KEGG   Homo sapiens (human): 10531
Entry
10531             CDS       T01001                                 
Symbol
PITRM1, MP1, PreP, SCAR30
Name
(RefSeq) pitrilysin metallopeptidase 1
  KO
K06972  presequence protease [EC:3.4.24.-]
Organism
hsa  Homo sapiens (human)
Disease
H01891  Autosomal recessive spinocerebellar ataxias
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    10531 (PITRM1)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M16: pitrilysin family
   10531 (PITRM1)
SSDB
Motif
Pfam: M16C_assoc Peptidase_M16_C Peptidase_M16
Other DBs
NCBI-GeneID: 10531
NCBI-ProteinID: NP_055704
OMIM: 618211
HGNC: 17663
Ensembl: ENSG00000107959
UniProt: Q5JRX3
Structure
Position
10:complement(3137727..3172841)
AA seq 1037 aa
MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPEL
FLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCR
DPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQE
GWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPL
CIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQ
TPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSP
FYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGF
EDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQE
NPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEK
GLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRA
FSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMD
TYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHL
YASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRC
SVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIR
KLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIR
EKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVF
STVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAI
LGPENPKIAKDPSWIIQ
NT seq 3114 nt   +upstreamnt  +downstreamnt
atgtggcgctgcggcgggcggcagggcctgtgtgtgctgaggcggctgagcggcggacat
gcacaccacagagcgtggcgatggaacagtaaccgggcttgtgagagggctctgcagtat
aaactaggagacaagatccatggattcaccgtaaaccaggtgacatctgttcccgagctg
ttcctgactgcagtgaagctcacccatgatgacacaggagccaggtatttacacctggcc
agagaagacacgaataatctgttcagcgtgcagttccgtactactcccatggacagtact
ggtgttcctcacattcttgagcataccgtcctttgtgggtctcagaaatatccgtgcaga
gaccctttcttcaaaatgttgaaccggtccctctccacgttcatgaacgccttcacagct
agtgattatactctgtatccattttccacacaaaatcccaaggactttcagaatctcctc
tcggtgtatttggatgccacctttttcccatgtttacgcgagctggatttctggcaggaa
ggatggcggctggaacatgagaatccgagcgacccccagacgcccttggtctttaaagga
gtcgtctttaatgagatgaagggagcgtttacagacaatgagaggatattctcccagcac
cttcagaacagacttcttcctgaccacacgtactcagtggtctccgggggtgacccactg
tgcatcccggagcttacatgggagcagcttaagcagtttcatgccactcactatcaccca
agcaatgctaggttcttcacgtacggtaattttccattagaacagcatctgaaacaaatt
cacgaggaagcactgagcaaattccagaaaattgaaccaagcaccgtggtgccagctcag
acaccctgggacaagcctagggaattccagataacatgtggcccggattcatttgctaca
gatccctctaaacaaacaaccatcagcgttagcttcctcttaccggacatcaccgacaca
tttgaagccttcacattaagtcttctgtcttcactcttgacttctgggcccaattctccc
ttttacaaagccttgattgaatctggccttggcacagacttttctcctgatgttggatat
aatggctacacgagggaggcctactttagtgtcggcctccaagggattgcggagaaagac
attgagaccgtcagaagcctcatagacagaacgattgatgaagtagttgagaaaggattt
gaagatgatcgaattgaggctttacttcataaaattgaaatacagatgaaacatcagtct
accagctttgggctgatgctgacatcatacatagcttcttgctggaaccatgatggggac
cctgtggagctcttgaagttgggaaatcagttagctaaattcagacagtgcctgcaggaa
aatccaaaatttttgcaagaaaaagtaaaacagtattttaagaataaccagcataagctg
actttatcgatgaggccagatgacaagtatcacgagaagcaggcacaggtggaagccacg
aagctcaagcagaaggtcgaggctctgtcccccggagacaggcagcagatctacgagaaa
ggtctagaattacggagtcaacaaagcaaacctcaagatgcctcttgtctgccagcgttg
aaagtttccgatattgaacccaccatacctgtcacagagttggacgtggtcctgacagct
ggagatatccctgttcagtactgcgcccagcccaccaatggcatggtgtatttccgggcc
ttctccagcctgaacacactccccgaggagctgaggccctatgtgcccctcttctgcagc
gtcctcaccaagctgggctgcggccttcttgactaccgggagcaggctcagcagatagaa
ttgaagaccggagggatgagtgcttctccccacgtgctccccgacgactcacacatggac
acctacgagcagggtgtgcttttctcctctctctgcctggatcgaaacctgccagacatg
atgcagctatggagtgaaatatttaacaacccgtgctttgaagaagaggagcacttcaag
gtgctggtgaagatgaccgcccaggagctcgccaatggaattcctgactctgggcacctg
tacgcatccatcagggcaggccggaccctcacgcccgcaggggacctgcaggagaccttc
agcgggatggatcaggtgcggctgatgaagaggattgcagaaatgacagatatcaaaccc
atcctgaggaagctcccgcgtatcaagaaacacttgttaaatggtgataatatgaggtgt
tcagtgaatgcgactcctcagcagatgcctcagacagaaaaagcggtcgaagacttcctt
agaagcatcggtcggagtaaaaaggaacggaggcctgtgcgcccacacacggtcgagaaa
cctgtgcccagcagctctggtggagatgcccacgttccccatggctcccaggtcattagg
aagctggtcatggaacccaccttcaagccctggcagatgaagactcacttcctgatgccc
ttcccggtgaattacgtgggtgaatgcatccgaactgtcccctacacggacccagatcat
gccagtcttaaaatccttgcacgtttgatgactgccaaattcttgcatacagaaattcga
gaaaaaggcggtgcttatggtggaggcgcaaaactcagccacaatgggattttcaccctt
tactcttacagggacccaaatacaatagagacgctccagtcttttgggaaggctgtcgac
tgggctaagtctggaaaattcacacagcaagacatcgacgaagccaaactttctgtcttc
tcaaccgtagatgctcctgtcgctccttcagacaaaggaatggaccacttcttgtacggc
ctctcggatgagatgaagcaggcccacagagagcagctctttgctgtcagccacgacaag
ctcctggccgtgagcgatagatacctcggcactgggaagagcacacacggcctggccatc
ctcggacccgagaacccgaaaattgccaaggacccatcctggatcatccaatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (15)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (72)   
   RefSeq(nuc) (18)   
   GenBank (27)   
   EMBL (27)   
3D Structure (8)   
   PDB (8)   
Protein domain (3)   
   Pfam (3)   
All databases (123)   

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