KEGG   Homo sapiens (human): 221037
Entry
221037            CDS       T01001                                 
Symbol
JMJD1C, KDM3C, TRIP-8, TRIP8
Name
(RefSeq) jumonji domain containing 1C
  KO
K11449  jumonji domain-containing protein 1C [EC:1.14.11.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription (cancer)
  Element
N00119  MLL-AF4 fusion to transcriptional activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    221037 (JMJD1C)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    221037 (JMJD1C)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   Histone demethylases
    221037 (JMJD1C)
SSDB
Motif
Pfam: JmjC C1_2 zf-C5HC2 FYVE
Other DBs
NCBI-GeneID: 221037
NCBI-ProteinID: NP_116165
OMIM: 604503
HGNC: 12313
Ensembl: ENSG00000171988
UniProt: Q15652
Structure
Position
10:complement(63167225..63521890)
AA seq 2540 aa
MAVETRAELVGKRFLCVAVGDEARSERWESGRGWRSWRAGVIRAVSHRDSRNPDLAVYVE
FDDLEWDKREWVKVYEDFSTFLVEYHLIWAKRNDPSQTQGSKSKQIQWPALTFKPLVERN
IPSSVTAVEFLVDKQLDFLTEDSAFQPYQDDIDSLNPVLRDNPQLHEEVKVWVKEQKVQE
IFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQM
TFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNT
HQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEK
KLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNE
KAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLP
QECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPN
VSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKYVSYI
SPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKA
TYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETTKSPLIIDKNEHFTVYRDPALI
GSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALTPAPHLLAGSSSQTPLPTINTH
PLTSGPHHAVHHPHLLPTVLPGVPTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQ
SPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLPSSKWVHPENAVNAEASLRRNS
PSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKITAHSSPPLTKTLVDHHKEELER
KAFMEPLRSVASTSAKNDLDLNRSQTGKDCHLHRHFVDPVLNQLQRPPQETGERLNKYKE
EHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSPKSHIIKQDMDVERSVSDLYKM
KHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFI
TSLSKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSM
PALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDS
QANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPA
MQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSV
PSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQ
PVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNAS
ETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSE
EDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKR
TYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKE
RSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSK
KGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQYDDEAMSLWTHENFEDDELDIE
TSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVC
QKCGFVVCLDCYKAKERKSSRDKELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTDLLDAM
HTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQVLQNVLNHSNKISLCMPESQQQNTPP
KSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIKEER
EQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSK
SGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIISAVDENNKLYSDIPHS
WICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQA
DLLNCKDSIISNANVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYED
LLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDHDIGTTNLHIEVS
DVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVD
KIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVL
PAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRLLKEEINYDDKLQVKNILYHAV
KEMVRALKIHEDEVEDMEEN
NT seq 7623 nt   +upstreamnt  +downstreamnt
atggcggtagagacgcgggcagagctggtgggtaagcggttcctgtgtgtggcggtcggc
gacgaggcacgttcggagcgctgggagagcggacgcggctggcgaagctggcgagcgggg
gtcatccgagccgtgtcacacagggacagccgcaatccggacctggcggtgtatgtggaa
tttgatgatcttgaatgggataaacgagagtgggttaaagtttatgaagatttttcaact
ttcttggtggaataccacttaatctgggccaaaaggaatgaccctagccagactcaggga
tcaaagagcaaacagattcagtggcctgcattgactttcaaacctctggttgaaagaaat
atacccagttcagtcactgcagtagaattccttgtagataagcaactggattttttaact
gaagatagtgcctttcagccctaccaggacgacatagacagcctaaacccagttctcagg
gacaacccgcagcttcatgaggaagtgaaagtctgggtaaaggaacaaaaggttcaggag
atttttatgcaaggtccttattccttaaatggatacagagtgagagtatatagacaagac
tctgccacccagtggtttactggcataattactcatcatgatctcttcacccgcaccatg
atcgttatgaatgatcaggtactagaaccacagaatgtcgatccttctatggttcaaatg
acctttctagatgatgttgttcactctttgttaaaaggtgaaaatattggcattacatca
cgacgcaggtctcgtgccaatcaaaacgtcaacgctgttcacagccattatacacgtgcc
caagcaaatagtcccagaccagcaatgaactcccaagctgctgtaccaaaacagaataca
caccagcaacagcaacaaagaagtatccgtccaaataagaggaagggctcagatagcagt
ataccagatgaagagaagatgaaggaggaaaaatatgattatatatcacgaggagaaaat
cctaaaggtaaaaacaaacacttgatgaataaaagaaggaaacctgaggaggatgaaaag
aaactaaatatgaaaagacttcgaactgacaatgtttcagacttttctgagagcagtgac
tcagaaaattcaaataagagaataatagataattcctcagaacagaagccagagaatgaa
ttgaaaaataaaaatacttcaaaaataaatggagaagaaggaaaaccccataataatgag
aaggcaggagaagagaccctaaaaaatagccagcctccctgggatcaaatacaggaagat
aaaaaacatgaagaagcagagaagcggaagtctgttgacactcagcttcaagaagatatg
attattcattcgtcagaacagtccacagtttctgatcataattctaatgatttacttcct
caggaatgcaatatggataaaacacataccatggaattgctaccaaaggagaagtttgta
tccagaccacccacaccaaaatgtgttattgatattacaaatgacactaatttagaaaag
gtggctcaggaaaactcaagtacctttggccttcagacacttcagaaaatggatcctaat
gttagtgattcaaaacactctattgcaaatgcaaaattcttggaaacagcaaaaaaagat
tctgaccagagctgggtcagtgatgtagttaaagtggatctaacccaatcaagtgttaca
aatgcttcttcaggaaatgatcacttgaacatggaaaaagagaagtatgtctcttacatt
tctcctttaagtgcagtttctgtcatggaagataagctgcataagcgaagtccacctcca
gagactataaaatctaaacttaatacttcagtagatactcacaagataaaatccagccca
tcacctgaagttgttaaacccaaaataactcattctcctgattctgtaaagtctaaggcc
acttatgtgaacagccaagctactggtgaaagaagattggcaaataagatagaacatgag
ctatcaagatgcagttttcatccaattcctactcgaagcagtacattagaaactacaaag
agtcctcttatcattgataaaaatgagcattttacagtttacagagatcctgcacttatt
gggtcagaaacaggagctaatcatatttcacctttcctaagccagcatccttttcctctt
