KEGG   Homo sapiens (human): 2241
Entry
2241              CDS       T01001                                 
Symbol
FER, PPP1R74, TYK3, p94-Fer
Name
(RefSeq) FER tyrosine kinase
  KO
K08889  tyrosine-protein kinase Fer [EC:2.7.10.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04520  Adherens junction
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    2241 (FER)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2241 (FER)
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    2241 (FER)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    2241 (FER)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     2241 (FER)
Protein kinases [BR:hsa01001]
 Non-receptor tyrosine kinases
  FES family
   2241 (FER)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     2241 (FER)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Bin/Amphiphysin/Rvs (BAR) family proteins
   F-BAR proteins
    2241 (FER)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 FCH ABC1 PGDH_inter
Other DBs
NCBI-GeneID: 2241
NCBI-ProteinID: NP_005237
OMIM: 176942
HGNC: 3655
Ensembl: ENSG00000151422
UniProt: P16591 W0S0X4
Structure
Position
5:108747897..109196841
AA seq 822 aa
MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQ
MNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQ
IEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHM
LHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEI
VNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNL
TAESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQAL
EELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVNYEEDARSVTSMERKERLSK
FESIRHSIAGIIRSPKSALGSSALSDMISISEKPLAEQDWYHGAIPRIEAQELLKKQGDF
LVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITK
KSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQE
LKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQ
LVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLK
QIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMS
APQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT
NT seq 2469 nt   +upstreamnt  +downstreamnt
atggggtttgggagtgacctgaagaattcacatgaagcagtgttaaaattgcaagactgg
gaattacggttactggaaacagtaaagaaatttatggccctgagaataaaaagtgataaa
gaatatgcatctactttacagaacctttgtaatcaagttgataaggaaagtactgtccaa
atgaattatgtcagcaacgtatccaagtcttggctacttatgattcagcagacagaacaa
cttagtaggataatgaagacacatgcagaggacttgaactctggacctttacacaggctc
accatgatgattaaggacaagcagcaggtgaagaaaagttacataggtgttcatcagcag
atagaggcagagatgatcaaggttaccaaaacagaattggagaagttaaaatgcagctat
agacaattaataaaagaaatgaattctgccaaagagaaatataaagaagctttagctaaa
gggaaggaaactgaaaaggccaaggaacgatacgacaaagccacaatgaaacttcatatg
ttgcacaatcagtatgtattggcgttgaaaggggcacagctccatcagaatcagtattat
gatatcacacttcccctgcttctggactccttacaaaagatgcaagaagaaatgataaaa
gcactcaaaggtatatttgatgaatacagccagataaccagtcttgtcacagaggaaata
gtgaatgtccataaagagattcaaatgtcggttgaacagatagatcctagtacagaatac
aataatttcatagatgttcacagaacaacggctgctaaagaacaagaaatagagtttgat
acttccttactggaagaaaatgaaaatcttcaggcaaatgagatcatgtggaataactta
acagcagaaagtttgcaagtaatgttgaaaacgttagcggaagaacttatgcaaacacag
cagatgcttttaaacaaggaggaggctgttttggagttagagaagagaattgaagaatct
tctgaaacttgtgagaagaagtctgatattgtgcttctgctaagccaaaaacaggcactt
gaagaactgaaacagtcagtccagcagctgagatgcactgaagcaaagttttcagcacag
aaggaattactagagcaaaaagtgcaagaaaatgatgggaaagagccacctccagtagta
aattatgaagaagatgcacgatcagttacatctatggaaagaaaggagaggctatccaaa
tttgaatctattcgtcattcaattgctggaataattaggtctccaaaatctgcactgggc
tcttcagcactttctgatatgatctccatcagtgagaagcctttggcagaacaggactgg
taccatggtgcaattcccagaatagaagctcaagaactgttaaaaaaacaaggagacttt
ttggtgcgagagagtcatgggaaacctggtgaatatgtcctttctgtatattctgatgga
cagaggagacattttatcatacaatatgttgataacatgtatcgattcgagggcactggg
ttttcaaacattcctcaacttatagatcatcactatacaacaaaacaggtcatcactaag
aaatcaggtgtagttctgctgaatcctattcctaaggacaagaaatggattctcagtcat
gaagatgtcatattgggagaattactgggcaagggaaattttggtgaagtatataagggc
acattaaaggataaaacttctgttgctgttaaaacatgtaaagaagatcttcctcaggaa
ttgaaaataaaatttttacaagaagccaaaattctcaagcaatatgatcatcccaatatt
gtcaaacttataggagtttgcacacaaagacagcctgtctacatcattatggaactggtt
tcaggaggtgatttcctcacctttctgagaaggaagaaggatgaactaaaactcaaacag
ttagtgaaattttcattagacgctgctgctggtatgttgtatctcgagagtaaaaactgt
atacacagggaccttgctgcaagaaactgcctggtaggtgaaaataatgttctgaaaatc
agtgactttggaatgtctcgtcaagaggatggtggagtgtattcatcttctggcttaaag
cagattcccattaaatggacagcaccggaagctcttaattatgggagatacagttcagag
agtgacgtgtggagctttggcatccttctctgggagaccttcagcttaggggtttgtccg
taccctggaatgacaaatcagcaagcaagagagcaagtagaaagaggataccggatgtca
gctccccagcactgtccagaggatatttccaaaatcatgatgaagtgttgggattataaa
cctgaaaatcgccctaagttcagtgaacttcagaaagagctcactatcatcaagagaaaa
ctcacatag

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (44)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (41)   
DNA sequence (78)   
   RefSeq(nuc) (48)   
   GenBank (15)   
   EMBL (15)   
3D Structure (2)   
   PDB (2)   
Protein domain (6)   
   Pfam (6)   
All databases (147)   

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