KEGG   Homo sapiens (human): 1781
Entry
1781              CDS       T01001                                 
Symbol
DYNC1I2, DIC74, DNCI2, IC2, NEDMIBA
Name
(RefSeq) dynein cytoplasmic 1 intermediate chain 2
  KO
K10415  dynein cytoplasmic 1 intermediate chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04814  Motor proteins
hsa04962  Vasopressin-regulated water reabsorption
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06515  Regulation of kinetochore-microtubule interactions
  Element
N01295  Rab7-regulated microtubule minus-end directed transport
N01534  Dynein recruitment to the kinetochore
Disease
H02461  Neurodevelopmental disorder with microcephaly
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    1781 (DYNC1I2)
  09142 Cell motility
   04814 Motor proteins
    1781 (DYNC1I2)
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    1781 (DYNC1I2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    1781 (DYNC1I2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    1781 (DYNC1I2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1781 (DYNC1I2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Motor proteins
     Dynein complex
      1781 (DYNC1I2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     1781 (DYNC1I2)
SSDB
Motif
Pfam: Dynein_IC2 WD40 ANAPC4_WD40 Rrn6_K-rich
Other DBs
NCBI-GeneID: 1781
NCBI-ProteinID: NP_001258714
OMIM: 603331
HGNC: 2964
Ensembl: ENSG00000077380
UniProt: Q13409 A0A140VKE9
Structure
Position
2:171687469..171750158
AA seq 638 aa
MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREA
EALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDP
SVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVA
PKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQ
INIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYN
NNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLW
DNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQD
SMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPIT
GIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALF
ACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVG
EQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA
NT seq 1917 nt   +upstreamnt  +downstreamnt
atgtcagacaaaagtgaattaaaggctgagttggaacgtaagaagcagcgactggcccaa
atcagagaggaaaagaagagaaaagaagaagaaaggaaaaaaaaagaaacagaccagaag
aaggaagctgttgctcctgtgcaagaagaatcagatcttgaaaaaaaaaggagagaagct
gaagcattgcttcaaagcatggggctaactccagaatcccccattgttttttctgaatac
tgggtccctcctcctatgtctccatcctccaaatctgtgagcactccaagtgaagctgga
agccaagactctggagatggcgccgtgggatctaggacgctgcattgggatacagatcca
tcagttcttcagcttcactcagattccgatttgggacgaggacctattaaacttggaatg
gctaaaatcacgcaagtcgactttcctcctcgagaaattgtcacgtatacaaaggaaact
cagactccagttatggctcaacccaaagaagatgaagaggaagatgatgatgtagtggct
cctaaaccacctattgaacctgaagaagagaaaactttaaagaaagatgaggaaaatgat
agtaaagctccccctcatgagctgactgaagaagaaaagcaacaaatcttgcactctgag
gaatttttaagtttctttgaccattctacaagaattgtagaaagagctctttctgagcag
attaacatcttctttgactatagtgggagagatttggaagacaaagaaggagagattcaa
gcaggtgctaaactgtcattaaatcgacaattttttgacgaacgttggtcaaagcatcgg
gtggttagttgtttggattggtcatctcagtatccggagttactcgtggcttcctataac
aacaatgaagatgcccctcatgagcctgatggtgtggcccttgtatggaatatgaaatac
aaaaaaactaccccagagtatgtgtttcactgccagtcagctgtgatgtctgccacattt
gcaaaatttcatccaaatcttgttgttggtggtacatattcaggccaaattgtgctttgg
gataaccgtagcaataaaagaactccagtgcaaagaactccactgtcagcagctgcacac
acacaccctgtatattgtgtaaatgttgttggaacacaaaatgctcacaatctgattagc
atctctactgatggaaaaatttgttcatggagtctggacatgctttcccatccacaggat
agcatggagttggttcataaacagtcaaaagcagtagctgtgacatctatgtccttccct
gttggagatgtcaacaactttgttgttgggagtgaagaaggttctgtgtacacagcatgc
cgccatggcagcaaagctggaatcagtgagatgtttgaggggcatcaaggaccaatcact
ggcatccattgtcatgcagctgttggagcagtagacttctcacatctttttgtcacttca
tcgtttgactggacagtaaagctttggacaactaagaataacaagcctttgtattcattt
gaagataatgcagactatgtttatgatgttatgtggtcacctacccacccagccctgttt
gcctgtgtggatggcatggggagattggatttgtggaatctcaataatgacacagaggta
ccaactgccagcatttctgtggagggtaatcctgctcttaatcgtgtgagatggacccat
tctggcagagagattgctgtgggtgattctgaaggacagattgttatatacgatgtggga
gagcagattgctgttccccgcaatgatgaatgggcacggtttggccgaacacttgcagaa
attaatgcaaaccgagctgatgcagaggaggaagcagctacccgaatacctgcttag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Network (4)   
   KEGG NETWORK (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (15)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (64)   
   RefSeq(nuc) (12)   
   GenBank (26)   
   EMBL (26)   
3D Structure (10)   
   PDB (10)   
Protein domain (4)   
   Pfam (4)   
All databases (126)   

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