KEGG   Homo sapiens (human): 23020
Entry
23020             CDS       T01001                                 
Symbol
SNRNP200, ASCC3L1, BRR2, HELIC2, RP33, U5-200KD
Name
(RefSeq) small nuclear ribonucleoprotein U5 subunit 200
  KO
K12854  pre-mRNA-splicing helicase BRR2 [EC:3.6.4.13]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
Disease
H00527  Retinitis pigmentosa
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    23020 (SNRNP200)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    23020 (SNRNP200)
Spliceosome [BR:hsa03041]
 Complex B
  U4/U6.U5 tri-snRNP components
   U5 snRNP specific factors
    23020 (SNRNP200)
 Complex C
   U5 SnRNP specific factors
    23020 (SNRNP200)
SSDB
Motif
Pfam: Sec63 DEAD Helicase_PWI ResIII Helicase_C BRR2_plug AAA_22 AAA_30 PhoH SWI2_SNF2 DUF603
Other DBs
NCBI-GeneID: 23020
NCBI-ProteinID: NP_054733
OMIM: 601664
HGNC: 30859
Ensembl: ENSG00000144028
UniProt: O75643
Structure
Position
2:complement(96274338..96305546)
AA seq 2136 aa
MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTK
PQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFI
QAALGDQPRDILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQTDDTRYHVLVNLGKKIT
DYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTL
SANLVASGELMSSKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDR
ECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFL
YQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGS
HFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKT
LNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIY
IAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKG
GERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYED
VATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQ
VLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPY
GFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGR
WTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDM
LNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTA
ALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSL
SSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMAD
MVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVV
KKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKV
ELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFE
PLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESL
YQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYIT
PMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWK
QRKNVQNINLFVVDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDV
AHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVI
VFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYL
HEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYP
IYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEI
VTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSK
CISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPI
RHHEDNLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAI
RLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVE
SVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQ
LEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATG
AHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD
NT seq 6411 nt   +upstreamnt  +downstreamnt
atggcggatgtaaccgcccgtagtctgcaatacgagtacaaggcgaactcgaatcttgtg
ctccaagctgaccgttctctcattgaccggacccgccgggatgaacccacaggagaggtg
