KEGG   Homo sapiens (human): 3854
Entry
3854              CDS       T01001                                 
Symbol
KRT6B, CK-6B, CK6B, K6B, KRTL1, PC2, PC4
Name
(RefSeq) keratin 6B
  KO
K07605  type II keratin, basic
Organism
hsa  Homo sapiens (human)
Disease
H00684  Pachyonychia congenita
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    3854 (KRT6B)
   04147 Exosome [BR:hsa04147]
    3854 (KRT6B)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filaments
    Types I and II: Acidic and basic keratins
     3854 (KRT6B)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of epithelial cells
   3854 (KRT6B)
  Exosomal proteins of other body fluids (saliva and urine)
   3854 (KRT6B)
  Exosomal proteins of colorectal cancer cells
   3854 (KRT6B)
  Exosomal proteins of bladder cancer cells
   3854 (KRT6B)
SSDB
Motif
Pfam: Filament Keratin_2_head TPR_MLP1_2 CENP-F_leu_zip COG6_N ATG16 DUF745 Alanine_zipper Baculo_PEP_C RNase_PH ATG17_like DUF948 FapA APG6_N UPF0184 V_ATPase_I Virulence_fact DUF4407 ApoLp-III
Other DBs
NCBI-GeneID: 3854
NCBI-ProteinID: NP_005546
OMIM: 148042
HGNC: 6444
Ensembl: ENSG00000185479
UniProt: P04259
Position
12:complement(52446651..52452146)
AA seq 564 aa
MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRS
LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG
GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDK
VRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELR
NMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRA
LYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKY
EELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMAL
KDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEG
VGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRATGGGLS
SVGGGSSTIKYTTTSSSSRKSYKH
NT seq 1695 nt   +upstreamnt  +downstreamnt
atggccagcacatccaccaccatcaggagccacagcagcagccgccggggtttcagtgcc
aactcagccaggctccctggggtcagccgctctggcttcagcagcatctccgtgtcccgc
tccaggggcagtggtggcctgggtggcgcatgtggaggagctggctttggcagccgcagt
ctgtatggcctggggggctccaagaggatctccattggagggggcagctgtgccatcagt
ggcggctatggcagcagagccggaggcagctatggctttggtggcgccgggagtggattt
ggtttcggtggtggagccggcattggctttggtctgggtggtggagccggccttgctggt
ggctttgggggccctggcttccctgtgtgcccccctggaggcatccaagaggtcactgtc
aaccagagtctcctgactcccctcaacctgcaaattgaccccgccatccagcgggtgcgg
gccgaggagcgtgagcagatcaagaccctcaacaacaagtttgcctccttcatcgacaag
gtgcggttcctagagcagcagaacaaggttctggacaccaagtggaccctgctgcaggag
cagggcaccaagactgtgaggcagaacctggagccgttgttcgagcagtacatcaacaac
ctcaggaggcagctggacaacatcgtgggggaacggggtcgtctggactcggagctgaga
aacatgcaggacctggtggaggacctcaagaacaaatatgaggatgaaatcaacaagcgc
acagcagcagagaatgaatttgtgactctgaagaaggatgtggatgctgcctacatgaac
aaggttgaactgcaagccaaggcagacactcttacagatgagatcaacttcctgagagcc
ttgtatgatgcagagctgtcccagatgcagacccacatctcagacacatccgtggtgcta
tccatggacaacaaccgcaacctggacctggacagcatcatcgctgaggtcaaggcccaa
tatgaggagattgctcagaggagcagggctgaggctgagtcctggtaccagacaaagtac
gaggagctgcagatcacagcaggcagacatggggacgacctgcgcaacaccaagcaggag
attgctgagatcaaccgcatgatccagaggctgagatctgagatcgaccacgtcaagaag
cagtgtgccaacctacaggccgccattgctgatgctgagcagcgtggggagatggccctc
aaggatgctaagaacaagctggaagggctggaggatgccctgcagaaggccaagcaggac
ctggcccggctgctgaaggagtaccaggagctgatgaacgtcaagctggccctggatgtg
gagatcgccacctaccgcaagctgctggagggcgaggagtgcaggctgaatggcgaaggc
gttggacaagtcaacatctctgtagtgcagtccaccgtctccagtggctatggcggtgcc
agcggtgtcggcagtggcttaggcctgggtggaggaagcagctactcctatggcagtggt
cttggcgttggaggcggctttagttccagcagcggcagagccactgggggtggcctcagc
tctgttggaggcggcagttccaccatcaagtacaccaccacctcctcctccagcaggaag
agctacaagcactga

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Ontology (3)   
   KEGG BRITE (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
Protein domain (19)   
   Pfam (19)   
All databases (49)   

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