KEGG   Homo sapiens (human): 23381
Entry
23381             CDS       T01001                                 
Symbol
SMG5, EST1B, LPTS-RP1, LPTSRP1, SMG-5
Name
(RefSeq) SMG5 nonsense mediated mRNA decay factor
  KO
K11125  protein SMG5
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    23381 (SMG5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    23381 (SMG5)
   03032 DNA replication proteins [BR:hsa03032]
    23381 (SMG5)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Surveillance factors
    Other surveillance factors
     23381 (SMG5)
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     23381 (SMG5)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Termination Factors
   Telomerase complex (animals)
    23381 (SMG5)
SSDB
Motif
Pfam: EST1_DNA_bind EST1 PIN_4
Other DBs
NCBI-GeneID: 23381
NCBI-ProteinID: NP_056142
OMIM: 610962
HGNC: 24644
Ensembl: ENSG00000198952
UniProt: Q9UPR3
Structure
Position
1:complement(156249224..156291516)
AA seq 1016 aa
MSQGPPTGESSEPEAKVLHTKRLYRAVVEAVHRLDLILCNKTAYQEVFKPENISLRNKLR
ELCVKLMFLHPVDYGRKAEELLWRKVYYEVIQLIKTNKKHIHSRSTLECAYRTHLVAGIG
FYQHLLLYIQSHYQLELQCCIDWTHVTDPLIGCKKPVSASGKEMDWAQMACHRCLVYLGD
LSRYQNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLAGSKYYNVEAMYCYLRCIQ
SEVSFEGAYGNLKRLYDKAAKMYHQLKKCETRKLSPGKKRCKDIKRLLVNFMYLQSLLQP
KSSSVDSELTSLCQSVLEDFNLCLFYLPSSPNLSLASEDEEEYESGYAFLPDLLIFQMVI
ICLMCVHSLERAGSKQYSAAIAFTLALFSHLVNHVNIRLQAELEEGENPVPAFQSDGTDE
PESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDLSEGFES
DSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTLE
PPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSNLLLQPTTNPHT
SASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERSIQEKLQVLMAEGLLPAVKV
FLDWLRTNPDLIIVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALCPEVQDLLEGCELP
DLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESVVRICCIRSFGHFIARLQ
GSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMAQEEARRNRLMRDMAQLRLQLEVSQL
EGSLQQPKAQSAMSPYLVPDTQALCHHLPVIRQLATSGRFIVIIPRTVIDGLDLLKKEHP
GARDGIRYLEAEFKKGNRYIRCQKEVGKSFERHKLKRQDADAWTLYKILDSCKQLTLAQG
AGEEDPSGMVTIITGLPLDNPSVLSGPMQAALQAAAHASVDIKNVLDFYKQWKEIG
NT seq 3051 nt   +upstreamnt  +downstreamnt
atgagccaaggcccccccacaggggagagcagcgagcccgaagcaaaagtcctccacact
aagcggctttaccgggctgtggtggaggctgtgcatcgacttgacctcatcctttgcaac
aaaactgcttatcaagaagtattcaaaccagaaaacattagcctgaggaacaagctgcgt
gagctctgcgtcaagcttatgttcctgcacccagtggactatgggagaaaggctgaggag
ctgctgtggagaaaggtatactatgaagttatccagcttatcaagactaacaaaaagcac
atccacagccggagcactttggaatgtgcctacaggacgcacctggttgctggtattggc
ttctaccagcatctccttctctatatccagtcccactaccagctggaactgcagtgctgc
atcgactggacccatgtcactgaccccctcataggatgcaagaagccagtgtctgcctca
gggaaggagatggattgggcacagatggcatgtcaccgatgtctggtgtatctgggggat
ttgtcccgatatcagaatgaattagctggcgtagataccgagctgctagccgagagattt
