KEGG   Homo sapiens (human): 10768
Entry
10768             CDS       T01001                                 
Symbol
AHCYL1, DCAL, IRBIT, PPP1R78, PRO0233, XPVKONA
Name
(RefSeq) adenosylhomocysteinase like 1
  KO
K01251  adenosylhomocysteinase [EC:3.13.2.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00270  Cysteine and methionine metabolism
hsa01100  Metabolic pathways
Module
hsa_M00035  Methionine degradation
Network
nt06030  Methionine metabolism
  Element
N01607  Methionine degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    10768 (AHCYL1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    10768 (AHCYL1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    10768 (AHCYL1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.13  Acting on carbon-sulfur bonds
   3.13.2  Thioether and trialkylsulfonium hydrolases
    3.13.2.1  adenosylhomocysteinase
     10768 (AHCYL1)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     10768 (AHCYL1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   10768 (AHCYL1)
SSDB
Motif
Pfam: AdoHcyase AdoHcyase_NAD 2-Hacid_dh_C IlvN THF_DHG_CYH_C NAD_binding_7 Shikimate_DH AlaDh_PNT_C TrkA_N Big_3_5 Glu_dehyd_C Utp11 SR-25
Other DBs
NCBI-GeneID: 10768
NCBI-ProteinID: NP_006612
OMIM: 607826
HGNC: 344
Ensembl: ENSG00000168710
UniProt: O43865 A0A024R0A8
Structure
Position
1:109984765..110023742
AA seq 530 aa
MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
NT seq 1593 nt   +upstreamnt  +downstreamnt
atgtcgatgcctgacgcgatgccgctgcccggggtcggggaggagctgaagcaggccaag
gagatcgaggacgccgagaagtactccttcatggccaccgtcaccaaggcgcccaagaag
caaatccagtttgctgatgacatgcaggagttcaccaaattccccaccaaaactggccga
agatctttgtctcgctcgatctcacagtcctccactgacagctacagttcagctgcatcc
tacacagatagctctgatgatgaggtttctccccgagagaagcagcaaaccaactccaag
ggcagcagcaatttctgtgtgaagaacatcaagcaggcagaatttggacgccgggagatt
gagattgcagagcaagacatgtctgctctgatttcactcaggaaacgtgctcagggggag
aagcccttggctggtgctaaaatagtgggctgtacacacatcacagcccagacagcggtg
ttgattgagacactctgtgccctgggggctcagtgccgctggtctgcttgtaacatctac
tcaactcagaatgaagtagctgcagcactggctgaggctggagttgcagtgttcgcttgg
aagggcgagtcagaagatgacttctggtggtgtattgaccgctgtgtgaacatggatggg
tggcaggccaacatgatcctggatgatgggggagacttaacccactgggtttataagaag
tatccaaacgtgtttaagaagatccgaggcattgtggaagagagcgtgactggtgttcac
aggctgtatcagctctccaaagctgggaagctctgtgttccggccatgaacgtcaatgat
tctgttaccaaacagaagtttgataacttgtactgctgccgagaatccattttggatggc
ctgaagaggaccacagatgtgatgtttggtgggaaacaagtggtggtgtgtggctatggt
gaggtaggcaagggctgctgtgctgctctcaaagctcttggagcaattgtctacattacc
gaaatcgaccccatctgtgctctgcaggcctgcatggatgggttcagggtggtaaagcta
aatgaagtcatccggcaagtcgatgtcgtaataacttgcacaggaaataagaatgtagtg
acacgggagcacttggatcgcatgaaaaacagttgtatcgtatgcaatatgggccactcc
aacacagaaatcgatgtgaccagcctccgcactccggagctgacgtgggagcgagtacgt
tctcaggtggaccatgtcatctggccagatggcaaacgagttgtcctcctggcagagggt
cgtctactcaatttgagctgctccacagttcccacctttgttctgtccatcacagccaca
acacaggctttggcactgatagaactctataatgcacccgaggggcgatacaagcaggat
gtgtacttgcttcctaagaaaatggatgaatacgttgccagcttgcatctgccatcattt
gatgcccaccttacagagctgacagatgaccaagcaaaatatctgggactcaacaaaaat
gggccattcaaacctaattattacagatactaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (12)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (63)   
   RefSeq(nuc) (9)   
   GenBank (27)   
   EMBL (27)   
3D Structure (1)   
   PDB (1)   
Protein domain (13)   
   Pfam (13)   
All databases (126)   

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