KEGG   Homo sapiens (human): 116986
Entry
116986            CDS       T01001                                 
Symbol
AGAP2, CENTG1, GGAP2, PIKE
Name
(RefSeq) ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
  KO
K17848  Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04068  FoxO signaling pathway
hsa04144  Endocytosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    116986 (AGAP2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    116986 (AGAP2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    116986 (AGAP2)
Membrane trafficking [BR:hsa04131]
 Endosome - Golgi transport
  Arf GTPases and associated proteins
   Arf GTPase associated proteins
    116986 (AGAP2)
SSDB
Motif
Pfam: ArfGap Ras PH Ank_2 Ank Ank_4 Ank_5 PH_6 Roc Ank_3 SpoIVA_ATPase MLVIN_C
Other DBs
NCBI-GeneID: 116986
NCBI-ProteinID: NP_001116244
OMIM: 605476
HGNC: 16921
Ensembl: ENSG00000135439
UniProt: Q99490 F8VVT9
Structure
Position
12:complement(57723761..57742161)
AA seq 1192 aa
MSRGAGALQRRTTTYLISLTLVKLESVPPPPPSPSAAAAGAAGARGSETGDPGSPRGAEE
PGKKRHERLFHRQDALWISTSSAGTGGAEPPALSPAPASPARPVSPAPGRRLSLWAVPPG
PPLSGGLSPDPKPGGAPTSSRRPLLSSPSWGGPEPEGRAGGGIPGSSSPHPGTGSRRLKV
APPPPAPKPCKTVTTSGAKAGGGKGAGSRLSWPESEGKPRVKGSKSSAGTGASVSAAATA
AAAGGGGSTASTSGGVGAGAGARGKLSPRKGKSKTLDNSDLHPGPPAGSPPPLTLPPTPS
PATAVTAASAQPPGPAPPITLEPPAPGLKRGREGGRASTRDRKMLKFISGIFTKSTGGPP
GSGPLPGPPSLSSGSGSRELLGAELRASPKAVINSQEWTLSRSIPELRLGVLGDARSGKS
SLIHRFLTGSYQVLEKTESEQYKKEMLVDGQTHLVLIREEAGAPDAKFSGWADAVIFVFS
LEDENSFQAVSRLHGQLSSLRGEGRGGLALALVGTQDRISASSPRVVGDARARALCADMK
RCSYYETCATYGLNVDRVFQEVAQKVVTLRKQQQLLAACKSLPSSPSHSAASTPVAGQAS
NGGHTSDYSSSLPSSPNVGHRELRAEAAAVAGLSTPGSLHRAAKRRTSLFANRRGSDSEK
RSLDSRGETTGSGRAIPIKQSFLLKRSGNSLNKEWKKKYVTLSSNGFLLYHPSINDYIHS
THGKEMDLLRTTVKVPGKRPPRAISAFGPSASINGLVKDMSTVQMGEGLEATTPMPSPSP
SPSSLQPPPDQTSKHLLKPDRNLARALSTDCTPSGDLSPLSREPPPSPMVKKQRRKKLTT
PSKTEGSAGQAEAKRKMWKLKSFGSLRNIYKAEENFEFLIVSSTGQTWHFEAASFEERDA
WVQAIESQILASLQCCESSKVKLRTDSQSEAVAIQAIRNAKGNSICVDCGAPNPTWASLN
LGALICIECSGIHRNLGTHLSRVRSLDLDDWPRELTLVLTAIGNDTANRVWESDTRGRAK
PSRDSSREERESWIRAKYEQLLFLAPLSTSEEPLGRQLWAAVQAQDVATVLLLLAHARHG
PLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYGADVAARDAQGRTALFYARQAGSQLCA
DILLQHGCPGEGGSAATTPSAATTPSITATPSPRRRSSAASVGRADAPVALV
NT seq 3579 nt   +upstreamnt  +downstreamnt
atgagccggggcgcgggcgcgcttcagcgccggacaacgacctacctcatctcgctgacc
ctggttaagctcgagtcggtgcctccgccgccgccttctccgtctgcggccgcggccggc
gccgccggtgccagaggctccgagactggggatcctggcagcccccgaggcgcggaggag
ccgggcaagaagcggcacgaacgtctcttccaccggcaggatgcgctgtggatcagcacg
agcagcgcgggcaccgggggcgcggagcccccagccctgtccccggctccggccagtccg
gcccgcccagtctcccccgctcccggccgccgcctctccctctgggccgtccctccggga
cccccgctctccgggggactgagccccgaccccaagcctgggggcgcccccacctcctcc
cggcgccccctgctcagcagcccgagctggggcggcccggagcccgaaggccgggcgggc
ggcggcatccctggctcatcctctccgcaccctggcaccggcagccggaggctcaaggtg
gcgcctcctccgccggctcccaagccttgcaagaccgtgaccacgagtggagccaaagcc
ggcgggggcaagggcgcgggtagccgcctgtcatggcccgaaagcgagggcaagcccagg
gtcaaggggtcaaagagcagcgccgggactggagcttcggtctctgccgccgccaccgcc
gccgccgccgggggagggggctctacagcttcgacctctggtggggtcggggctggggct
ggagcccgagggaagttgtcccctcggaaaggcaagagtaagaccttggacaacagtgac
