KEGG   Homo sapiens (human): 10010
Entry
10010             CDS       T01001                                 
Symbol
TANK, I-TRAF, ITRAF, TRAF2
Name
(RefSeq) TRAF family member associated NFKB activator
  KO
K12650  TRAF family member-associated NF-kappa-B activator
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa04621  NOD-like receptor signaling pathway
hsa04622  RIG-I-like receptor signaling pathway
hsa05014  Amyotrophic lateral sclerosis
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05417  Lipid and atherosclerosis
Network
nt06162  Hepatitis B virus (HBV)
nt06163  Hepatitis C virus (HCV)
nt06165  Epstein-Barr virus (EBV)
nt06168  Herpes simplex virus 1 (HSV-1)
nt06169  Measles virus (MV)
nt06170  Influenza A virus (IAV)
nt06171  SARS coronavirus 2 (SARS-CoV-2)
nt06263  Hepatocellular carcinoma
nt06519  RLR signaling
  Element
N00469  RIG-I-IRF7/3 signaling pathway
N01308  MDA5-IRF7/3 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    10010 (TANK)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    10010 (TANK)
   04622 RIG-I-like receptor signaling pathway
    10010 (TANK)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    10010 (TANK)
   05022 Pathways of neurodegeneration - multiple diseases
    10010 (TANK)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    10010 (TANK)
SSDB
Motif
Pfam: TBD PspA_IM30 FliD_N MYRF_ICA
Other DBs
NCBI-GeneID: 10010
NCBI-ProteinID: NP_001186064
OMIM: 603893
HGNC: 11562
Ensembl: ENSG00000136560
UniProt: Q92844 B2R7S3 Q6NW12
Structure
Position
2:161136963..161236230
AA seq 425 aa
MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKS
QLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRK
ETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVP
IQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMD
NDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAI
QNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGK
AIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSH
FNGET
NT seq 1278 nt   +upstreamnt  +downstreamnt
atggataaaaacattggcgagcaactcaataaagcgtatgaagccttccggcaggcatgc
atggatagagattctgcagtaaaagaattacagcaaaagactgagaactatgagcagaga
atacgtgaacaacaggaacagctgtcacttcaacagactattattgacaagctaaaatct
cagttacttcttgtgaattccactcaagataacaattatggctgtgttcctctgcttgaa
gacagtgaaacaagaaagaataatttgactcttgatcagccacaagataaagtgatttca
ggaatagcaagagaaaaactaccaaaggtaagaagacaagaggtttcttctcctagaaaa
gaaacttcagcaaggagtcttggcagtcctttgctccatgaaaggggtaatatagagaag
actttctgggatctgaaagaagaatttcataaaatatgcatgctagcaaaagcacagaaa
gaccacttaagcaaacttaatataccagacactgcaactgaaacacagtgctctgtgcct
atacagtgtacggataaaacagataaacaagaagcgctgtttaagcctcaggctaaagat
gatataaatagaggtgcaccatccatcacatctgtcacaccaagaggactgtgcagagat
gaggaagacacctcttttgaatcactttctaaattcaatgtcaagtttccacctatggac
aatgactcaactttcttacatagcactccagagagacccggcatccttagtcctgccacg
tctgaggcagtgtgccaagagaaatttaatatggagttcagagacaacccagggaacttt
gttaaaacagaagaaactttatttgaaattcagggaattgaccccatagcttcagctata
caaaaccttaaaacaactgacaaaacaaagccctcaaatctcgtaaacacttgtatcagg
acaactctggatagagctgcgtgtttgccacctggagaccataatgcattatatgtaaat
agcttcccacttctggacccatctgatgcaccttttccctcactcgattccccgggaaaa
gcaatccgaggaccacagcagcccatttggaagccctttcctaatcaagacagtgactcg
gtggtactaagtggcacagactcagaactgcatatacctcgagtatgtgaattctgtcaa
gcagttttcccaccatccattacatccaggggggatttccttcggcatcttaattcacac
ttcaatggagagacttaa

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Network (11)   
   KEGG NETWORK (11)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (28)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (36)   
   RefSeq(nuc) (24)   
   GenBank (6)   
   EMBL (6)   
3D Structure (3)   
   PDB (3)   
Protein domain (4)   
   Pfam (4)   
All databases (108)   

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