgtgctgtatccatgcctttt
gaggaaaaggagatccatgaccagaactgtcctttggcaaatgtcatctgtgaatattgc
cacaccatgctcatcagagaacagatgcctactcattatgatctagactgtcctacagcc
ccgatcccctgcaccttcagtacttttggttgccatgaaaagatgcagagaaatcacttg
gcacgccacctgcaagagaatacccagtcgcacatgagaatgttggctcaggctgttcat
agtttaaaccttgctttaactcctgtgcctccacgtgacctgcttccatacgatgctgcc
tctctgccccgggtttcctctgggtgccacccagaggtccagaatttccaggaaaccatt
caacagttagagggtcgccttgtaagacaggaccatcaaatccgggagctgactgcgaaa
atggaaactcagtgtatgtatgtaaatgagcttaaaggaactattcgaaccctcgaggac
aaagtcgctgaaattgaagcacagcagtgcaatgggatttacatttggaaaattggcaac
tttggcatgcacttaaagtctcaagaagaggagaagcctgttgtcattcatagccctgga
ttctacacaggcaaacccgggtacaaactgtgcatgcgcctgcaccttcagttaccaact
gctcagcgctgtgcaaactatatatccctctttgtccacacaatgcaaggagagtatgac
agccacctcccttggcccttccagggtacaatacgccttacaattcttgatcagtctgaa
gccccagtaaggcaaaaccacgaagagataatggatgccaaaccagagctgcttgccttc
cagcggcccacaatcccacggaatccaaaaggttttggctatgtaactttcatgcacttg
gaagccctaagacaaagaaccttcattaaggatgatacgttgttagtgcgctgtgaagtt
tctacccgcttcgacatgggtggccttcgcaaggagggttttcagccacggagtactgat
gcaggggtatag

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (30)   
   KEGG PATHWAY (30)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (6)   
   RefSeq(nuc) (4)   
   GenBank (1)   
   EMBL (1)   
Protein domain (20)   
   Pfam (20)   
All databases (80)   

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