KEGG   Homo sapiens (human): 2531
Entry
2531              CDS       T01001                                 
Symbol
KDSR, DHSR, EKVP4, FVT1, SDR35C1
Name
(RefSeq) 3-ketodihydrosphingosine reductase
  KO
K04708  3-dehydrosphinganine reductase [EC:1.1.1.102]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00600  Sphingolipid metabolism
hsa01100  Metabolic pathways
Module
hsa_M00094  Ceramide biosynthesis
hsa_M00099  Sphingosine biosynthesis
Disease
H00710  Erythrokeratodermia variabilis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    2531 (KDSR)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.102  3-dehydrosphinganine reductase
     2531 (KDSR)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR NAD_binding_10 Polysacc_synt_2 THF_DHG_CYH_C ATP_bind_2
Other DBs
NCBI-GeneID: 2531
NCBI-ProteinID: NP_002026
OMIM: 136440
HGNC: 4021
Ensembl: ENSG00000119537
UniProt: Q06136
Position
18:complement(63327726..63367206)
AA seq 332 aa
MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFIT
LVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVN
CAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGL
FGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISE
TTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLF
RTIALFYLGSFDSIVRRCMMQREKSENADKTA
NT seq 999 nt   +upstreamnt  +downstreamnt
atgctgctgctggctgccgccttcctcgtggccttcgtgctgctgctgtacatggtgtct
ccgctcatcagccccaagcccctcgccctgcccggggcgcatgtggtggttacaggaggt
tccagtggcatcgggaagtgcattgctatcgagtgctataaacaaggagcttttataact
ctggttgcacgaaatgaggataagctgctgcaggcaaagaaagaaattgaaatgcactct
attaatgacaaacaggtggtgctttgcatatcagttgatgtatctcaagactataaccaa
gtagagaatgtcataaaacaagcacaggagaaactgggtccagtggacatgctggtaaat
tgtgcaggaatggcagtgtcaggaaaatttgaagatcttgaagttagtacctttgaaagg
ttaatgagcatcaattacctgggcagcgtgtaccccagccgggccgtgatcaccaccatg
aaggagcgccgggtgggcaggatcgtgtttgtgtcctcccaggcaggacagttgggatta
ttcggtttcacagcctactctgcatccaagtttgccataaggggattggcagaagctttg
cagatggaggtgaagccatataatgtctacatcacagttgcttacccaccagacacagac
acacctggctttgccgaagaaaacagaacaaagcctttggagactcgacttatttcagag
accacatctgtgtgcaaaccagaacaggtggccaaacaaattgttaaagatgccatacaa
ggaaatttcaacagttcccttggctcagatgggtacatgctctcggccctgacctgtggg
atggctccagtaacttctattactgaggggctccagcaggtggtcaccatgggccttttc
cgcactattgctttgttttaccttggaagttttgacagcatagttcgtcgctgcatgatg
cagagagaaaaatctgaaaatgcagacaaaactgcctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (2)   
   KEGG MODULE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
Protein domain (7)   
   Pfam (7)   
All databases (61)   

Download RDF
DBGET integrated database retrieval system