KEGG   Homo sapiens (human): 192111
Entry
192111            CDS       T01001                                 
Symbol
PGAM5, BXLBV68
Name
(RefSeq) PGAM family member 5, mitochondrial serine/threonine protein phosphatase
  KO
K15637  serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04137  Mitophagy - animal
hsa04217  Necroptosis
hsa04668  TNF signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    192111 (PGAM5)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    192111 (PGAM5)
  09143 Cell growth and death
   04217 Necroptosis
    192111 (PGAM5)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     192111 (PGAM5)
SSDB
Motif
Pfam: His_Phos_1
Other DBs
NCBI-GeneID: 192111
NCBI-ProteinID: NP_001164014
OMIM: 614939
HGNC: 28763
Ensembl: ENSG00000247077
UniProt: Q96HS1
Structure
Position
12:132710842..132722734
AA seq 289 aa
MAFRQALQLAACGLAGGSAAVLFSAVAVGKPRAGGDAEPRPAEPPAWAGGARPGPGVWDP
NWDRREPLSLINVRKRNVESGEEELASKLDHYKAKATRHIFLIRHSQYHVDGSLEKDRTL
TPLGREQAELTGLRLASLGLKFNKIVHSSMTRAIETTDIISRHLPGVCKVSTDLLREGAP
IEPDPPVSHWKPEAVQYYEDGARIEAAFRNYIHRADARQEEDSYEIFICHANVIRYIVCR
ALQFPPEGWLRLSLNNGSITHLVIRPNGRVALRTLGDTGFMPPDKITRS
NT seq 870 nt   +upstreamnt  +downstreamnt
atggcgttccggcaggcgctgcagctggcggcctgcgggctggccgggggctcggccgcc
gtgctcttctcggccgtggcggtagggaagccgcgcgcaggcggggacgcggagccacgc
ccggctgagccgccggcctgggcggggggcgcgcggccgggccccggtgtctgggacccc
aactgggacaggcgagaaccactgtctctgatcaacgtgcggaagaggaacgtggaatct
ggggaagaagagctggcgtccaagctggaccactacaaagccaaggccacgcggcacatc
ttcctcatcaggcattcccagtaccacgtggatggctccctggagaaggaccgcactctg
accccgctgggtcgggagcaggctgaactcactgggctccgcctggcaagcttggggttg
aagtttaataaaatcgtccattcgtctatgacgcgcgccatagagaccaccgatatcatc
agccggcacctgccaggcgtctgcaaagtcagcacagatctgctgcgggaaggcgccccc
atcgagccagacccgcccgtgtctcattggaagccggaagctgtgcagtattacgaagac
ggagcccggatcgaggccgccttccggaactacatccaccgcgcagatgccaggcaggag
gaggacagttacgagatcttcatctgtcacgccaacgtcatccgctacatcgtgtgcaga
gcactgcagtttcctcctgaaggctggctccggctctccctcaataatggcagcatcacc
cacctggtgatccgacccaacggccgagttgcgctcaggaccctcggggacacggggttc
atgcctcccgacaagatcactcgatcctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (21)   
   RefSeq(nuc) (3)   
   GenBank (9)   
   EMBL (9)   
3D Structure (9)   
   PDB (9)   
Protein domain (1)   
   Pfam (1)   
All databases (66)   

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