KEGG   Homo sapiens (human): 27235
Entry
27235             CDS       T01001                                 
Symbol
COQ2, CL640, COQ10D1, MSA1, PHB:PPT
Name
(RefSeq) coenzyme Q2, polyprenyltransferase
  KO
K06125  4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00130  Ubiquinone and other terpenoid-quinone biosynthesis
hsa01100  Metabolic pathways
hsa01240  Biosynthesis of cofactors
Module
hsa_M00128  Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol
Disease
H00999  Coenzyme Q10 deficiency
H01614  Multiple system atrophy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    27235 (COQ2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases [BR:hsa01006]
    27235 (COQ2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.39  4-hydroxybenzoate polyprenyltransferase
     27235 (COQ2)
Prenyltransferases [BR:hsa01006]
 Compound prenylation
  4HB prenyltransferase
   27235 (COQ2)
SSDB
Motif
Pfam: UbiA
Other DBs
NCBI-GeneID: 27235
NCBI-ProteinID: NP_056512
OMIM: 609825
HGNC: 25223
Ensembl: ENSG00000173085
UniProt: Q96H96
Position
4:complement(83263824..83285134)
AA seq 421 aa
MTPISQVRMRKGSAHTAAQPGRLGLHPAGATAHACRGMTSIRARPGLTSAMLGSRAAGFA
RGLRAVALAWLPGWRGRSFALARAAGAPHGGDLQPPACPEPRGRQLSLSAAAVVDSAPRP
LQPYLRLMRLDKPIGTWLLYLPCTWSIGLAAEPGCFPDWYMLSLFGTGAILMRGAGCTIN
DMWDQDYDKKVTRTANRPIAAGDISTFQSFVFLGGQLTLALGVLLCLNYYSIALGAGSLL
LVITYPLMKRISYWPQLALGLTFNWGALLGWSAIKGSCDPSVCLPLYFSGVMWTLIYDTI
YAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAMLGALSLVGVNSGQTAPYYAALGAV
GAHLTHQIYTLDIHRPEDCWNKFISNRTLGLIVFLGIVLGNLWKEKKTDKTKKGIENKIE
N
NT seq 1266 nt   +upstreamnt  +downstreamnt
atgaccccaatttcacaagtaaggatgaggaaaggttctgcccacaccgccgcccagcct
ggcagactaggattgcatcctgcgggtgccactgcgcatgcctgccggggaatgacgtca
atccgagctcgtcccggcctcaccagcgccatgctgggctcgcgagccgcggggttcgcg
cggggcctgcgggctgtggcactggcgtggctgccgggctggcggggccgctccttcgcc
ctggcgcgtgcggcaggcgcgccccacggtggtgacttgcagccccccgcctgtcccgag
ccgcgcgggcgccagctcagtttgtccgcggcggcggtggtggactctgcgccccgcccc
ctgcagccgtacttgcgcctcatgcggttggacaagcccattggaacctggcttctgtat
ttaccatgtacctggagcattggtttggcagctgaaccaggttgttttccagattggtac
atgctctccctctttggcactggagctattctgatgcgtggagcaggctgtactattaat
gacatgtgggaccaggactatgataaaaaggttacaagaacagccaatcgtccaatagcc
gctggagacatttcaacttttcagtcctttgtttttcttgggggacagctaaccctggca
ctgggtgttcttctgtgtctaaattactacagtatagctctgggagcaggatccttactt
cttgtcatcacctacccactaatgaaaagaatttcatactggcctcaactagccttgggc
ttgacatttaattggggagcgttacttggatggtctgctatcaagggttcctgtgatcca
tctgtttgcctgcctctttatttttctggagttatgtggacactaatatatgatactatt
tatgcccatcaggacaaaagagatgatgttttgattggtcttaagtcaacggctctgcgg
ttcggagaaaataccaagccgtggctcagcggcttcagtgttgcaatgctgggggcactg
agcctagtgggtgtgaacagtggacagactgctccctactacgctgccctgggtgctgta
ggagcccatctgactcaccagatttacactctagacatccacagacctgaggattgttgg
aataaatttatctccaaccgaacactgggactaatagtttttttagggattgtccttggg
aatttgtggaaagaaaagaagacagacaaaacaaagaagggtatagagaataaaatagaa
aattaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (30)   
   RefSeq(nuc) (2)   
   GenBank (14)   
   EMBL (14)   
Protein domain (1)   
   Pfam (1)   
All databases (80)   

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