KEGG   Homo sapiens (human): 23192
Entry
23192             CDS       T01001                                 
Symbol
ATG4B, APG4B, AUTL1, HsAPG4B
Name
(RefSeq) autophagy related 4B cysteine peptidase
  KO
K08342  cysteine protease ATG4 [EC:3.4.22.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04136  Autophagy - other
hsa04140  Autophagy - animal
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06182  Shigella
nt06532  Autophagy
  Element
N00156  Autophagy-vesicle nucleation/elongation/maturation, LC3-II formation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    23192 (ATG4B)
   04136 Autophagy - other
    23192 (ATG4B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    23192 (ATG4B)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    23192 (ATG4B)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    23192 (ATG4B)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C54: Aut2 peptidase family
   23192 (ATG4B)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Autophagosome formation proteins
   Atg8 conjugation proteins
    23192 (ATG4B)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Autophagy-related proteins
    23192 (ATG4B)
SSDB
Motif
Pfam: Peptidase_C54 ATG4_LIR
Other DBs
NCBI-GeneID: 23192
NCBI-ProteinID: NP_037457
OMIM: 611338
HGNC: 20790
Ensembl: ENSG00000168397
UniProt: Q9Y4P1 B3KVU2
Structure
Position
2:241637693..241673857
AA seq 393 aa
MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPA
IGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKD
SYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIR
RLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYV
ETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFH
CQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLA
CPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
NT seq 1182 nt   +upstreamnt  +downstreamnt
atggacgcagctactctgacctacgacactctccggtttgctgagtttgaagattttcct
gagacctcagagcccgtttggatactgggtagaaaatacagcattttcacagaaaaggac
gagatcttgtctgatgtggcatctagactttggtttacatacaggaaaaactttccagcc
attggggggacaggccccacctcggacacaggctggggctgcatgctgcggtgtggacag
atgatctttgcccaagccctggtgtgccggcacctaggccgagattggaggtggacacaa
aggaagaggcagccagacagctacttcagcgtcctcaacgcattcatcgacaggaaggac
agttactactccattcaccagatagcgcaaatgggagttggcgaaggcaagtccataggc
cagtggtacgggcccaacactgtcgcccaggtcctgaagaagcttgctgtcttcgatacg
tggagctccttggcggtccacattgcaatggacaacactgttgtgatggaggaaatcaga
aggttgtgcaggaccagcgttccctgtgcaggcgccactgcgtttcctgcagattccgac
cggcactgcaacggattccctgccggagctgaggtcaccaacaggccgtcgccatggaga
cccctggtacttctcattcccctgcgcctggggctcacggacatcaacgaggcctacgtg
gagacgctgaagcactgcttcatgatgccccagtccctgggcgtcatcggagggaagccc
aacagcgcccactacttcatcggctacgttggtgaggagctcatctacctggacccccac
accacgcagccagccgtggagcccactgatggctgcttcatcccggacgagagcttccac
tgccagcacccgccgtgccgcatgagcatcgcggagcttgacccgtccatcgctgtgggg
tttttctgtaagactgaagatgacttcaatgattggtgccagcaagtcaaaaagctgtct
ctgcttggaggtgccctgcccatgtttgagctggtggagctgcagccttcacatctggcc
tgccccgacgtcctgaacctgtccctagattcttctgatgtagagcgactggaaagattc
ttcgactcagaagatgaagactttgaaatcctgtccctttga

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