cactcctcatctcatagaacctgtttaaatccaggtacccatcatcctgccttaactcct
gcaccccatttactagccggatcatctagtcaaactccattacctaccattaacactcat
cctctgactagtggtccacaccatgctgttcatcaccctcatttacttcccactgtgtta
cctggagtgcctactgcctccttacttggtggccacccacgactagagagtgctcatgcc
agcagcttgagccacttagcgctagcacaccagcaacaacaacagttgttacagcaccag
tcacctcatcttcttggacaagcccatccttctgcttcatataatcagcttggactttat
ccaattatttggcagtatccaaatggaacacatgcatactcaggacttggtttgccttct
tctaagtgggttcacccagaaaatgcagttaatgctgaagcttcattaaggaggaattct
cccagtccttggctacatcagcccacccctgtgacctcagcagatggtattggattactt
agtcacattcctgtcagaccttccagtgcagagcctcatcggcctcttaaaattacagcc
cattccagtccaccattgacaaaaactttagtagatcatcataaggaagaattagaaaga
aaagcttttatggaaccattacggtctgttgcatccacatcagccaaaaatgacctggat
ctaaataggtcacagactggaaaagattgtcacttacataggcattttgtggatccagta
ttaaatcagttacagaggccaccccaggagactggagagaggttaaacaaatacaaagag
gaacaccgtcgaattcttcaagaaagtattgatgttgctccctttacaactaaaatcaag
ggacttgagggtgagagagagaattattccagagtggcatcatcatcttccagtcctaaa
agccatatcatcaaacaagatatggatgtagaacgctcagtatcagatctttataaaatg
aagcactcagtgcctcagagtttaccccaaagtaactatttcactacattgtctaatagt
gtggtcaatgaaccaccaagatcatacccatccaaagaagtttcaaatatttacggtgat
aaacagagtaatgcccttgcagcggcagcagctaatcctcaaactctgacttcatttata
acatctctttcaaagcctccacctttgattaaacaccaaccagaaagtgaaggtttagta
ggcaagataccagaacatcttccacatcagattgcatctcactcagtaacaaccttcaga
aatgattgtaggagtcctacccatttgacagtttcttctacaaatacactccgcagtatg
cctgcattacatagagcaccagtatttcacccaccaatccatcacagcctggaaagaaag
gaaggcagctatagtagtctttcccctccaactttaactccggtgatgccagtaaatgct
ggtggtaaagttcaagaatcacagaagcctccaactctaatacccgaaccaaaagactcc
caggcaaattttaagagttcttcagaacagagtttgacggagatgtggagacctaataat
aacctcagcaaagagaaaactgaatggcatgtggagaaaagcagcggaaagttacaggct
gctatggcatctgtcattgtgcgtccatcttctagtacaaaaactgatagtatgccagca
atgcagttagcttctaaagatcgtgttagtgaaagatcttcagctggggcacataaaaca
gattgcctcaaactagcagaagccggagaaactggaagaatcattttgccaaatgtgaat
tcagacagtgttcacacaaaatctgaaaaaaactttcaggctgtctcacagggcagtgtt
cccagttcagtcatgtctgctgtaaatacgatgtgtaataccaaaacggatgtaatcaca
tctgctgccgatactaccagtgtttccagctggggtggttcagaagtaatttcctcttta
tcaaataccattttggcctctacatcatcagaatgtgtatcttcaaaaagtgtcagtcag
ccagtggctcaaaaacaagaatgcaaggtcagcaccacagcaccagttacattagccagt
agtaagacaggaagtgttgttcaacccagttctgggttctcaggcacaactgattttatc
catttaaaaaagcacaaggcagcattggctgcagctcagtataaaagtagtaatgccagt
gagactgaacctaatgctataaaaaatcagacactttcagcctcccttcctctggatagc
actgtaatctgtagtacaattaacaaagcaaactctgtaggaaatgggcaagcttcccag
acaagtcaaccaaactaccatactaaactgaaaaaggcctggctcaccagacactcagaa
gaagataaaaatactaataaaatggaaaattcagggaattctgtatcagaaattattaag
ccatgttctgtcaacttaatagcctctacatctagtgatatacaaaatagtgtagatagt
aagatcatagttgataaatatgtaaaagatgataaagtcaacaggagaaaagccaaaaga
acttatgaatctggctctgaaagtggagactcagatgaaagtgaaagcaagtcagagcaa
aggactaaaagacaacctaagccaacttacaaaaagaagcaaaatgatttgcaaaagaga
aaaggtgaaatagaagaagatttgaaacccaatggagttctcagcaggagtgccaaagaa
agaagtaaactgaagttgcaaagcaacagtaatactggcattcctcgttcagtattgaaa
gattggcgtaaagtcaagaagctgaagcaaactggggaatcctttttacaggatgactcc
