KEGG   Homo sapiens (human): 23569
Entry
23569             CDS       T01001                                 
Symbol
PADI4, PAD, PAD4, PADI5, PDI4, PDI5
Name
(RefSeq) peptidyl arginine deiminase 4
  KO
K24669  protein-arginine deiminase 4 [EC:3.5.3.15]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04613  Neutrophil extracellular trap formation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    23569 (PADI4)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.3  In linear amidines
    3.5.3.15  protein-arginine deiminase
     23569 (PADI4)
SSDB
Motif
Pfam: PAD PAD_M PAD_N
Other DBs
NCBI-GeneID: 23569
NCBI-ProteinID: NP_036519
OMIM: 605347
HGNC: 18368
Ensembl: ENSG00000159339
UniProt: Q9UM07
Structure
Position
1:17308197..17364004
AA seq 663 aa
MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK
KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCAD
ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM
SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV
PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP
NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP
HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG
KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP
APDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNS
FVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPK
PFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWN
MVP
NT seq 1992 nt   +upstreamnt  +downstreamnt
atggcccaggggacattgatccgtgtgaccccagagcagcccacccatgccgtgtgtgtg
ctgggcaccttgactcagcttgacatctgcagctctgcccctgaggactgcacgtccttc
agcatcaacgcctccccaggggtggtcgtggatattgcccacggccctccagccaagaag
aaatccacaggttcctccacatggcccctggaccctggggtagaggtgaccctgacgatg
aaagtggccagtggtagcacaggcgaccagaaggttcagatttcatactacggacccaag
actccaccagtcaaagctctactctacctcaccggggtggaaatctccttgtgcgcagac
atcacccgcaccggcaaagtgaagccaaccagagctgtgaaagatcagaggacctggacc
tggggcccttgtggacagggtgccatcctgctggtgaactgtgacagagacaatctcgaa
tcttctgccatggactgcgaggatgatgaagtgcttgacagcgaagacctgcaggacatg
tcgctgatgaccctgagcacgaagacccccaaggacttcttcacaaaccatacactggtg
ctccacgtggccaggtctgagatggacaaagtgagggtgtttcaggccacacggggcaaa
ctgtcctccaagtgcagcgtagtcttgggtcccaagtggccctctcactacctgatggtc
cccggtggaaagcacaacatggacttctacgtggaggccctcgctttcccggacaccgac
ttcccggggctcattaccctcaccatctccctgctggacacgtccaacctggagctcccc
gaggctgtggtgttccaagacagcgtggtcttccgcgtggcgccctggatcatgaccccc
aacacccagcccccgcaggaggtgtacgcgtgcagtatttttgaaaatgaggacttcctg
aagtcagtgactactctggccatgaaagccaagtgcaagctgaccatctgccctgaggag
gagaacatggatgaccagtggatgcaggatgaaatggagatcggctacatccaagcccca
cacaaaacgctgcccgtggtcttcgactctccaaggaacagaggcctgaaggagtttccc
atcaaacgcgtgatgggtccagattttggctatgtaactcgagggccccaaacagggggt
atcagtggactggactcctttgggaacctggaagtgagccccccagtcacagtcaggggc
aaggaatacccgctgggcaggattctcttcggggacagctgttatcccagcaatgacagc
cggcagatgcaccaggccctgcaggacttcctcagtgcccagcaggtgcaggcccctgtg
aagctctattctgactggctgtccgtgggccacgtggacgagttcctgagctttgtgcca
gcacccgacaggaagggcttccggctgctcctggccagccccaggtcctgctacaaactg
ttccaggagcagcagaatgagggccacggggaggccctgctgttcgaagggatcaagaaa
aaaaaacagcagaaaataaagaacattctgtcaaacaagacattgagagaacataattca
tttgtggagagatgcatcgactggaaccgcgagctgctgaagcgggagctgggcctggcc
gagagtgacatcattgacatcccgcagctcttcaagctcaaagagttctctaaggcggaa
gcttttttccccaacatggtgaacatgctggtgctagggaagcacctgggcatccccaag
cccttcgggcccgtcatcaacggccgctgctgcctggaggagaaggtgtgttccctgctg
gagccactgggcctccagtgcaccttcatcaacgacttcttcacctaccacatcaggcat
ggggaggtgcactgcggcaccaacgtgcgcagaaagcccttctccttcaagtggtggaac
atggtgccctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (26)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (36)   
   RefSeq(nuc) (24)   
   GenBank (6)   
   EMBL (6)   
3D Structure (19)   
   PDB (19)   
Protein domain (3)   
   Pfam (3)   
All databases (104)   

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