KEGG   Homo sapiens (human): 3799
Entry
3799              CDS       T01001                                 
Symbol
KIF5B, HEL-S-61, KINH, KNS, KNS1, UKHC
Name
(RefSeq) kinesin family member 5B
  KO
K10396  kinesin family member 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04728  Dopaminergic synapse
hsa04814  Motor proteins
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05132  Salmonella infection
hsa05223  Non-small cell lung cancer
Network
nt06181  Salmonella
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06465  Prion disease
nt06466  Pathways of neurodegeneration
  Element
N00978  Anterograde axonal transport
N00979  Mutation-caused aberrant Htt to anterograde axonal transport
N01017  Mutation-caused aberrant PSEN1 to anterograde axonal transport
N01055  Mutation-caused aberrant SNCA to anterograde axonal transport
N01202  Oligomeric conformation PrPc to anterograde axonal transport
N01297  Arl8-regulated microtubule plus-end directed transport
N01298  Salmonella SifA to microtubule plus-end directed transport
N01299  Salmonella PipB2 to microtubule plus-end directed transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    3799 (KIF5B)
  09142 Cell motility
   04814 Motor proteins
    3799 (KIF5B)
 09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    3799 (KIF5B)
 09160 Human Diseases
  09162 Cancer: specific types
   05223 Non-small cell lung cancer
    3799 (KIF5B)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    3799 (KIF5B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    3799 (KIF5B)
   05012 Parkinson disease
    3799 (KIF5B)
   05014 Amyotrophic lateral sclerosis
    3799 (KIF5B)
   05016 Huntington disease
    3799 (KIF5B)
   05020 Prion disease
    3799 (KIF5B)
   05022 Pathways of neurodegeneration - multiple diseases
    3799 (KIF5B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    3799 (KIF5B)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    3799 (KIF5B)
   04147 Exosome [BR:hsa04147]
    3799 (KIF5B)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Others
    3799 (KIF5B)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Kinesins
     3799 (KIF5B)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   3799 (KIF5B)
SSDB
Motif
Pfam: Kinesin Microtub_bd ATG16
Other DBs
NCBI-GeneID: 3799
NCBI-ProteinID: NP_004512
OMIM: 602809
HGNC: 6324
Ensembl: ENSG00000170759
UniProt: P33176 Q6P164 V9HW29
Structure
Position
10:complement(32009015..32056425)
AA seq 963 aa
MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQ
VYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIY
SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM
DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSK
TGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTTIVI
CCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW
LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRK
CEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAE
NDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL
KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSE
VKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQL
EESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLR
DEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQ
DLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLE
QLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVD
RIKEAVRSKNMARRGHSAQIAKPIRPGQHPAASPTHPSAIRGGGAFVQNSQPVAVRGGGG
KQV
