KEGG   Homo sapiens (human): 23101
Entry
23101             CDS       T01001                                 
Symbol
MCF2L2, ARHGEF22
Name
(RefSeq) MCF.2 cell line derived transforming sequence-like 2
  KO
K20685  guanine nucleotide exchange factor MCF2
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    23101 (MCF2L2)
Membrane trafficking [BR:hsa04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    23101 (MCF2L2)
SSDB
Motif
Pfam: RhoGEF CRAL_TRIO_2 PH Spectrin CRAL_TRIO PH_10
Other DBs
NCBI-GeneID: 23101
NCBI-ProteinID: NP_055893
OMIM: 619946
HGNC: 30319
Ensembl: ENSG00000053524
UniProt: Q86YR7
Position
3:complement(183178041..183428619)
AA seq 1114 aa
MLSCLKEEMPPQELTRRLATVITHVDEIMQQEVRPLMAVEIIEQLHRQFAILSGGRGEDG
APIITFPEFSGFKHIPDEDFLNVMTYLTSIPSVEAASIGFIVVIDRRRDKWSSVKASLTR
IAVAFPGNLQLIFILRPSRFIQRTFTDIGIKYYRNEFKTKVPIIMVNSVSDLHGYIDKSQ
LTRELGGTLEYRHGQWVNHRTAIENFALTLKTTAQMLQTFGSCLATAELPRSMLSTEDLL
MSHTRQRDKLQDELKLLGKQGTTLLSCIQEPATKCPNSKLNLNQLENVTTMERLLVQLDE
TEKAFSHFWSEHHLKLNQCLQLQHFEHDFCKAKLALDNLLEEQAEFTGIGDSVMHVEQIL
KEHKKLEEKSQEPLEKAQLLALVGDQLIQSHHYAADAIRPRCVELRHLCDDFINGNKKKW
DILGKSLEFHRQLDKVSQWCEAGIYLLASQAVDKCQSREGVDIALNDIATFLGTVKEYPL
LSPKEFYNEFELLLTLDAKAKAQKVLQRLDDVQEIFHKRQVSLMKLAAKQTRPVQPVAPH
PESSPKWVSSKTSQPSTSVPLARPLRTSEEPYTETELNSRGKEDDETKFEVKSEEIFESH
HERGNPELEQQARLGDLSPRRRIIRDLLETEEIYIKEIKSIIDGYITPMDFIWLKHLIPD
VLQNNKDFLFGNIRELYEFHNRTFLKELEKCAENPELLAHCFLKRKEDLQIYFKYHKNLP
RARAIWQECQDCAYFGVCQRQLDHNLPLFKYLKGPSQRLIKYQMLLKGLLDFESPEDMEI
DPGELGGSAKDGPKRTKDSAFSTELQQALAVIEDLIKSCELAVDLAAVTECPDDIGKLGK
LLLHGPFSVWTIHKDRYKMKDLIRFKPSQRQIYLFERGIVFCKIRMEPGDQGLSPHYSFK
KTMKLMTLSIRQLGRGSHRKFEIASRNGLEKYILQAASKEIRDCWFSEISKLLMEQQNNI
KDQGNPQFEMSTSKGSGAGSGPWIKNMERATTSKEDPASSTGGIKGCSSREFSSMDTFED
CEGAEDMEKESSALSLAGLFQSDDSHETCSSKSAFLERGESSQGEKEERDEEETATRSTE
EERAGASTGRLAPAGATAGFQARALRPRTSAQES
NT seq 3345 nt   +upstreamnt  +downstreamnt
atgctgtcttgcttaaaagaagagatgcctccccaggagctcacccggcgactggccaca
gtgatcactcatgtcgatgaaattatgcagcaggaagtcagacccctgatggcggtggag
ataatagaacaacttcacagacaatttgccattctttcaggaggccgaggggaggatggc
gcccccatcatcacgttcccagagttttcggggttcaaacacatcccagatgaagacttc
ctgaatgtcatgacctacctgactagcatccccagtgtggaggctgccagcattggattc
attgttgttatcgacagacgaagagacaagtggagctccgtaaaggcatccttgacacga
atagctgtggcatttccaggaaacttacagctcatattcatccttcgtccatctcgcttt
atccagaggacattcactgacattggcattaaatactatcgaaatgagtttaaaacgaaa
gtgccgatcatcatggtaaactctgtctctgaccttcacggctacatcgacaaaagccaa
ctgacccgggaattaggggggactttggaatatcgccacggtcagtgggtaaatcaccgc
actgccatcgaaaactttgccttgaccttgaagaccactgcccagatgctgcagacgttt
gggtcctgcctggccacagcagagctgcccagaagcatgctatccacggaagaccttctc
atgtcccacacaaggcagcgggacaagctgcaggatgagctgaaattacttggaaagcag
gggaccacattgctgtcatgcatccaagaaccagcaaccaaatgtcccaacagcaaactc
aatctcaaccaacttgagaatgtaactaccatggaaaggttattagttcaactggatgaa
