KEGG   Homo sapiens (human): 27339
Entry
27339             CDS       T01001                                 
Symbol
PRPF19, NMP200, PRP19, PSO4, SNEV, UBOX4, hPSO4
Name
(RefSeq) pre-mRNA processing factor 19
  KO
K10599  pre-mRNA-processing factor 19 [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
hsa04120  Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    27339 (PRPF19)
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    27339 (PRPF19)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    27339 (PRPF19)
   04121 Ubiquitin system [BR:hsa04121]
    27339 (PRPF19)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    27339 (PRPF19)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     27339 (PRPF19)
Spliceosome [BR:hsa03041]
 Complex B
  Other components
   Prp19 complex
    27339 (PRPF19)
 Complex C
   Prp19-CDC5 complex
    27339 (PRPF19)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  U-box type E3
   27339 (PRPF19)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  Other factors with a suspected DNA repair function
   PSO4 complex
    27339 (PRPF19)
SSDB
Motif
Pfam: WD40 Prp19 ANAPC4_WD40 NBCH_WD40 U-box PROPPIN eIF2A Cytochrom_D1 RMC1_N Nup160 zf-Nse DUF1830 ATG16 Cep57_MT_bd
Other DBs
NCBI-GeneID: 27339
NCBI-ProteinID: NP_055317
OMIM: 608330
HGNC: 17896
Ensembl: ENSG00000110107
UniProt: Q9UMS4
Structure
Position
11:complement(60890547..60906585)
AA seq 504 aa
MSLICSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHP
IRPKPPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARL
TKEVTAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKLQDKA
TVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTG
GADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQ
VVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHP
DGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWD
LRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLTTG
VAFGHHAKFIASTGMDRSLKFYSL
NT seq 1515 nt   +upstreamnt  +downstreamnt
atgtccctaatctgctccatctctaacgaagtgccggagcacccatgtgtatcccctgtc
tctaatcatgtttatgagcggcggctcatcgagaagtacattgcggagaatggtaccgac
cccatcaacaaccagcctctctccgaggagcagctcatcgacatcaaagttgctcaccca
atccggcccaagcctccctcagccaccagcatcccggccattctgaaagctttgcaggat
gagtgggatgcagtcatgctgcacagcttcactctgcgccagcagctgcagacaacccgc
caagagctgtcacacgctctgtaccagcacgatgccgcctgccgtgtcattgcccgtctc
accaaggaagtcactgctgcccgagaagctctggctaccctgaaaccacaggctggcctc
attgtgccccaggctgtgccaagttcccaaccaagtgttgtgggtgcgggtgagccaatg
gatttgggtgagctggtgggaatgaccccagagattattcagaagcttcaagacaaagcc
actgtgctaaccacggagcgcaagaagagagggaagactgtgcctgaggagctggtgaag
ccagaagagctcagcaaataccggcaggtggcatcccacgtggggttgcacagtgccagc
attcctgggatcctggccctggacctctgcccgtccgacaccaacaagatcctcactggt
ggggcggataaaaatgtcgttgtgtttgacaaaagttctgaacaaatcctggctaccctc
aaaggccataccaagaaggtcaccagcgtggtgtttcacccttcccaggacctggtgttt
tctgcttcccccgatgccactatcaggatttggtcggtccccaatgcctcttgtgtacag
gtggttcgggcccatgagagtgctgtgacaggcctcagccttcatgccactggcgactat
ctcctgagctcctccgatgatcagtactgggctttctctgacatccagacagggcgtgtg
ctcaccaaggtgacagatgagacctccggctgctctctcacctgtgcacagttccaccct
gacggactcatctttggaacaggaaccatggactctcagatcaagatctgggacttgaag
gaacgtactaatgtggccaacttccctggccactcgggccccatcactagcatcgccttc
tctgagaatggttactacctggctacagcggctgatgactcctctgtcaagctctgggat
ctgcgcaagcttaagaactttaagactttgcagctggataacaactttgaggtaaagtca
ctgatctttgaccagagtggtacctacctggctcttgggggcacggatgtccagatctac
atctgcaaacaatggacggagattcttcactttacagagcatagcggcctgaccacaggg
gtggccttcgggcatcacgccaagttcatcgcttcaacaggcatggacagaagcctcaag
ttctacagcctgtag

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (15)   
   RefSeq(nuc) (1)   
   GenBank (7)   
   EMBL (7)   
3D Structure (17)   
   PDB (17)   
Protein domain (14)   
   Pfam (14)   
All databases (80)   

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