KEGG   Homo sapiens (human): 23527
Entry
23527             CDS       T01001                                 
Symbol
ACAP2, CENTB2, CNT-B2
Name
(RefSeq) ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
  KO
K12489  Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    23527 (ACAP2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    23527 (ACAP2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    23527 (ACAP2)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Arf GTPases and associated proteins
   Arf associated proteins
    23527 (ACAP2)
 Protein recycling
  Rab GTPases and associated proteins
   Other Rab GTPase associated proteins
    23527 (ACAP2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   23527 (ACAP2)
SSDB
Motif
Pfam: BAR_3 ArfGap PH Ank_2 Ank Ank_4 Ank_5 Ank_3 PH_8 PH_11
Other DBs
NCBI-GeneID: 23527
NCBI-ProteinID: NP_036419
OMIM: 607766
HGNC: 16469
Ensembl: ENSG00000114331
UniProt: Q15057
Structure
Position
3:complement(195274745..195443020)
AA seq 778 aa
MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKF
KDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVL
QSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQ
KHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQK
KFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSI
ATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLA
DPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYE
ANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLS
ISKFGPGDQVRASAQSSVRSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQDSSMFLD
SKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFL
LQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANA
DIVTLLRLARMNEEMRESEGLYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF
NT seq 2337 nt   +upstreamnt  +downstreamnt
atgaagatgactgtggatttcgaggagtgtctgaaggactcgccccgcttcagggcagct
ttggaagaagtagaaggtgatgtggcagaattggaactaaaacttgataagcttgtgaaa
ctttgtattgcaatgattgatactggaaaagccttttgtgttgcaaataaacagttcatg
aatgggattcgagacctggctcagtattctagtaatgatgctgtcgttgagacaagtttg
accaagttttctgacagtcttcaagaaatgataaattttcacacaatcctgtttgaccaa
actcagagatcaattaaggcacagcttcagaactttgttaaagaagatcttagaaaattc
aaagatgccaagaagcaattcgaaaaagtcagtgaagaaaaagaaaatgcgttagtaaaa
aatgcccaagtacaaagaaacaaacaacatgaagttgaagaagccaccaacattctgaca
gcaacaagaaaatgtttccgacacatagccctcgattatgtgcttcagattaatgttctt
caatcaaaaaggagatcagaaatcctaaaatcaatgttgtcatttatgtatgcccatttg
gccttctttcatcaaggatatgatctgtttagtgaacttggaccctacatgaaggatctt
ggtgcacagttggatcgactggttgtggatgcagcaaaggagaaaagagaaatggagcaa
aaacattccaccattcaacaaaaggatttctccagtgatgattctaagttagaatataac
gtagatgctgcaaatggcatagttatggaaggatatctgttcaaacgagccagcaatgcc
ttcaaaacttggaacaggcgctggttttcaatacagaataatcagttggtttaccagaaa
aaatttaaggataatccgactgtggtagttgaagacctcaggctttgcacagtgaaacat
tgtgaagacatagagcgacgattctgctttgaggtggtctcgccaacaaaaagttgcatg
ctccaggcagattccgaaaagctgcgccaggcatggattaaggctgttcagaccagtatt
gctactgcttatagagagaagggtgatgaatcagagaagctggataagaaatcatctcca
tccacaggaagcctagattctggaaatgagtccaaagagaaattattgaaaggagaaagt
gcgcttcagcgggtccagtgtatccctggcaatgccagctgttgtgactgtggcctggca
gatccacggtgggccagcatcaacctgggcatcaccttgtgtatcgagtgctccggaatt
caccggagccttggggttcatttttcaaaagtacgatctttaactttagacacctgggag
ccagaacttttaaagcttatgtgtgagttggggaatgatgttataaatcgagtttatgaa
gctaatgtggaaaaaatgggaataaagaaaccccaaccaggacaaagacaggagaaggag
gcatatatcagagcaaaatatgtggagaggaaatttgtggataaatattctatatcatta
tcacctcctgagcagcaaaaaaagtttgtctctaaaagttctgaagaaaagaggctgagc
atttctaaatttgggccaggggaccaagtcagagcatctgcccaaagttcagtcagaagt
aatgacagtggaattcagcagagctctgatgatggaagagaatctttaccctccacggtg
tcagccaatagtttatatgagcctgaaggagaaaggcaagattcttctatgtttcttgac
tcgaaacatcttaatccaggacttcagctttatagggcgtcatatgaaaaaaaccttcct
aaaatggctgaggctttggctcatggtgcagacgtgaactgggccaattcagaggaaaac
aaagcgacaccacttattcaggctgtattagggggctctttggtgacgtgtgagttcctc
ctacagaatggtgctaatgtcaaccaaagagatgtccaagggcggggaccattgcaccat
gccaccgtcttagggcacacagggcaggtatgtttattcctaaaacgaggtgccaatcaa
catgccactgatgaagaagggaaagaccctttgagcatagctgtggaagcagccaatgct
gatatagtcaccttgttacgtttagcaagaatgaatgaagagatgcgggaatcagaagga
ctttatggacagccaggtgatgaaacttatcaggacatatttcgtgatttttcccaaatg
gcatccaataatccagagaaactaaatcgtttccagcaagattcacagaaattctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (27)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (25)   
DNA sequence (51)   
   RefSeq(nuc) (25)   
   GenBank (13)   
   EMBL (13)   
3D Structure (1)   
   PDB (1)   
Protein domain (10)   
   Pfam (10)   
All databases (113)   

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