acagaaaaagcctttagtcacttttggtctgagcatcatctgaagcttaaccagtgccta
caactacagcattttgagcacgatttttgtaaggctaagcttgccctggataatttgctg
gaagagcaagcagagtttacaggcattggagacagcgtgatgcacgtggagcagattctt
aaggaacacaaaaaactggaggaaaaaagccaggagcccctggaaaaggcccagctgctg
gcactggttggggaccagctcatccaaagccaccattatgcagcagatgccatcaggccc
cggtgtgtggagctcaggcacctctgtgacgatttcatcaatggaaacaagaaaaaatgg
gacattttaggaaagtccttagagtttcatagacagctggacaaggtcagccaatggtgt
gaggcaggaatctacctcttggcttcccaagctgtagacaagtgccagtctcgagaaggg
gttgatatcgccttgaacgacattgcgacattcctgggcacagtcaaggagtacccgttg
ctcagccccaaggagttttacaacgagtttgagttgctgctcaccctcgatgcaaaggcc
aaagcccagaaagttttgcagaggctggatgatgtccaggaaatatttcacaagaggcaa
gtgagtctgatgaaactggcagccaaacagactcgtccagtgcaacctgtggccccacat
cctgagtcttcaccaaaatgggtgtcatcaaaaaccagccagccctccacctcggtccct
ctagctcgtcctctgagaacgtctgaggaaccttatacggagacagagttgaactcccgg
ggaaaggaagatgatgagactaaatttgaagtcaagagtgaagaaatctttgaaagccat
catgaaagggggaaccctgagctggagcagcaggccaggctcggagacctttccccccgc
aggcgcattatacgtgacttgcttgagactgaagagatttacataaaagagattaaaagc
ataattgatggatatatcactccaatggattttatttggctaaagcatctaattccagat
gttcttcagaataacaaggactttctctttgggaatattagagaactttacgaatttcac
aacaggacttttctaaaagagttggaaaagtgtgctgagaaccctgaacttctggcacat
tgctttctcaagagaaaagaagatcttcagatatattttaaataccataagaatctgccc
cgagctagggcaatctggcaagagtgtcaagactgcgcctactttggggtatgccagcgc
caactggatcacaatctccctctttttaagtatctcaaaggaccaagccagagacttata
aaataccagatgctgttgaagggtctgctggatttcgagtctcctgaagatatggagata
gacccaggtgaactaggaggctcggctaaggatgggccaaagagaaccaaagattcagca
ttctcaactgaactacaacaagctttggcagtgatagaggatttgatcaagtcctgtgag
ttggctgtggacctagcagcagtgactgaatgtccggacgatattggaaaactaggcaag
ctgttgctgcacggccctttcagcgtctggacaattcacaaggatcgttataaaatgaag
gatttgattcgatttaaacccagccagaggcaaatctacctatttgaaaggggaatagtg
ttctgtaagatacgaatggagcctggggaccagggattatctcctcattacagcttcaag
aagaccatgaagctgatgacactttcaattcgccagcttggaagggggagccatagaaag
tttgagattgccagtcgaaatggacttgagaaatacatcctgcaggcagcttcaaaagaa
atcagagactgttggttttcagaaataagtaaattattgatggaacaacaaaataatatc
aaagaccaaggaaatccacagtttgaaatgagcacgagcaaaggcagtggagcaggatcc
ggaccatggattaaaaatatggaaagagctaccactagcaaggaagacccggcctccagc
acaggagggattaaaggctgctccagcagggagtttagctccatggacacctttgaagac
tgtgaaggcgcagaagacatggaaaaggagagcagtgctctgagtctcgcgggccttttc
cagtcggacgacagtcacgaaacctgttcctccaaatctgctttcctggagaggggagaa
agcagccagggagaaaaagaagaacgcgatgaggaggaaacggcgacccgcagcaccgag
gaggagcgcgctggggcgtccacgggccggctggctcctgcgggggcgacggctggtttc
caggcgagggcgctgcgcccgaggacctccgcccaggagagctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (15)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (41)   
   RefSeq(nuc) (13)   
   GenBank (14)   
   EMBL (14)   
Protein domain (6)   
   Pfam (6)   
All databases (89)   

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