KEGG   Homo sapiens (human): 129607
Entry
129607            CDS       T01001                                 
Symbol
CMPK2, NDK, TMPK2, TYKi, UMP-CMPK2
Name
(RefSeq) cytidine/uridine monophosphate kinase 2
  KO
K13809  UMP-CMP kinase 2, mitochondrial [EC:2.7.4.14]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00240  Pyrimidine metabolism
hsa01100  Metabolic pathways
hsa01232  Nucleotide metabolism
hsa01240  Biosynthesis of cofactors
Module
hsa_M00052  Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    129607 (CMPK2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.14  UMP/CMP kinase
     129607 (CMPK2)
SSDB
Motif
Pfam: Thymidylate_kin AAA_18 dNK AAA_33 AAA_17 AAA_16 MltA
Other DBs
NCBI-GeneID: 129607
NCBI-ProteinID: NP_997198
OMIM: 611787
HGNC: 27015
Ensembl: ENSG00000134326
UniProt: Q5EBM0
Position
2:complement(6840553..6866635)
AA seq 449 aa
MAFARRLLRGPLSGPLLGRRGVCAGAMAPPRRFVLELPDCTLAHFALGADAPGDADAPDP
RLAALLGPPERSYSLCVPVTPDAGCGARVRAARLHQRLLHQLRRGPFQRCQLLRLLCYCP
GGQAGGAQQGFLLRDPLDDPDTRQALLELLGACQEAPRPHLGEFEADPRGQLWQRLWEVQ
DGRRLQVGCAQVVPVPEPPLHPVVPDLPSSVVFPDREAARAVLEECTSFIPEARAVLDLV
DQCPKQIQKGKFQVVAIEGLDATGKTTVTQSVADSLKAVLLKSPPSCIGQWRKIFDDEPT
IIRRAFYSLGNYIVASEIAKESAKSPVIVDRYWHSTATYAIATEVSGGLQHLPPAHHPVY
QWPEDLLKPDLILLLTVSPEERLQRLQGRGMEKTREEAELEANSVFRQKVEMSYQRMENP
GCHVVDASPSREKVLQTVLSLIQNSFSEP
NT seq 1350 nt   +upstreamnt  +downstreamnt
atggccttcgcccgccggctcctgcgcgggccactgtcggggccgctgctcgggcggcgc
ggggtctgcgctggggccatggctccgccgcgccgcttcgtcctggagcttcccgactgc
accctggctcacttcgccctaggcgccgacgcccccggcgacgcagacgcccccgacccc
cgcctggcggcgctgctggggcccccggagcgcagctactcgctgtgcgtgcccgtgacc
ccggacgccggctgcggggcccgggtccgggcggcgcggctgcaccagcgcctgctgcac
cagctgcgccgcggccccttccagcggtgccagctgctcaggctgctctgctactgcccg
ggcggccaggccggcggcgcacagcaaggcttcctgctgcgcgaccccctggatgaccct
gacacccggcaagcgctgctcgagctgctgggcgcctgtcaggaggcaccacgcccgcac
ttgggcgagttcgaggccgacccgcgcggccagctgtggcagcgcctctgggaggtgcaa
gacggcaggcggctgcaggtgggctgcgcacaggtcgtgcccgtcccggagcccccgctg
cacccggtggtgccagacttgcccagttccgtggtcttcccggaccgggaagccgcccgg
gccgttttggaggagtgtacctcctttattcctgaagcccgggcagtgcttgacctggtc
gaccagtgcccaaaacagatccagaaaggaaagttccaggttgttgccatcgaaggactg
gatgccacgggtaaaaccacggtgacccagtcagtggcagattcacttaaggctgtcctc
ttaaagtcaccaccctcttgcattggccagtggaggaagatctttgatgatgaaccaact
atcattagaagagctttttactctttgggcaattatattgtggcctccgaaatagctaaa
gaatctgccaaatctcctgtgattgtagacaggtactggcacagcacggccacctatgcc
atagccactgaggtgagtgggggtctccagcacctgcccccagcccatcaccctgtgtac
cagtggccagaggacctgctcaaacctgaccttatcctgctgctcactgtgagtcctgag
gagaggttgcagaggctgcagggccggggcatggagaagaccagggaagaagcagaactt
gaggccaacagtgtgtttcgtcaaaaggtagaaatgtcctaccagcggatggagaatcct
ggctgccatgtggttgatgccagcccctccagagaaaaggtcctgcagacggtattaagc
ctaatccagaatagttttagtgaaccgtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (17)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (22)   
   RefSeq(nuc) (4)   
   GenBank (9)   
   EMBL (9)   
Protein domain (7)   
   Pfam (7)   
All databases (80)   

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