KEGG   Heterocephalus glaber (naked mole-rat): 101712811
Entry
101712811         CDS       T02812                                 
Symbol
Pak3
Name
(RefSeq) p21 (RAC1) activated kinase 3
  KO
K05733  p21-activated kinase 3 [EC:2.7.11.1]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl04012  ErbB signaling pathway
hgl04014  Ras signaling pathway
hgl04360  Axon guidance
hgl04510  Focal adhesion
hgl04660  T cell receptor signaling pathway
hgl04810  Regulation of actin cytoskeleton
hgl05132  Salmonella infection
hgl05170  Human immunodeficiency virus 1 infection
hgl05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    101712811 (Pak3)
   04014 Ras signaling pathway
    101712811 (Pak3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101712811 (Pak3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101712811 (Pak3)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    101712811 (Pak3)
  09158 Development and regeneration
   04360 Axon guidance
    101712811 (Pak3)
 09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    101712811 (Pak3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101712811 (Pak3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101712811 (Pak3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hgl01001]
    101712811 (Pak3)
Enzymes [BR:hgl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     101712811 (Pak3)
Protein kinases [BR:hgl01001]
 Serine/threonine kinases: STE group
  STE20 family
   101712811 (Pak3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT Kdo
Other DBs
NCBI-GeneID: 101712811
NCBI-ProteinID: XP_004861488
UniProt: A0A0P6JWY8
Position
Un
AA seq 559 aa
MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN
KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTS
NITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPP
LAPPVSEEEDEEEEEEEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEVTPPSA
ENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTA
LDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYL
AGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTD
FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNE
NPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPL
SSLTPLIIAAKEAIKNSSR
NT seq 1680 nt   +upstreamnt  +downstreamnt
atgtctgacggtctggataatgaagaaaaacccccagctcctccactgaggatgaatagt
aacaaccgggattcttcagcactcaaccacagctccaaaccacttcccatggcccctgaa
gagaagaataagaaagccaggcttcgctccatcttcccaggaggaggggataaaaccaat
aagaagaaagagaaagaacgcccagagatctctcttccttcagactttgagcatacgatt
catgtggggtttgatgcagtcaccggggaattcactccagatctctatggctcacagatg
tgcccagggaagctcccagagggaattcctgaacaatgggcacgattactccaaacctcc
aacataacaaaactggaacagaagaagaacccacaagctgttttagatgttctcaaattc
tatgattccaaagaaacagtcaacaaccagaaatacatgagctttacatcaggagataaa
agcgcccatggatatatagcagcacatccttcaagtacaaaaacagcatctgagcctcct
ttagctcctccggtatctgaagaagaagacgaagaagaggaggaggaagaagatgacaat
gagcccccacctgttattgcaccaagaccagagcatacaaaatcaatctatactcgttct
gtggttgaatccattgcttcaccagcagcaccaaataaagaagtcacaccaccttctgct
gagaatgccaattccagtactttgtacagaaatacagatcgccaaaggaagaaatccaag
atgacagatgaggagatcctagagaagctaagaagcattgtaagtgttggggacccaaag
aaaaagtacacacgatttgaaaaaattggtcaaggggcatcaggtactgtttatacagca
ctagatattgcaacaggacaagaggtggccataaagcagatgaaccttcaacagcaaccc
aaaaaggaattaattattaatgaaattctggtcatgagggaaaataagaaccccaatatt
gttaattatttggatagctacttagtgggtgatgaactgtgggtagtcatggaatacttg
gccggtggctctttgactgatgtggtcacagagacctgtatggatgaaggacagatagca
gctgtctgcagagagtgcctccaagctctggatttcttgcactcaaaccaagtgatccat
agagacatcaaaagtgacaatattctccttgggatggatggctctgttaaattgactgat
tttgggttctgtgcccagatcactccagagcaaagtaagcgaagcactatggtgggcacc
ccctattggatggcacctgaggtggtgactcgaaaagcttatggtccgaaagttgatatc
tggtctctgggaattatggcaattgaaatggtggaaggtgaacccccttaccttaatgaa
aatccactcagggcattatacctgatagccactaatggaaccccagagctccagaatcct
gagaggctgtcagctgtattccgtgactttttaaatcgctgtcttgagatggatgtggat
aggcgaggatctgccaaggagcttttgcagcatccatttttaaaactagccaagcctctc
tccagcctgactcctctgattatcgctgcaaaagaagcgattaagaacagcagccgctag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   RefSeq(pep) (7)   
DNA sequence (9)   
   RefSeq(nuc) (7)   
   GenBank (1)   
   EMBL (1)   
Protein domain (9)   
   Pfam (9)   
All databases (49)   

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