tactaccaagccctgtcagtagctcctcagattggaatgcccttcaatcagctgggcacc
ctggcaggcagcaagtactataatgtggaagccatgtattgctacctgcgctgcatccag
tcagaagtgtcctttgagggagcctatgggaacctcaagcggctgtatgacaaggcagcc
aaaatgtaccaccaactgaagaagtgtgagactcggaaactgtctcctggcaaaaagcga
tgtaaagacattaaaaggttgctagtgaactttatgtatctgcaaagcctcctacagccc
aaaagcagctccgtggactcagagctgacctcactttgccagtcagtcctggaggacttc
aacctctgcctcttctacctgccctcctcacccaacctcagcctggccagtgaggatgag
gaggagtatgagagtggatatgctttcctcccggaccttctcatctttcaaatggtcatc
atctgccttatgtgtgtgcacagcttggagagagcaggatccaagcagtacagtgcagcc
attgccttcaccctggccctcttttcccacctcgtcaatcatgtcaacatacggctgcag
gctgagctggaagagggcgagaatcccgtcccggcattccagagtgatggcacagatgaa
ccagagtccaaggaacctgtggagaaagaggaggagccagatcctgagcctcctcctgta
acaccccaagtgggtgagggcagaaagagccgtaagttctctcgcctctcctgtctccgc
cgtcgccgccacccacccaaagttggtgatgacagtgacctgagtgaaggctttgaatcg
gactcaagccatgactcagcccgggccagtgagggctcagacagtggctctgacaagagt
cttgaaggtgggggaacggcctttgatgctgaaacagactcggaaatgaatagccaggag
tcccgatcagacttggaagatatggaggaagaggaggggacacggtcaccaaccctggag
ccccctcggggcagatcagaggctcccgattccctcaatggcccactgggccccagtgag
gctagcattgccagcaatctacaagccatgtccacccagatgttccagactaagcgctgc
ttccgactggcccccacctttagcaacctgctcctccagcccaccaccaaccctcatacc
tcggccagccacaggccttgcgtcaatggggatgtagacaagccttcagagccagcctct
gaggagggctctgagtcggaggggagtgagtccagtggacgctcctgtcggaatgagcgc
agcatccaggagaagcttcaggtcctgatggccgaaggtctgcttcctgctgtgaaagtc
ttcctggactggcttcggaccaaccccgacctcatcatcgtgtgtgcgcagagctctcaa
agtctgtggaaccgcctgtctgtgttgctgaatctgttgcctgctgctggtgaactccag
gagtctggcctggccttgtgtcctgaggtccaagatcttcttgaaggttgtgaactgcct
gacctcccctctagccttctgctcccagaggacatggctcttcgtaacctgcccccgctc
cgagctgcccacagacgctttaactttgacacggatcggcccctgctcagcaccttagag
gagtcagtggtgcgcatctgctgcatccgcagctttggtcatttcatcgcccgcctgcaa
ggcagcatcctgcagttcaacccagaggttggcatcttcgtcagcattgcccagtctgag
caggagagcctgctgcagcaggcccaggcacagttccgaatggcacaggaggaagctcgt
cggaacaggctcatgagagacatggctcagctacgacttcagctcgaagtgtctcagctg
gagggcagcctgcagcagcccaaggcccagtcagccatgtctccctacctcgtccctgac
acccaggccctctgccaccatctccctgtcatccgccaactggccaccagtggccgcttc
attgtcatcatcccaaggacagtgatcgatggcctggatttgctgaagaaggaacaccca
ggggcccgggatgggattcggtacctggaggcagagtttaaaaaaggaaacaggtacatt
cgctgccagaaagaggtgggaaagagctttgagcggcataagctgaagaggcaggatgca
gatgcctggactctctataagatcctagacagctgcaaacagctgactctggcccagggg
gcaggtgaggaggatccgagtggcatggtgaccatcatcacaggccttccactggacaac
cccagcgtgctttcaggccccatgcaggcagccctgcaggccgctgcccacgccagtgtg
gacatcaagaatgttctggacttctacaagcagtggaaggaaattggttga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (12)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (33)   
   RefSeq(nuc) (5)   
   GenBank (14)   
   EMBL (14)   
3D Structure (1)   
   PDB (1)   
Protein domain (3)   
   Pfam (3)   
All databases (75)   

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