KEGG   Homo sapiens (human): 1759
Entry
1759              CDS       T01001                                 
Symbol
DNM1, DEE31, DEE31A, DEE31B, DNM, EIEE31
Name
(RefSeq) dynamin 1
  KO
K01528  dynamin 1/3 [EC:3.6.5.5]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04072  Phospholipase D signaling pathway
hsa04144  Endocytosis
hsa04721  Synaptic vesicle cycle
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa05100  Bacterial invasion of epithelial cells
Disease
H00606  Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    1759 (DNM1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    1759 (DNM1)
 09150 Organismal Systems
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    1759 (DNM1)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    1759 (DNM1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    1759 (DNM1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    1759 (DNM1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1759 (DNM1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.5  Acting on GTP to facilitate cellular and subcellular movement
    3.6.5.5  dynamin GTPase
     1759 (DNM1)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Dynamin
    1759 (DNM1)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    1759 (DNM1)
   RhoA-dependent endocytosis
    1759 (DNM1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   1759 (DNM1)
SSDB
Motif
Pfam: Dynamin_M Dynamin_N GED PH MMR_HSR1
Other DBs
NCBI-GeneID: 1759
NCBI-ProteinID: NP_001275668
OMIM: 602377
HGNC: 2972
Ensembl: ENSG00000106976
UniProt: Q05193
Structure
Position
9:128203379..128255244
AA seq 864 aa
MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI
NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD
LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL
QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA
RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDLAFEATVKKQVQKL
KEPSIKCVDMVVSELTATIRKCSEKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID
IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE
YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE
TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE
QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT
PQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAP
PGVPSRSGQASPSRPESPRPPFDL
NT seq 2595 nt   +upstreamnt  +downstreamnt
atgggcaaccgcggcatggaagatctcatcccgctggtcaaccggctgcaagacgccttc
tctgccatcggccagaacgcggacctcgacctgccgcagatcgctgtggtgggcggccag
agcgccggcaagagctcggtgctcgagaatttcgtaggcagggacttcttgcctcgagga
tctggcattgtcacccgacgtcccctggtcttgcagctggtcaatgcaaccacagaatat
gccgagttcctgcactgcaagggaaagaaattcaccgacttcgaggaggtgcgccttgag
atcgaggccgagaccgacagggtcaccggcaccaacaagggcatctcgccggtgcctatc
aacctccgcgtctactcgccgcacgtgctgaacctgaccctggtggacctgcccggaatg
accaaggtcccggtgggggaccaacctcccgacatcgagttccagatccgagacatgctt
atgcagtttgtcaccaaggagaactgcctcatcctggccgtgtcccccgccaactctgac
ctggccaattctgacgccctcaaggtcgccaaggaggtggacccccagggccagcgcacc
atcggggtcatcaccaagctggacctgatggacgagggcacagatgcccgtgatgtgctg
gagaacaagctgctccccctgcgcagaggctacattggagtggtgaaccggagccagaag
gacattgatggcaagaaggacattaccgccgccttggctgctgaacgaaagttcttcctc
tcccatccatcttatcgccacttggctgaccgtatgggcacgccctacctgcagaaggtc
ctcaatcagcaactgacgaaccacatccgggacacactgccggggctgcggaacaagctg
cagagccagctactgtccattgagaaggaggtggaggaatacaagaacttccgccctgat
gacccagctcgcaagaccaaggccctgctgcagatggtccagcagttcgccgtagacttt
gagaagcgcattgagggctcaggagatcagatcgacacctacgaactgtcagggggagcc
cgcattaaccgaatcttccacgagcgcttccctttcgagctggtcaagatggagtttgat
gagaaggaactccgaagggagatcagctatgctatcaagaatatccatggcattaggacg
ggcctcttcacacctgacctcgcttttgaagccacagtgaaaaagcaggtgcagaagctc
aaagagcccagtatcaagtgtgtggatatggtagtcagtgagctcacagccaccatcaga
aagtgtagcgaaaagctccagcagtacccgcggctacgggaggagatggagcgcatcgtg
accacccacatccgggagcgcgagggccgcactaaggagcaggtcatgcttctcatcgat
atcgagctggcttacatgaacaccaaccatgaggacttcataggctttgccaatgctcag
cagaggagcaaccagatgaacaagaagaagacttcagggaaccaggatgagattctggtc
atccgcaagggctggctgactatcaataatattggcatcatgaaagggggctccaaggag
tactggtttgtgctgactgctgagaatctgtcctggtacaaggatgatgaggagaaagag
aagaaatacatgctgtctgtggacaacctcaagctgcgggacgtggagaagggctttatg
tcgagcaagcatatctttgccctctttaacacggagcagaggaatgtctacaaggattat
cggcagctggagctagcctgtgagacacaggaggaggtggacagctggaaggcctccttc
ctgagggctggcgtgtaccctgagcgtgttggggacaaagagaaagccagcgagaccgag
gagaatggctccgacagcttcatgcattccatggacccacagctggaacggcaagtggag
accatccggaatcttgtggactcatacatggccattgtcaacaagaccgtgagggacctc
atgcccaagaccatcatgcacctcatgattaacaataccaaggagttcatcttctcggag
ctgctggccaacctgtactcgtgtggggaccagaacacgctgatggaggagtcggcggag
caggcacagcggcgcgacgagatgctgcgcatgtaccacgcactgaaggaggcgctcagc
atcatcggcgacatcaacacgaccaccgtcagcacgcccatgcccccgcccgtggacgac
tcctggctgcaggtgcagagcgtaccggccggacgcaggtcgcccacgtccagccccacg
ccgcagcgccgagcccccgccgtgcccccagcccggcccgggtcgcggggccctgctcct
gggcctccgcctgctgggtccgccctggggggggcgccccccgtgccctccaggccgggg
gcttcccctgaccctttcggccctccccctcaggtgccctcgcgccccaaccgcgccccg
cccggggtccccagccgatcgggtcaggcaagtccatcccgtcctgagagccccaggccc
cccttcgacctctaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (5)   
Disease (4)   
   KEGG DISEASE (1)   
   OMIM (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   RefGene (23)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (44)   
   RefSeq(nuc) (6)   
   GenBank (19)   
   EMBL (19)   
3D Structure (14)   
   PDB (14)   
Protein domain (5)   
   Pfam (5)   
All databases (119)   

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