KEGG   Heterocephalus glaber (naked mole-rat): 101709178
Entry
101709178         CDS       T02812                                 
Symbol
Rab8a
Name
(RefSeq) RAB8A, member RAS oncogene family
  KO
K07901  Ras-related protein Rab-8A
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04140  Autophagy - animal
hgl04144  Endocytosis
hgl04152  AMPK signaling pathway
hgl04530  Tight junction
hgl04972  Pancreatic secretion
hgl05014  Amyotrophic lateral sclerosis
hgl05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    101709178 (Rab8a)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    101709178 (Rab8a)
   04140 Autophagy - animal
    101709178 (Rab8a)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    101709178 (Rab8a)
 09150 Organismal Systems
  09154 Digestive system
   04972 Pancreatic secretion
    101709178 (Rab8a)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101709178 (Rab8a)
   05022 Pathways of neurodegeneration - multiple diseases
    101709178 (Rab8a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hgl04131]
    101709178 (Rab8a)
   03036 Chromosome and associated proteins [BR:hgl03036]
    101709178 (Rab8a)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hgl04147]
    101709178 (Rab8a)
   04031 GTP-binding proteins [BR:hgl04031]
    101709178 (Rab8a)
Membrane trafficking [BR:hgl04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab GTPases
    101709178 (Rab8a)
 Autophagy
  Other autophagy associated proteins
    101709178 (Rab8a)
Chromosome and associated proteins [BR:hgl03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centriole associated proteins
    101709178 (Rab8a)
Exosome [BR:hgl04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101709178 (Rab8a)
  Exosomal proteins of other body fluids (saliva and urine)
   101709178 (Rab8a)
  Exosomal proteins of colorectal cancer cells
   101709178 (Rab8a)
GTP-binding proteins [BR:hgl04031]
 Small (monomeric) G-proteins
  Rab Family
   Rab8/10/13 [OT]
    101709178 (Rab8a)
SSDB
Motif
Pfam: Ras Roc Arf Gtr1_RagA GTP_EFTU MMR_HSR1 SRPRB DUF3963 Septin AAA_7
Other DBs
NCBI-GeneID: 101709178
NCBI-ProteinID: XP_004873362
UniProt: G5C2V3
Position
Un
AA seq 207 aa
MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQ
IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILG
NKCDVNDKRQVSRERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGN
SPQGSSQGMKITPDQQKRSSFFRCMLL
NT seq 624 nt   +upstreamnt  +downstreamnt
atggcgaagacctacgattacctgttcaagctgctgctcatcggggactcgggggtgggg
aagacctgtgtcctgttccgcttctccgaggacgccttcaactccactttcatctccacc
ataggaatcgactttaaaattaggaccatagagctcgatggcaagaggatcaaactccag
atttgggacacagccgggcaagaacggtttcggacgatcacgacggcctactacaggggc
gccatgggcatcatgctggtctacgacatcaccaatgagaagtcctttgacaacatccgg
aactggatccggaacatcgaggagcacgcctcggccgacgtggagaagatgatcctgggg
aacaagtgcgatgtgaacgacaagagacaagtgtccagggagcggggagagaagctggcg
ctcgactatgggatcaagttcatggagaccagtgccaaggccaacatcaacgtggagaat
gcgtttttcactctcgccagagacatcaaggcaaaaatggacaaaaaattggaaggcaac
agcccgcagggaagcagccagggaatgaagatcacgccggaccagcagaagcggagcagc
ttcttccgctgcatgctcctgtga

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