ctgtcccttgttgggaagctggagggcacccgtatgggagacaaggctcaacggaccaaa
ccgcagatgcaggaggaaagaagagccaagcgaagaaagcgtgatgaggaccggcatgac
atcaacaagatgaagggttatactctgctgtcggagggcattgatgagatggtgggcatc
atctacaagcccaaaactaaagagactcgggagacctatgaggtgctactcagcttcatc
caggctgctcttggggaccagccacgtgatatcctttgtggggcagctgatgaagttcta
gctgttctaaagaatgaaaagctgcgggacaaggaaaggcgaaaggagattgacctgctg
ctgggtcaaacagatgataccagataccatgtgctagtgaacctgggcaaaaagatcaca
gactatggtggagataaggaaatccaaaatatggatgacaacattgatgagacatacggt
gtgaatgtgcagtttgagtctgatgaggaggaaggtgatgaagacgtatacggggaggtt
cgagaagaggcatctgatgatgacatggaaggggacgaggctgtcgtgcgctgcaccctc
tcggctaatctcgtagcctcaggtgaactgatgagttccaagaagaaggatttgcaccct
cgggatattgatgcattttggctgcagcggcagctcagtcgtttctatgatgatgccatc
gtgtcgcagaagaaggcagatgaagtattggagattttgaagacggccagtgatgatcgg
gaatgtgaaaatcagctggttctgctgcttggtttcaacacctttgatttcattaaagtg
ttgcggcagcacaggatgatgattttatactgtaccttgctggccagtgcacaaagtgaa
gctgaaaaggaaaggattatgggaaagatggaagctgacccagagctatccaagttcctc
taccagcttcatgaaaccgagaaggaggatctgatccgagaggaaaggtcccggagagag
cgagtgcgtcagtctcgaatggacacagatctggaaaccatggatctcgaccagggtgga
gaggcactggctccacggcaggttctggacttggaggacctggtttttacccaagggagc
cactttatggccaataaacgctgtcagcttcctgatggatccttccgtcgccagcgtaag
ggctatgaagaggtgcatgtgcctgctctgaagcccaagccctttggctcagaagaacaa
ctgcttccagtggaaaagctgccaaagtatgcccaggctgggtttgagggcttcaaaaca
ctgaatcggatccagagtaagctctaccgtgctgcccttgagacggatgagaatctgctg
ctgtgtgctcctactggtgctgggaagaccaacgtggccctgatgtgcatgctccgagag
attgggaaacacataaacatggacggcaccatcaatgtggatgacttcaagattatctac
attgcccccatgcgctccttggtgcaggagatggtgggcagctttggaaagcgcctggcc
acttatggcatcactgttgctgaactgactggggaccaccagctgtgcaaagaagagatc
agtgccactcagatcatcgtctgcacccccgagaagtgggacatcatcacccgcaagggt
ggtgagcgcacctacacccagctggtgcggctcatcattctggatgagattcatcttctc
cacgatgacagaggtcctgtcttagaagctttagtggccagggccatccgaaacattgag
atgacccaagaggatgtccgactcattggtctcagtgccaccctacccaactatgaagat
gtagccacctttctacgtgttgaccctgccaagggtctcttttactttgacaacagcttc
cgtccagtgcctctggaacagacatatgtgggtatcacagagaaaaaagctatcaagcgt
ttccagatcatgaatgaaatcgtctatgaaaaaatcatggaacatgctggaaaaaatcag
gtgctggtgtttgtccactcccggaaggagactggaaagacagccagggccatccgggac
atgtgcctagaaaaggacactctgggtctgtttctgagggagggctcagcctccacagaa
gtcctgcgaacagaagctgagcagtgcaagaacctagagctgaaggatcttctgccttat
ggctttgctattcatcacgcaggcatgaccagggttgaccgaacactcgtggaggatctt
tttgctgataaacatattcaggttttagtttccacagcaactctagcttggggtgtgaat
ctccctgcacatacagtcatcatcaaaggcacccaggtgtacagtccagagaaggggcgt
tggacagaactgggagcactggacattctgcagatgctgggacgtgccggaagaccccag
tatgacaccaagggtgaaggcatactcatcacatctcatggggagctacagtactacctg
tccctcctcaatcaacaacttcctattgaaagccagatggtttcaaagcttcctgacatg
ctcaatgcagaaatcgtgctaggaaatgtccagaatgccaaggatgcggtgaactggctg
ggctatgcctacctctatatccgaatgctgcgatccccaaccctctatggcatctctcat
gatgacctcaagggagatcccctgctggaccagcgccgactagatctggttcatacagct
gccctgatgctggacaagaacaatctggtcaagtacgacaagaagacgggcaacttccag
gtgacagaactgggccgtatagccagccactactacatcaccaatgatacagtgcagact
tacaaccagctgctgaagcccaccctgagtgagattgagcttttcagggtcttctcattg
tcctctgagttcaagaacatcacagtgagagaggaggagaagctggagctgcagaagttg
ctggagagggtgcctatccctgtaaaggagagcattgaggaacccagtgctaagatcaac
gttcttctgcaagccttcatctcacagctgaaattggagggctttgcactgatggctgac
atggtgtatgtcacacagtcggctggccggttgatgcgagcgatatttgaaattgtcctg
aaccgaggttgggcacagcttacagacaagaccctgaacctctgcaagatgatcgacaaa
cgcatgtggcagtccatgtgtcctctgcgccagttccggaaactccctgaggaagtagtg