tgctgtgagatagggcctaatttacaaaagtgtcgagaatgtagacttattcgcagtaaa
aaaggagaagaaccagctcactcaccagtattttgtagattttactactttagacggttg
tcatttagtaaaaacggagtagttagaatagatggtttctcttctcctgaccaatatgat
gatgaagctatgagtttgtggacacatgaaaattttgaagatgatgaactagatatagag
acttctaaatatatcttggatataataggtgataagttctgtcaattagtaacatctgaa
aaaacagctttgtcctgggtgaaaaaggatgccaaaattgcctggaaaagagcagtgaga
ggagtccgggagatgtgtgatgcatgtgaagcaacattgtttaacattcactgggtctgc
caaaaatgtggatttgtggtctgcttagattgttacaaggcaaaggaaaggaagagttct
agagataaagaactatatgcttggatgaagtgtgtgaagggacagcctcatgatcacaaa
catttaatgccaacccaaattatacctggttctgttttgacagatcttctagatgccatg
cacactcttagggaaaaatatggtattaaatcccattgtcattgtactaacaaacagaat
ttacaagttggaaattttcctacaatgaatggtgtatctcaagttttacagaatgttctt
aatcacagtaataaaatttctctgtgcatgcctgagtctcagcagcaaaatactcctccg
aagtctgagaaaaatggtggcagcagcccagagagtgatgtaggcacagataacaagtta
actcctccagaatcccagtcaccactgcactggttagcagatcttgcagagcaaaaagcc
agagaggaaaaaaaagaaaacaaagaacttacccttgaaaaccaaattaaagaagaaaga
gaacaagacaactctgaatctccaaatggcagaacatcacctcttgtgtcccagaataat
gaacaaggctcaaccttacgggatttgctgactacaacagctggaaagctacgtgtgggg
tctacagatgctggcattgcctttgccccagtatattcaatgggagccccaagtagcaaa
agtggacggactatgcctaacattcttgatgacataattgcttcagttgttgaaaacaaa
attccaccaagtaaaacctccaagataaatgtaaaaccagagcttaaagaagagcctgaa
gaaagcataatatctgcagtggatgaaaataataaattatacagtgatataccacattct
tggatctgtgagaagcatattttatggcttaaggattataagaatagcagtaattggaag
cttttcaaagaatgttggaaacaaggacagcctgcagtggtttctggtgtgcataagaaa
atgaacattagcctatggaaggcggaatcaattagtcttgattttggagaccaccaagct
gatctcctgaactgcaaagatagcatcatttcaaatgccaatgttaaggaattctgggat
ggttttgaagaagtttcaaaacggcagaaaaacaagagtggagaaacagttgttttaaaa
ttgaaagactggccttcaggagaagacttcaagactatgatgccagcaagatacgaagat
cttttaaaaagtctgccattgccagaatattgtaatccagaaggaaaattcaatttggcc
tctcatttgccaggattttttgtacgtcctgatctaggacccaggttgtgcagtgcctat
ggtgtagttgctgctaaagatcatgatataggaacaacaaatctccatattgaagtttct
gatgttgtaaatatactagtttatgttggcatagcaaaaggaaatggcattctctcaaaa
gcaggaattctcaagaaatttgaggaagaagatttggatgacattttaaggaaaagattg
aaggactcaagtgaaatacctggtgctctgtggcatatttatgctgggaaagatgttgac
aagataagggaatttcttcaaaagatttcaaaagaacaaggccttgaagttctaccagaa
catgatccaatacgtgaccaaagttggtatgtgaacaaaaagctccgtcaaaggctgctt
gaagaatatggagtcagaacctgtactcttattcagttccttggtgatgctattgttttg
ccagcgggagcacttcatcaggttcagaattttcacagctgtattcaggtaactgaagat
tttgtgtctccagaacatcttgtagagtcatttcatttaacacaggaactgagacttttg
aaggaagaaatcaattatgatgataaactacaggttaaaaatattttgtatcatgcagtc
aaagaaatggtgagagccttgaagatacacgaggatgaagtagaggatatggaagaaaat
taa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (47)   
   KEGG ORTHOLOGY (1)   
   RefGene (37)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (16)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (66)   
   RefSeq(nuc) (16)   
   GenBank (25)   
   EMBL (25)   
3D Structure (2)   
   PDB (2)   
Protein domain (4)   
   Pfam (4)   
All databases (142)   

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