ttgcatccgggaccgcctgccggctctcctcctccgctaaccctcccaccaactccgagt
ccagccactgctgtcaccgctgcttccgcgcagccccccgggcctgcacctccaatcact
ctggagcctccagctccggggctgaaacggggccgggaggggggccgagcatccactcgt
gaccgcaagatgctcaagtttatcagcggcatcttcaccaagagcacaggagggcctcct
ggctccgggccccttcccggaccccccagcctgtcttctggcagcgggtccagggagctg
ctgggcgccgagctccgcgcttcccctaaggctgtgatcaatagccaggaatggactttg
agccgctccattcctgaactgcgcctgggtgtgctgggcgatgccaggagtgggaagtca
tcgctcatccaccgattcctgactggctcataccaggtgctggagaagacagagagtgag
cagtacaagaaagaaatgttggtggatggacagacacatctggtgctaatccgagaggaa
gctggggcacctgatgccaagttctcaggctgggcagatgctgtgatcttcgtcttcagc
ctggaggatgagaacagtttccaggctgtgagccgtctccatgggcagctgagttccctt
cgcggggagggacgaggaggcctggccttggcactggtggggacacaagacaggatcagt
gcttcctcccctcgggtggtgggagatgctcgtgccagagctctgtgcgcggacatgaaa
cgctgcagctactatgagacttgtgcaacctatgggctcaatgtggatcgggtcttccag
gaggtggcccagaaggtggtgaccttgcgcaagcagcaacagcttctggctgcctgcaag
tccctgcccagctccccaagccactcagctgcatccactccggtagctggccaggctagt
aacgggggccacactagcgactactcttcttccctcccgtcctcaccgaatgttggtcac
cgggagctccgagccgaggcagctgcagtggctggattgagcaccccagggtccctgcac
cgggcagccaagcgcaggaccagcctttttgcgaatcgtcggggtagtgactccgagaaa
cgaagcttggatagtcggggagagacaacagggagtgggcgagccatccccatcaaacag
agcttcctactaaaacgaagtggcaattccttgaacaaagaatggaagaagaaatatgta
accctgtccagtaatggctttctactctaccaccccagtattaacgattacatccacagt
acccacggcaaggagatggacttgctgcgaacaacagtcaaagtcccgggcaagcggccc
ccgagggccatctctgcctttggcccctcagccagcattaacgggctcgtcaaggacatg
agcactgtccagatgggtgaaggcctggaagccactactcccatgccaagccctagcccc
agccccagttccctgcagccaccaccagatcagacatccaaacacctgctgaagccagac
cggaatttggcccgagccctcagcacggactgtaccccatctggagacctgagccccctg
agtcgggaaccccctccttctcccatggtgaagaagcagaggaggaaaaaattgacaaca
ccatccaagactgaaggctcggctgggcaggctgaagccaagcgcaaaatgtggaaacta
aaatcctttggtagtttaagaaatatttataaagcagaggaaaactttgagttcctgatc
gtgtccagcacgggtcagacgtggcactttgaggcagccagttttgaggagcgggatgcc
tgggtccaggccatcgagagtcagatcctagccagtctgcaatgctgtgagagcagcaag
gtcaagctgcgcacagacagccaaagcgaggccgtggccatccaggcgatccggaacgcc
aaggggaattcaatctgcgtggactgcggggcccccaaccccacgtgggccagcttgaac
ctgggcgccctcatctgcatcgagtgttctggcatccaccgcaacctgggcacacacctg
tcccgcgttcgctcgctggacttggacgactggccacgggagctgaccctggtgctgacg
gctattggcaacgacacggccaaccgcgtgtgggaaagcgacacgcgaggccgtgccaag
ccctcgcgggactcttcgcgggaggagcgcgagtcgtggattcgcgccaagtacgagcag
ctactgttcctggcgccgctgagcacctcggaggagccgctgggccgccagctgtgggcc
gccgtgcaggcccaggacgtggctaccgttctcctgcttttggcccatgcgcgacacggg
ccgctcgacaccagcgtagaggacccacagctgcgctccccactccacctggcggccgag
ctcgcccacgtcgtcatcacgcaactgctgctgtggtacggcgcggacgtggcggcccgt
gacgcccagggccgcacggcgctgttctacgcccgccaggctggaagccagctgtgcgcc
gacatccttctccagcacggctgcccgggtgagggcggcagcgcggccaccacgcccagc
gcggccaccacgcccagcatcaccgccacgcccagcccccgccgccggagcagcgccgct
agcgtgggccgcgccgacgccccggttgcgctggtatag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (60)   
   KEGG ORTHOLOGY (1)   
   RefGene (51)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (28)   
   RefSeq(nuc) (6)   
   GenBank (11)   
   EMBL (11)   
3D Structure (3)   
   PDB (3)   
Protein domain (12)   
   Pfam (12)   
All databases (118)   

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