NT seq 2892 nt   +upstreamnt  +downstreamnt
atggcggacctggccgagtgcaacatcaaagtgatgtgtcgcttcagacctctcaacgag
tctgaagtgaaccgcggcgacaagtacatcgccaagtttcagggagaagacacggtcgtg
atcgcgtccaagccttatgcatttgatcgggtgttccagtcaagcacatctcaagagcaa
gtgtataatgactgtgcaaagaagattgttaaagatgtacttgaaggatataatggaaca
atatttgcatatggacaaacatcctctgggaagacacacacaatggagggtaaacttcat
gatccagaaggcatgggaattattccaagaatagtgcaagatatttttaattatatttac
tccatggatgaaaatttggaatttcatattaaggtttcatattttgaaatatatttggat
aagataagggacctgttagatgtttcaaagaccaacctttcagttcatgaagacaaaaac
cgagttccctatgtaaaggggtgcacagagcgttttgtatgtagtccagatgaagttatg
gataccatagatgaaggaaaatccaacagacatgtagcagttacaaatatgaatgaacat
agctctaggagtcacagtatatttcttattaatgtcaaacaagagaacacacaaacggaa
caaaagctgagtggaaaactttatctggttgatttagctggtagtgaaaaggttagtaaa
actggagctgaaggtgctgtgctggatgaagctaaaaacatcaacaagtcactttctgct
cttggaaatgttatttctgctttggctgagggtagtacatatgttccatatcgagatagt
aaaatgacaagaatccttcaagattcattaggtggcaactgtagaaccactattgtaatt
tgctgctctccatcatcatacaatgagtctgaaacaaaatctacactcttatttggccaa
agggccaaaacaattaagaacacagtttgtgtcaatgtggagttaactgcagaacagtgg
aaaaagaagtatgaaaaagaaaaagaaaaaaataagatcctgcggaacactattcagtgg
cttgaaaatgagctcaacagatggcgtaatggggagacggtgcctattgatgaacagttt
gacaaagagaaagccaacttggaagctttcacagtggataaagatattactcttaccaat
gataaaccagcaaccgcaattggagttataggaaattttactgatgctgaaagaagaaag
tgtgaagaagaaattgctaaattatacaaacagcttgatgacaaggatgaagaaattaac
cagcaaagtcaactggtagagaaactgaagacgcaaatgttggatcaggaggagcttttg
gcatctaccagaagggatcaagacaatatgcaagctgagctgaatcgccttcaagcagaa
aatgatgcctctaaagaagaagtgaaagaagttttacaggccctagaagaacttgctgtc
aattatgatcagaagtctcaggaagttgaagacaaaactaaggaatatgaattgcttagt
gatgaattgaatcagaaatcggcaactttagcgagtatagatgctgagcttcagaaactt
aaggaaatgaccaaccaccagaaaaaacgagcagctgagatgatggcatctttactaaaa
gaccttgcagaaataggaattgctgtgggaaataatgatgtaaagcagcctgagggaact
ggcatgatagatgaagagttcactgttgcaagactctacattagcaaaatgaagtcagaa
gtaaaaaccatggtgaaacgttgcaagcagttagaaagcacacaaactgagagcaacaaa
aaaatggaagaaaatgaaaaggagttagcagcatgtcagcttcgtatctctcaacatgaa
gccaaaatcaagtcattgactgaataccttcaaaatgtggaacaaaagaaaagacagttg
gaggaatctgtcgatgccctcagtgaagaactagtccagcttcgagcacaagagaaagtc
catgaaatggaaaaggagcacttaaataaggttcagactgcaaatgaagttaagcaagct
gttgaacagcagatccagagccatagagaaactcatcaaaaacagatcagtagtttgaga
gatgaagtagaagcaaaagcaaaacttattactgatcttcaagaccaaaaccagaaaatg
atgttagagcaggaacgtctaagagtagaacatgagaagttgaaagccacagatcaggaa
aagagcagaaaactacatgaacttacggttatgcaagatagacgagaacaagcaagacaa
gacttgaagggtttggaagagacagtggcaaaagaacttcagactttacacaacctgcgc
aaactctttgttcaggacctggctacaagagttaaaaagagtgctgagattgattctgat
gacaccggaggcagcgctgctcagaagcaaaaaatctcctttcttgaaaataatcttgaa
cagctcactaaagtgcacaaacagttggtacgtgataatgcagatctccgctgtgaactt
cctaagttggaaaagcgacttcgagctacagctgagagagtgaaagctttggaatcagca
ctgaaagaagctaaagaaaatgcatctcgtgatcgcaaacgctatcagcaagaagtagat
cgcataaaggaagcagtcaggtcaaagaatatggccagaagagggcattctgcacagatt
gctaaacctattcgtcccgggcaacatccagcagcttctccaactcacccaagtgcaatt
cgtggaggaggtgcatttgttcagaacagccagccagtggcagtgcgaggtggaggaggc
aaacaagtgtaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (11)   
   KEGG PATHWAY (11)   
Network (14)   
   KEGG NETWORK (14)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (9)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (33)   
   RefSeq(nuc) (5)   
   GenBank (14)   
   EMBL (14)   
3D Structure (20)   
   PDB (20)   
Protein domain (3)   
   Pfam (3)   
All databases (121)   

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