KEGG   Homo sapiens (human): 3837
Entry
3837              CDS       T01001                                 
Symbol
KPNB1, IMB1, IPO1, IPOB, Impnb, NTF97
Name
(RefSeq) karyopherin subunit beta 1
  KO
K14293  importin subunit beta-1
Organism
hsa  Homo sapiens (human)
Pathway
hsa03013  Nucleocytoplasmic transport
hsa05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 Nucleocytoplasmic transport
    3837 (KPNB1)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    3837 (KPNB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03009 Ribosome biogenesis [BR:hsa03009]
    3837 (KPNB1)
   03036 Chromosome and associated proteins [BR:hsa03036]
    3837 (KPNB1)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  Pre-40S particles
   Export and cytoplasmic maturation factors
    3837 (KPNB1)
  Pre-60S particles
    3837 (KPNB1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Spindle formation proteins
    3837 (KPNB1)
SSDB
Motif
Pfam: HEAT_EZ HEAT IBN_N HEAT_2 Arm Cnd1 Htt_N-HEAT_1 V-ATPase_H_C DUF6869
Other DBs
NCBI-GeneID: 3837
NCBI-ProteinID: NP_002256
OMIM: 602738
HGNC: 6400
Ensembl: ENSG00000108424
UniProt: Q14974
Structure
Position
17:47649919..47685505
AA seq 876 aa
MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQ
IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE
IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQG
MRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQN
LVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEA
AEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCE
DDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDP
SVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEA
AYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSA
KDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDA
LQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKN
YAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDI
ALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQ
ENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEAR
PMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA
NT seq 2631 nt   +upstreamnt  +downstreamnt
atggagctgatcaccattctcgagaagaccgtgtctcccgatcggctggagctggaagcg
gcgcagaagttcctggagcgtgcggccgtggagaacctgcccactttccttgtggaactg
tccagagtgctggcaaatccaggaaacagtcaggttgccagagttgcagctggtctacaa
atcaagaactctttgacatctaaagatccagatatcaaggcacaatatcagcagaggtgg
cttgctattgatgctaatgctcgacgagaagtcaagaactatgttttgcagacattgggt
acagaaacttaccggcctagttctgcctcacagtgtgtggctggtattgcttgtgcagag
atcccagtaaaccagtggccagaactcattcctcagctggtggccaatgtcacaaacccc
aacagcacagagcacatgaaggagtcgacattggaagccatcggttatatttgccaagat
atagacccagagcagctacaagataaatccaatgagattctgactgccataatccagggg
atgaggaaagaagagcctagtaataatgtgaagctagctgctacgaatgcactcctgaac
tcattggagttcaccaaagcaaactttgataaagagtctgaaaggcactttattatgcag
gtggtctgtgaagccacacagtgtccagatacgagggtacgagtggctgctttacagaat
ctggtgaagataatgtccttatattatcagtacatggagacatatatgggtcctgctctt
tttgcaatcacaatcgaagcaatgaaaagtgacattgatgaggtggctttacaagggata
gaattctggtccaatgtctgtgatgaggaaatggatttggccattgaagcttcagaggca
gcagaacaaggacggccccctgagcacaccagcaagttttatgcgaagggagcactacag
tatctggttccaatcctcacacagacactaactaaacaggacgaaaatgatgatgacgat
gactggaacccctgcaaagcagcaggggtgtgcctcatgcttctggccacctgctgtgaa
gatgacattgtcccacatgtcctccccttcattaaagaacacatcaagaacccagattgg
cggtaccgggatgcagcagtgatggcttttggttgtatcttggaaggaccagagcccagt
cagctcaaaccactagttatacaggctatgcccaccctaatagaattaatgaaagacccc
agtgtagttgttcgagatacagctgcatggactgtaggcagaatttgtgagctgcttcct
gaagctgccatcaatgatgtctacttggctcccctgctacagtgtctgattgagggtctc
agtgctgaacccagagtggcttcaaatgtgtgctgggctttctccagtctggctgaagct
gcttatgaagctgcagacgttgctgatgatcaggaagaaccagctacttactgcttatct
tcttcatttgaactcatagttcagaagctcctagagactacagacagacctgatggacac
cagaacaacctgaggagttctgcatatgaatctctgatggaaattgtgaaaaacagtgcc
aaggattgttatcctgctgtccagaaaacgactttggtcatcatggaacgactgcaacag
gttcttcagatggagtcacatatccagagcacatccgatagaatccagttcaatgacctt
cagtctttactctgtgcaactcttcagaatgttcttcggaaagtgcaacatcaagatgct
ttgcagatctctgatgtggttatggcctccctgttaaggatgttccaaagcacagctggg
tctgggggagtacaagaggatgccctgatggcagttagcacactggtggaagtgttgggt
ggtgaattcctcaagtacatggaggcctttaaacccttcctgggcattggattaaaaaat
tatgctgaataccaggtttgtttggcagctgtgggcttagtgggagacttgtgccgtgcc
ctgcaatccaacatcatacctttctgtgacgaggtgatgcagctgcttctggaaaatttg
gggaatgagaacgtccacaggtctgtgaagccgcagattctgtcagtgtttggtgatatt
gcccttgctattggaggagagtttaaaaaatacttagaggttgtattgaatactcttcag
caggcctcccaagcccaggtggacaagtcagactatgacatggtggattatctgaatgag
ctaagggaaagctgcttggaagcctatactggaatcgtccagggattaaagggggatcag
gagaacgtacacccggatgtgatgctggtacaacccagagtagaatttattctgtctttc
attgaccacattgctggagatgaggatcacacagatggagtagtagcttgtgctgctgga
ctaataggggacttatgtacagcatttgggaaggatgtactgaaattagtagaagctagg
ccaatgatccatgaattgttaactgaagggcggagatcgaagactaacaaagcaaaaacc
cttgctacatgggcaacaaaagaactgaggaaactgaagaaccaagcttga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (37)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (30)   
   RefSeq(nuc) (2)   
   GenBank (14)   
   EMBL (14)   
3D Structure (14)   
   PDB (14)   
Protein domain (9)   
   Pfam (9)   
All databases (101)   

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