KEGG   Homo sapiens (human): 222484
Entry
222484            CDS       T01001                                 
Symbol
LNX2, PDZRN1
Name
(RefSeq) ligand of numb-protein X 2
  KO
K10692  ligand of Numb protein X 1/2 [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    222484 (LNX2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     222484 (LNX2)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Ligand of Numb proteins
    222484 (LNX2)
SSDB
Motif
Pfam: PDZ PDZ_6 PDZ_2 zf-C3HC4_2 zf-C3HC4 zf-RING_UBOX zf-RING_2 zf-C3HC4_3 zf-C3HC4_4 zf-RING_5 zf-rbx1 TRAF3_RING zf-Nse zf-RING_11
Other DBs
NCBI-GeneID: 222484
NCBI-ProteinID: NP_699202
OMIM: 609733
HGNC: 20421
Ensembl: ENSG00000139517
UniProt: Q8N448
Structure
Position
13:complement(27545913..27621107)
AA seq 690 aa
MGTTSDEMVSVEQTSSSSLNPLCFECGQQHWTRENHLYNYQNEVDDDLVCHICLQPLLQP
LDTPCGHTFCYKCLRNFLQEKDFCPLDRKRLHFKLCKKSSILVHKLLDKLLVLCPFSSVC
KDVMQRCDLEAHLKNRCPGASHRRVALERRKTSRTQAEIENENGPTLLDPAGTLSPEADC
LGTGAVPVERHLTSASLSTWSEEPGLDNPAFEESAGADTTQQPLSLPEGEITTIEIHRSN
PYIQLGISIVGGNETPLINIVIQEVYRDGVIARDGRLLAGDQILQVNNYNISNVSHNYAR
AVLSQPCNTLHLTVLRERRFGNRAHNHSDSNSPREEIFQVALHKRDSGEQLGIKLVRRTD
EPGVFILDLLEGGLAAQDGRLSSNDRVLAINGHDLKYGTPELAAQIIQASGERVNLTIAR
PGKPQPGNTIREAGNHSSSSQHHTPPPYYSRPSSHKDLTQCVTCQEKHITVKKEPHESLG
MTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDVLLNINGIDLTNLSHSEAVAMLK
ASAASPAVALKALEVQIVEEATQNAEEQPSTFSENEYDASWSPSWVMWLGLPSTLHSCHD
IVLRRSYLGSWGFSIVGGYEENHTNQPFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTV
GMSHSALVPMLKEQRNKVTLTVICWPGSLV
NT seq 2073 nt   +upstreamnt  +downstreamnt
atgggaacaacaagtgatgagatggtgtctgtggaacagacctcctcctcttctctaaac
cccctgtgttttgaatgtggccaacagcactggacaagagaaaaccatttgtacaattac
cagaatgaagtggatgatgacctagtctgccatatttgccttcaacctctgctgcagcca
ctagacacaccctgtggacatacattctgctacaagtgcctcagaaactttttacaagag
aaagatttctgtccgttggaccggaaaagacttcattttaagttgtgcaagaagtctagt
attctagttcataaactcctagacaaattattagttttatgtccattttcttcagtgtgc
aaagatgtaatgcaacgttgtgatctggaggcacatctcaaaaacagatgtcctggagct
tctcatcggagagttgccctggagagaaggaaaactagtagaactcaagcagagattgag
aatgaaaatgggcccactctactagatcctgcaggtaccttatctccagaagcagactgt
ttggggacaggcgcagtgcctgtggagcggcacttgacatcagcgtctctttccacatgg
agtgaggagcctggccttgacaaccctgcctttgaggagagcgctggagctgacaccaca
caacagccacttagtttaccagaaggagaaatcaccacgattgaaattcatcggtccaat
ccttacattcagttaggaatcagcattgtgggtggcaacgaaacacctttgattaacatt
gtcatccaggaggtctatcgggatggggtcattgccagagacgggagacttcttgctgga
gaccagattcttcaggtcaacaactacaatatcagcaatgtgtcccataactatgcccga
gctgtcctttcccagccctgcaacacactgcatcttactgtgcttcgagagaggcgcttt
ggcaaccgagcacacaaccattctgatagtaactctccacgagaagagattttccaagtg
gctcttcataaacgggactctggtgaacagcttggcattaaattggtgcgaaggacagat
gagccaggggtttttattcttgacctgttggaaggggggttggctgcccaggacggcagg
ctaagcagcaatgaccgagtgctggccatcaatgggcacgacctgaagtatggaactccg
gagcttgctgcccagattattcaggccagtggagagagagtgaatttaacaattgctaga
ccagggaaaccccagcctggtaacaccattagagaagcaggaaatcatagcagcagcagc
cagcaccacacaccaccaccgtattatagcagaccaagctcacataaggatcttactcag
tgtgttacatgccaagaaaaacacattactgtaaagaaggaaccacatgaatcccttggc
atgaccgttgctgggggcaggggaagtaagagtggtgagctgcccatctttgtgaccagt
gtgccaccccatggctgccttgcacgagatggcagaataaagagaggtgatgtgttgcta
aatatcaacggcattgatttgaccaatttaagtcacagtgaggcagttgcaatgctgaaa
gccagtgccgcgtcccctgctgttgcccttaaagcacttgaggtccagattgttgaggag
gcgactcagaacgcggaggagcagccgagtactttcagcgaaaatgagtatgatgccagt
tggtccccatcatgggtcatgtggcttgggcttcccagcacacttcatagctgccacgat
atagttttacgaagaagttacttgggaagttggggctttagtatcgttggtggatatgaa
gagaaccacaccaatcagccttttttcattaaaactattgtcttgggaactcctgcttat
tatgatggaagattaaagtgtggtgacatgattgtggccgtaaatgggctgtcaaccgtg
ggcatgagccactctgcactagttcccatgttgaaggagcagaggaacaaagtcactctg
accgttatttgttggcctggcagccttgtatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (20)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (18)   
DNA sequence (30)   
   RefSeq(nuc) (18)   
   GenBank (6)   
   EMBL (6)   
3D Structure (7)   
   PDB (7)   
Protein domain (14)   
   Pfam (14)   
All databases (88)   

Download RDF
DBGET integrated database retrieval system