KEGG   Homo sapiens (human): 26052
Entry
26052             CDS       T01001                                 
Symbol
DNM3, Dyna_III
Name
(RefSeq) dynamin 3
  KO
K01528  dynamin 1/3 [EC:3.6.5.5]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04072  Phospholipase D signaling pathway
hsa04144  Endocytosis
hsa04721  Synaptic vesicle cycle
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa05100  Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    26052 (DNM3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    26052 (DNM3)
 09150 Organismal Systems
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    26052 (DNM3)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    26052 (DNM3)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    26052 (DNM3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    26052 (DNM3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    26052 (DNM3)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.5  Acting on GTP to facilitate cellular and subcellular movement
    3.6.5.5  dynamin GTPase
     26052 (DNM3)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Dynamin
    26052 (DNM3)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    26052 (DNM3)
   RhoA-dependent endocytosis
    26052 (DNM3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   26052 (DNM3)
SSDB
Motif
Pfam: Dynamin_M Dynamin_N GED PH MMR_HSR1 TetR_C_27
Other DBs
NCBI-GeneID: 26052
NCBI-ProteinID: NP_056384
OMIM: 611445
HGNC: 29125
Ensembl: ENSG00000197959
UniProt: Q9UQ16
Structure
Position
1:171841498..172418466
AA seq 863 aa
MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG
SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK
DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL
QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA
KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL
KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID
IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFV
LTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLE
LACDSQEDVDSWKASLLRAGVYPDKSVGNNKAENDENGQAENFSMDPQLERQVETIRNLV
DSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRD
EMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPL
ARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVP
SRRPPPSPTRPTIIRPLESSLLD
NT seq 2592 nt   +upstreamnt  +downstreamnt
atggggaaccgggagatggaggagctgatcccgctggtgaaccgtctgcaggacgcgttt
tcggcgctgggacagagctgcctgctggagctgccgcagatcgccgtggtgggcggccag
agcgccggcaagagctcggtgctcgagaacttcgtgggcagggactttctccctcgaggg
tcgggcattgtaacaagacgacctcttgtgctgcagcttgttacttctaaagcagaatat
gccgagtttctacattgcaaaggaaagaaatttacagattttgatgaagttcgccttgag
attgaagcagaaacagatcgcgtgactggaatgaataaaggcatttcctccatacccatt
aatttacgagtctattccccacacgtgttaaatctaacccttattgatctacctggaata
actaaagtgcctgtgggagatcagccaccagatatcgagtatcagatcagagaaatgatt
atgcagttcatcacgagggagaactgtctgattttagctgttactccagccaacactgat
cttgcaaactcagatgcgctgaagctagctaaagaagttgatcctcaaggtctgagaacc
attggagttatcaccaaactggaccttatggatgaaggaacggatgccagggatgttcta
gagaacaaactgttgcctcttcgcaggggttacgtgggggtggtaaacagaagccagaag
gacatagatgggaagaaggacataaaggcagccatgctggcagagaggaagtttttcctt
tcccacccggcttacagacatatcgctgaccgaatgggaaccccacacctgcagaaggtc
cttaatcagcaacttaccaaccacattcgggataccctaccaaacttcaggaacaaacta
cagggacagttgctctccatagaacatgaagtagaagcctacaaaaatttcaaaccagaa
gacccaacaaggaagaccaaagcattgctgcagatggttcagcaatttgctgtggacttt
gagaagagaattgaagggtcaggggatcaagtagataccctggaactctcaggtggtgct
aaaatcaatcgtatttttcatgaacgctttccttttgagatagtaaagatggagttcaat
gagaaagaattgcgaagagaaataagctatgcaatcaaaaacatacatggtatcaggaca
gggttgtttactccagacatggcatttgaagcgatagtcaagaaacagattgtaaagttg
aaagggccttccttgaagagtgtggatctggtaatacaagaattaatcaacactgtgaag
aagtgtaccaaaaaactggcaaacttccccagactctgcgaggaaacggaaaggattgtt
gctaaccacattcgtgagcgagaagggaagacaaaggaccaggtattgctattgattgac
attcaagtctcttacatcaacaccaaccatgaagacttcattggcttcgcaaatgctcag
cagaggagcagtcaggttcacaagaaaaccacagttggaaatcaggtgattcgcaagggg
tggctcaccatcagcaacattggcatcatgaaaggcggctcgaagggatactggttcgtc
cttactgcggaaagcttgtcctggtataaagatgatgaggaaaaagaaaagaagtacatg
cttcccttggacaacctgaaagttcgggatgtggaaaagagctttatgtctagcaagcac
atctttgcactctttaatacagagcaaaggaatgtatacaaagactatcgcttccttgag
ctggcatgtgattcccaggaggatgtcgacagctggaaggcatctctactaagagctggg
gtctatcctgacaaatctgtagggaacaacaaagctgaaaatgatgagaatggacaagca
gaaaacttttccatggacccacaattggagaggcaagtggagaccattcgcaacctcgta
gactcctacatgtccattatcaacaaatgtatccgagatctaattccaaaaacaataatg
caccttatgatcaataacgttaaagatttcataaattccgagctcctagcacagttgtat
tcttcagaggaccaaaataccctgatggaggaatctgctgagcaggctcagcgccgggat
gagatgcttcgaatgtatcaagcactgaaagaagcccttgggataattggggacatcagc
acagccaccgtgtccactccggcaccccctccagtggatgactcctggatacagcactct
cgcaggtcacctcctccaagccccacaacccaaaggaggccaacactaagtgctcccctc
gcaaggcccacatccggccgaggaccagctcctgccattccctctcctggcccccactct
ggggctcctccagtcccattccgtccaggcccattacctcctttccccagcagcagtgac
tccttcggagcccctccacaagttccatctaggcctacgagggccccgcccagtgtccca
agccggagaccacccccatcaccaactcgtcccactataatccgcccactagaatcctcc
ctgttagactaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (5)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (46)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (44)   
DNA sequence (71)   
   RefSeq(nuc) (45)   
   GenBank (13)   
   EMBL (13)   
3D Structure (2)   
   PDB (2)   
Protein domain (6)   
   Pfam (6)   
All databases (162)   

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