KEGG   Homo sapiens (human): 201626
Entry
201626            CDS       T01001                                 
Symbol
PDE12, 2'-PDE, 2-PDE
Name
(RefSeq) phosphodiesterase 12
  KO
K19612  2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    201626 (PDE12)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    201626 (PDE12)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.13  Exoribonucleases producing 5'-phosphomonoesters
    3.1.13.4  poly(A)-specific ribonuclease
     201626 (PDE12)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA degradation factors
   3'-5' decay
    Other 3'-5' decay factors
     201626 (PDE12)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial transcription and translation factors
   Other mitochondrial DNA transcription and translation factors
    201626 (PDE12)
SSDB
Motif
Pfam: PDE12-like_N Exo_endo_phos DUF5411
Other DBs
NCBI-GeneID: 201626
NCBI-ProteinID: NP_808881
OMIM: 616519
HGNC: 25386
Ensembl: ENSG00000174840
UniProt: Q6L8Q7
Structure
Position
3:57556274..57656495
AA seq 609 aa
MWRLPGARAALRVIRTAVEKLSRAEAGSQTAAGAMERAVVRCVPSEPKLSLSFALADGSH
KNMQRDQSEPLGRVLSRIATNALKGHAKAAAAKKSRKSRPNASGGAACSGPGPEPAVFCE
PVVKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVC
PKLSLEFGDPASSLFRWYKEAKPGAAEPEVGVPSSLSPSSPSSSWTETDVEERVYTPSNA
DIGLRLKLHCTPGDGQRFGHSRELESVCVVEAGPGTCTFDHRHLYTKKVTEDALIRTVSY
NILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADVICLQEVDRAVFSDS
LVPALEAFGLEGVFRIKQHEGLATFYRKSKFSLLSQHDISFYEALESDPLHKELLEKLVL
YPSAQEKVLQRSSVLQVSVLQSTKDSSKRICVANTHLYWHPKGGYIRLIQMAVALAHIRH
VSCDLYPGIPVIFCGDFNSTPSTGMYHFVINGSIPEDHEDWASNGEEERCNMSLTHFFKL
KSACGEPAYTNYVGGFHGCLDYIFIDLNALEVEQVIPLPSHEEVTTHQALPSVSHPSDHI
ALVCDLKWK
NT seq 1830 nt   +upstreamnt  +downstreamnt
atgtggaggctcccaggcgcccgcgccgcgcttcgggtgatccggacggcggtggagaag
ctgagccgggctgaagcggggagccagacagcggcgggagcgatggagcgcgctgtagtg
cgctgcgtaccttcggaacccaagctgagcctgtcattcgctttggctgatggtagccac
aagaacatgcagcgcgaccagagcgagccgctgggtcgagtcctcagccgcatcgctacc
aatgccctaaagggtcacgctaaggcggccgccgccaagaagagcaggaagagccggccg
aatgctagcggcggtgcggcctgttcagggccggggcctgagccggctgtgttctgcgag
cccgtggtgaagctgtactaccgggaagaggcagtggctgaggacgtgctcaacgtggat
gcctggcaagacggcgcggtgctgcagatcggcgatgttaagtacaaggtggagcgcaac
ccgcccgccttcaccgaactgcagttgccgcgctacatcatggccgggttccctgtgtgc
cccaaactcagcctcgaatttggggatcccgccagctcccttttccgctggtataaggaa
gccaagcccggagcggcggagcccgaggtcggtgtcccctcgtcattgtctccctcctca
ccttcttcttcttggactgagactgatgtggaggagcgtgtctacaccccgtccaatgcc
gacatcgggctaaggctcaagcttcactgcaccccaggcgatgggcagcgctttgggcac
agccgggagttggaaagtgtgtgtgtggtagaggctgggcctggcacctgcacttttgac
caccggcatctctacacgaagaaggtgactgaggacgctctcatccgcactgtctcttac
aacatcctggcagacacgtacgcgcagactgagttctcgcgaacggttctgtacccatac
tgtgccccctacgccctggagctcgactaccgccagaaccttatccagaaggaactcacc
ggctacaacgccgatgtcatctgtttgcaggaggttgaccgcgcagtgttttctgacagc
ttggtacccgccctagaggccttcgggctcgagggggtgtttcgaatcaagcagcacgaa
ggcctggccactttctaccgaaagtctaagttcagccttcttagccagcatgacatttca
ttctacgaagccctcgagtccgacccacttcacaaagaactgctggagaaactagttttg
tacccatcagcgcaggagaaggtgctccagagatcttctgttcttcaggtttcagttctt
cagtctacaaaggactcttctaaaaggatatgtgttgctaatacccatctttactggcat
cctaaaggtgggtatattcgcctcattcaaatggcagtagccttggctcacataagacat
gtttcatgtgatctgtatcctggcataccagttatattttgtggggactttaatagtaca
ccatcaacaggaatgtatcattttgtcatcaatggcagcattccagaggatcatgaagac
tgggcttccaatggggaggaggaaagatgcaatatgtctcttacacatttcttcaagctg
aaaagtgcttgtggtgaacctgcttacacaaattatgttggtggctttcatggatgtcta
gattacattttcattgacttaaatgctttagaggttgaacaggtgattccattacctagt
catgaagaagttaccacccaccaggccttacctagtgtttcccatccctctgatcacata
gcacttgtatgtgatttaaaatggaaatag

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Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (21)   
   RefSeq(nuc) (3)   
   GenBank (9)   
   EMBL (9)   
3D Structure (3)   
   PDB (3)   
Protein domain (3)   
   Pfam (3)   
All databases (54)   

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