aagaagattgagaagaagaatttcccctttgagcgtctgtacgacctgaatcataatgag
attggggagcttatccgcatgccaaagatggggaagaccatccacaaatatgtccatctg
tttcccaagttggagttgtcagtgcacctgcagcctatcacacgctccaccctgaaggtg
gagctgaccatcacgccagacttccagtgggatgaaaaggtgcatggttcatccgaggct
ttttggattctggtggaggatgtggacagcgaggtgattctgcaccatgagtattttctc
ctcaaggccaagtacgcccaggacgagcacctcattacattcttcgtgcctgtctttgaa
ccgctgccccctcagtacttcatccgagtggtgtctgaccgctggctctcttgtgagacc
cagctgcctgtctccttccggcacctgatcttgccggagaagtacccccctccaaccgaa
cttttggacctgcagcccttgcccgtgtctgctctgagaaacagtgcctttgagagtctt
taccaagataaatttcctttcttcaatcccatccagacccaggtgtttaacactgtatac
aacagtgacgacaacgtgtttgtgggggcccccacgggcagcgggaagactatttgtgca
gagtttgccatcctgcgaatgctgctgcagagctcggaggggcgctgtgtgtacatcacc
cccatggaggccctggcagagcaggtatacatggactggtacgagaagttccaggacagg
ctcaacaagaaggtggtactcctgacaggcgagaccagcacagacctgaagctgctgggc
aaagggaacattatcatcagcacccctgagaagtgggacatactttcccggcgatggaag
cagcgcaagaacgtgcagaacatcaacctcttcgtggtggatgaggtccaccttatcggg
ggcgagaatgggcctgtcttagaagtgatctgctcccgaatgcgctacatctcctcccag
attgagcggcccattcgcattgtggcactcagctcttcgctctccaatgccaaggatgtg
gcccactggctgggctgcagtgccacctccaccttcaacttccatcccaatgtgcgtccc
gtccccttggagctgcacatccagggcttcaacatcagccatacacaaacccgcctgctc
tccatggccaagcctgtgtaccatgctatcaccaagcactcgcccaagaagcctgtcatt
gtctttgtgccgtctcgcaagcagacccgcctcactgccattgacatcctcaccacctgt
gcagcagacatccaacggcagaggttcttgcactgcaccgagaaggatctgattccgtac
ctggagaagctaagtgacagcacgctcaaggaaacgctgctaaatggggtgggctacctg
catgaggggctcagccccatggagcgacgcctggtggagcagctcttcagctcaggggct
atccaggtggtggtggcttctcggagtctctgctggggcatgaacgtggctgcccacctg
gtaatcatcatggatacccagtactacaatggcaagatccacgcctatgtggattacccc
atctatgacgtgcttcagatggtgggccacgccaaccgccctttgcaggacgatgagggg
cgctgtgtcatcatgtgtcagggctccaagaaggatttcttcaagaagttcttatatgag
ccattgccagtagaatctcacctggaccactgtatgcatgaccacttcaatgctgagatc
gtcaccaagaccattgagaacaagcaggatgctgtggactacctcacctggacctttctg
taccgccgcatgacacagaaccccaattactacaacctgcagggcatctcccatcgtcac
ttgtcggaccacttgtcagagctggtggagcagaccctgagtgacctggagcagtccaag
tgcatcagcatcgaggacgagatggacgtggcgcctctgaacctaggcatgatcgccgcc
tactattacatcaactacaccaccattgagctcttcagcatgtccctcaatgccaagacc
aaggtgcgagggcttatcgagatcatctccaatgcagcagagtatgagaacattcccatc
cggcaccatgaagacaatctcctgaggcagttggctcagaaggtcccccacaagctgaat
aaccctaagttcaatgatccgcacgtcaagaccaacctgctcctgcaggctcacttgtct
cgcatgcagctgagtgctgagttgcagtcagatacggaggaaatccttagtaaggcaatc
cggctcatccaggcctgcgtggatgtcctttccagcaatgggtggctcagccctgctctg
gcagctatggaactggcccagatggtcacccaagccatgtggtccaaggactcatacctg
aagcagctgccacacttcacctctgagcatatcaaacgttgcacagacaagggagtggag
agtgttttcgacatcatggagatggaggatgaagaacggaacgcgttgcttcagctgact
gacagccagattgcagatgtggctcgcttttgtaaccgctaccctaatatcgaactatct
tatgaggtggtagataaggacagcatccgcagtggcgggccagttgtggtgctggtgcag
ctggagcgagaggaggaagtcacaggccctgtcattgcgcctctcttcccgcagaaacgt
gaagagggctggtgggtggtgattggagatgccaagtccaatagcctcatctccatcaag
aggctgaccttgcagcagaaggccaaggtgaagttggactttgtggccccagccactggt
gcccacaactacactctgtacttcatgagtgacgcttacatgggatgtgaccaggagtac
aaattcagcgtggatgtgaaagaagctgagacagacagtgattcagattga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (47)   
   RefSeq(nuc) (1)   
   GenBank (23)   
   EMBL (23)   
3D Structure (49)   
   PDB (49)   
Protein domain (11)   
   Pfam (11)   
All databases (147)   

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